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Psoriatic arthritis [PDF]

Nature Reviews Disease Primers, 2019
Psoriatic arthritis (PsA) is a complex inflammatory disease with heterogeneous clinical features, which complicates psoriasis in 30% of patients. There are no diagnostic criteria or tests available. Diagnosis is most commonly made by identifying inflammatory musculoskeletal features in joints, entheses or the spine in the presence of skin and/or nail ...
O. FitzGerald, A. Ogdie, V. Chandran, L. Coates, A. Kavanaugh, W. Tillett, Ying-Ying Leung, M. deWit, J. Scher, P. Mease   +9 more
semanticscholar   +8 more sources

Psoriatic arthritis [PDF]

Expert Opinion on Investigational Drugs, 2000
Psoriatic arthritis occurs in 5 - 42% of patients with psoriasis. It is an inflammatory arthritis distinct from rheumatoid, being usually sero-negative, asymmetrical and often affecting the spine, sacro-iliac and distal interphalangeal joints. It runs a very variable course, from a mild non-destructive disease to a severe rapidly progressive erosive ...
Costantino Pitzalis, Nicolò Pipitone
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Correction to "Impact of Delay of Treatment With Disease-Modifying Antirheumatic Drugs in Psoriatic Arthritis: The CorEvitas Psoriatic Arthritis/Spondyloarthritis Registry". [PDF]

ACR Open Rheumatol
ACR Open Rheumatology, Volume 7, Issue 8, August 2025.
europepmc   +2 more sources

Psoriatic Arthritis [PDF]

Global Advances in Health and Medicine, 2012
Autoimmune diseases (ADs) are chronic, often debilitating and potentially life-threatening conditions that collectively affect up to 23.5 million Americans, and their incidence is rising.1 They are heterogeneous in pathology but share common etiopathogenic factors such as intestinal hyperpermeability.2 Although up to 100 ADs have been identified ...
Kara Fitzgerald, Mark Hyman, Mark Hyman, Kathie Swift   +3 more
  +7 more sources

Psoriatic arthritis [PDF]

Polish Journal of Radiology, 2013
Psoriatic arthritis (PsA) is a chronic inflammatory joint disease which develops in patients with psoriasis. It is characteristic that the rheumatoid factor in serum is absent. Etiology of the disease is still unclear but a number of genetic associations have been identified.
Sankowski, Artur Jacek, Łebkowska, Urszula Maria, Ćwikła, Jarosław, Walecka, Irena, Walecki, Jerzy   +4 more
  +6 more sources

Psoriatic Arthritis: Pathogenesis and Targeted Therapies

International Journal of Molecular Sciences, 2023
Psoriatic arthritis (PsA), a heterogeneous chronic inflammatory immune-mediated disease characterized by musculoskeletal inflammation (arthritis, enthesitis, spondylitis, and dactylitis), generally occurs in patients with psoriasis.
A. B. Azuaga, J. Ramírez, J. Cañete
semanticscholar   +1 more source

Efficacy and Safety of the TYK2/JAK1 Inhibitor Brepocitinib for Active Psoriatic Arthritis: A Phase IIb Randomized Controlled Trial

Arthritis & Rheumatology, 2023
Brepocitinib is a TYK2/JAK1 inhibitor in development for the treatment of several immunologic diseases. The efficacy and safety of oral brepocitinib were assessed in participants with moderately‐to‐severely active psoriatic arthritis (PsA) for up to 52 ...
P. Mease, P. Helliwell, Paula Silwinska-Stanczyk, M. Miakisz, A. Ostor, E. Peeva, M. Vincent, Qiankun Sun, V. Sikirica, R. Winnette, R. Qiu, Gang Li, G. Feng, J. Beebe, D. Martin   +14 more
semanticscholar   +1 more source

Group for Research and Assessment of Psoriasis and Psoriatic Arthritis (GRAPPA): updated treatment recommendations for psoriatic arthritis 2021

Nature Reviews Rheumatology, 2022
Since the second version of the Group for Research and Assessment of Psoriasis and Psoriatic Arthritis (GRAPPA) treatment recommendations were published in 2015, therapeutic options for psoriatic arthritis (PsA) have advanced considerably.
L. Coates, E. Soriano, N. Corp, H. Bertheussen, K. Callis Duffin, Cristiano B. Campanholo, J. Chau, L. Eder, D. Fernández-Ávila, Oliver FitzGerald, A. Garg, D. Gladman, N. Goel, Philip S Helliwell, M. Husni, D. Jadon, Arnon Katz, Dhruvkumar Laheru, J. Latella, Ying-Ying Leung, C. Lindsay, E. Lubrano, L. Mazzuoccolo, P. Mease, D. O'Sullivan, A. Ogdie, W. Olsder, P. Palominos, L. Schick, I. Steinkoenig, M. D. de Wit, D. A. van der Windt, A. Kavanaugh, Cristiano Oliver Dafna Philip M. Elaine Dhrukumar Ying-Ying Campanholo Fitzgerald Gladman Helliwell Husni Lahe, Cristiano B. Campanholo, Oliver FitzGerald, D. Gladman, Philip S Helliwell, Dhrukumar Laheru, Ying-Ying Leung, E. Lubrano, L. Mazzuoccolo, P. Mease   +42 more
semanticscholar   +1 more source

Association Between Inflammatory Bowel Disease and Both Psoriasis and Psoriatic Arthritis: A Bidirectional 2-Sample Mendelian Randomization Study.

JAMA dermatology, 2022
Importance Psoriasis, psoriatic arthritis, and inflammatory bowel disease, ie, Crohn disease and ulcerative colitis, are chronic systemic immune-mediated disorders affecting an increasing proportion of adults and children worldwide. Observational studies
D. Freuer, J. Linseisen, C. Meisinger
semanticscholar   +1 more source

Long-term Safety of Secukinumab Over Five Years in Patients with Moderate-to-severe Plaque Psoriasis, Psoriatic Arthritis and Ankylosing Spondylitis: Update on Integrated Pooled Clinical Trial and Post-marketing Surveillance Data

Acta Dermato-Venereologica, 2022
Secukinumab, a selective interleukin (IL)-17A inhibitor, is approved for use in adult and paediatric psoriasis, psoriatic arthritis, ankylosing spondylitis and non-radiographic axial spondyloarthritis.
A. Gottlieb, A. Deodhar, I. McInnes, X. Baraliakos, K. Reich, S. Schreiber, W. Bao, K. Marfo, H. Richards, L. Pricop, A. Shete, V. Trivedi, Deborah Keefe, C. Papavassilis, P. Jagiello, P. Papanastasiou, P. Mease, M. Lebwohl   +17 more
semanticscholar   +1 more source