TYMP upregulation mediated by the hyperactivated IL-17/NF-κB1 axis promotes psoriasis through enhancing aberrant keratinization and neutrophil-mediated inflammation. [PDF]
Wang J +7 more
europepmc +1 more source
New Biologic and Small Molecule Therapies for Hidradenitis Suppurativa
ABSTRACT Hidradenitis suppurativa (HS) is an inflammatory skin disease that has historically been underdiagnosed and, until recently, under‐researched. Furthermore, the pathophysiology of HS is complex, and not fully understood. Just three biologic medications—adalimumab (anti‐TNF‐α), secukinumab (anti‐IL17A) and bimekizumab (anti‐IL17A/F) are licensed
Emily Pender +2 more
wiley +1 more source
Increased Serum Cold-Inducible RNA-Binding Protein Levels in Psoriasis. [PDF]
Shin JM +6 more
europepmc +1 more source
JAK Inhibitors in Psoriatic–Atopic Dermatitis Overlap: A Four‑Case Series
ABSTRACT Overlap between psoriasis and atopic dermatitis (AD) poses diagnostic and therapeutic challenges; monoclonal antibodies targeting a single axis may improve one component while worsening the other [1]. Janus kinase (JAK) inhibitors act pleiotropically and may provide simultaneous control of psoriatic and eczematous inflammation [2].
Eleonora Bongiovanni +6 more
wiley +1 more source
Controlling Symptoms versus Minimizing Negative Treatment Impact: A Grounded Theory Study of Heterogeneity in Patient Preferences for Psoriasis Treatments. [PDF]
Szabo SM, Hawkins NS, Germeni E.
europepmc +1 more source
Approach to Nail Pitting in Pediatric and Adolescent Patients: A Dermatology Perspective
ABSTRACT This narrative review aims to discuss the etiologies of nail pitting in pediatric and adolescent patients, while providing a framework for further evaluation of possible underlying systemic conditions and their clinical findings from a dermatologic standpoint.
Elizabeth Botto +3 more
wiley +1 more source
Multi‑omics and their integration in psoriasis research (Review). [PDF]
Zhang H +6 more
europepmc +1 more source
Juvenile Generalized Pustular Psoriasis: Management in Children-A Case Series. [PDF]
Mishra P, Khadka A.
europepmc +1 more source
The Uncommon Coexistence of Mid-Borderline Leprosy and Generalized Pustular Psoriasis. [PDF]
Gunawan H +6 more
europepmc +1 more source

