Uji Efektivitas Jeruk Nipis (Citrus aurantifolia) dalam Mempercepat Laju Disinfeksi Bakteri Escheria Coli pada Proses Solar Water Disinfection [PDF]
Solar Water Disinfection (SODIS) memerlukan waktu rata-rata berkisar antara 5-6 jam untuk dapat membunuh bakteri 3-4 Log pada air berkapasitas maksimal 2 liter atau 1 jam dengan suhu di atas 50°C.
Saprian Saprian +2 more
doaj +2 more sources
Cytochrome P450 CYP1B1 interacts with 8-methoxypsoralen (8-MOP) and influences psoralen-ultraviolet A (PUVA) sensitivity. [PDF]
BackgroundThere are unpredictable inter-individual differences in sensitivity to psoralen-UVA (PUVA) photochemotherapy, used to treat skin diseases including psoriasis. Psoralens are metabolised by cytochrome P450 enzymes (P450), and we hypothesised that
Yusuf Y Deeni +4 more
doaj +6 more sources
Phototoxic reaction due to solar radiation exposure in a psoriatic patient treated with PUVA therapy
A phototoxic reaction may be induced by additional exposure to solar radiation during photochemotherapy (psoralen, ultra-violet A – PUVA treatment). A woman was admitted to Dermatology and Venereology Clinic in Łódź as an emergency case due to extensive ...
Magdalena Salińska +4 more
doaj +1 more source
Synthesis and Biochemical Evaluation of Warhead-Decorated Psoralens as (Immuno)Proteasome Inhibitors
The immunoproteasome is a multicatalytic protease that is predominantly expressed in cells of hematopoietic origin. Its elevated expression has been associated with autoimmune diseases, various types of cancer, and inflammatory diseases.
Eva Shannon Schiffrer +7 more
doaj +1 more source
Psoralen and ultraviolet A light treatment directly affects phosphatidylinositol 3-kinase signal transduction by altering plasma membrane packing [PDF]
Psoralen and ultraviolet A light (PUNTA) are used to kill pathogens in blood products and as a treatment of aberrant cell proliferation in dermatitis, cutaneous T-cell lymphoma, and graft versus-host disease.
Compernolle, Veerle +7 more
core +2 more sources
Fotoferese extracorpórea Extracorporeal photopheresis
Fotoferese extracorpórea é uma modalidade de terapia celular que tem demonstrado eficácia e segurança em pacientes portadores de doenças auto-imunes e mediadas por células T, incluindo esclerodermia, linfoma de células T cutâneo/ Síndrome de Sézary e ...
Márcia M. Silva +1 more
doaj +1 more source
Synthesis of novel benzofurocoumarin analogues and their anti-proliferative effect on human cancer cell lines [PDF]
The synthesis of five new tetracyclic benzofurocoumarin (benzopsoralen) analogues is described. Their inhibitory effects on the growth of three human tumour cell lines (MDA MB 231 (breast adenocarcinoma), HeLa (cervix adenocarcinoma) and TCC-SUP (bladder
Campos, Ana M. F. Oliveira +4 more
core +1 more source
Isolation of furanocoumarins from Pastinaca sativa L. callus culture
Four furanocoumarins: bergapten, xanthotoxin, isopimpinellin (linear furanocoumarins) and sphondin (angular furanocoumarin) were isolated for the first time from callus tissues of Pastinaca sativa L.(Apiaceae) cultured in vitro on solid medium.
Halina Ekiert, Wanda Kisiel
doaj +1 more source
Transcutol® P Containing SLNs for Improving 8-Methoxypsoralen Skin Delivery
Topical psoralens plus ultraviolet A radiation (PUVA) therapy consists in the topical application of 8-methoxypsoralen (8-MOP) followed by the skin irradiation with ultraviolet A radiation.
Giulia Pitzanti +8 more
doaj +1 more source
Selective inhibition of carbonic anhydrase IX and XII by coumarin and psoralen derivatives
A small library of coumarin and their psoralen analogues EMAC10157a-b-d-g and EMAC10160a-b-d-g has been designed and synthesised to investigate the effect of structural modifications on their inhibition ability and selectivity profile towards carbonic ...
Rita Meleddu +12 more
doaj +1 more source

