Broadening the View: Substance P and Its Metabolism in Pruritus‐Related Diseases
ABSTRACT Chronic pruritus is a debilitating symptom accompanying numerous inflammatory skin diseases and remains a major therapeutic challenge. Neurogenic inflammation plays a central role in its pathogenesis, with the tachykinin substance P acting as a key mediator at the interface of the nervous system, immune cells, and cutaneous tissues.
Thomas Walter, Bjoern B. Burckhardt
wiley +1 more source
From Onset to Outcome: A Long-term Retrospective, Single centre Study of Guttate Psoriasis from Israel. [PDF]
Kassem R +8 more
europepmc +1 more source
ABSTRACT Background/Objectives Dupilumab is an anti‐interleukin (IL)‐4 receptor (IL‐4Rα) monoclonal antibody used to manage atopic dermatitis (AD). There is a paucity of real‐world Australian data for dupilumab in paediatric AD, especially regarding differences in clinical profiles between age groups.
Paul Sun Woo Kim +7 more
wiley +1 more source
Economic Impact of Timely Systemic Treatment of Psoriatic Disease in Comorbidity Risk Reduction: Literature Review and (Early) Economic Assessment. [PDF]
Norton N +5 more
europepmc +1 more source
ABSTRACT Background Skin disease is a major cause of morbidity in Australia and a leading reason for primary care visits. Aboriginal and Torres Strait Islander peoples experience a disproportionate burden of skin conditions but face barriers to accessing culturally safe specialist services.
Nikhil Dwivedi +6 more
wiley +1 more source
Intravital Monitoring of Psoriasis Treatment Response and Drug Delivery Using Multiphoton Fluorescence Lifetime Imaging. [PDF]
Nguyen L +4 more
europepmc +1 more source
Effect of Anti‐IL‐23 and Anti‐IL‐17 Therapy on Darier Disease: A Case Series
ABSTRACT Darier disease is a rare ATP2A2‐related genodermatosis for which therapeutic options remain limited, as acitretin is often constrained by toxicity and teratogenicity. In this retrospective real‐world case series of eight patients, anti‐IL‐17 therapy showed a more consistent early signal of clinical benefit than anti‐IL‐23 therapy, with greater
Maione Vincenzo +6 more
wiley +1 more source
ABSTRACT Background/Objectives Vitiligo is associated with substantial psychosocial burden; however, community‐based patient‐reported data remain limited, and existing instruments may not fully reflect patients' lived experience. This study explored the psychosocial impacts of vitiligo using social media‐based recruitment.
Megan Noda +2 more
wiley +1 more source
Efficacy of Bimekizumab on Palmoplantar Psoriasis: A 16-Week Multicenter Retrospective Study-IL PSO (Italian Landscape PSOriasis). [PDF]
Burlando M +24 more
europepmc +1 more source
Psoriasis in skin of color: clinical presentation, diagnostic challenges, and therapeutic considerations. [PDF]
Costa A, Romiti R.
europepmc +1 more source

