Results 191 to 200 of about 27,084 (310)

Academic Motivation, Fear of Negative Evaluation, Self-Efficacy, and Self-Regulated Learning: Role of Affective Mechanisms in the Learning Process. [PDF]

BMC Psychol
Toprak E, Yavuz E.
europepmc   +1 more source

Mechanism and Intervention of the NPY1R/CREB Signaling Axis in Regulating Inflammatory Response in Aged Ovarian Granulosa Cells and Ovarian Senescence

The FASEB Journal, Volume 40, Issue 12, 30 June 2026.
Aging‐associated upregulation of NPY1R drives p‐CREB activation, triggering inflammation, mitochondrial dysfunction, and extracellular matrix imbalance to promote ovarian senescence. Pharmacological inhibition of NPY1R with BIBO 3304 restores ovarian homeostasis, highlighting a therapeutic strategy for reproductive aging. ABSTRACT Ovarian senescence is
Junnan Fang, Chaoying Wang, Shuaishuai Guo, Yiping Zhang, Yang Zhang, Huihui Wang, Yue Kong, Haixia Jin, Lin Qi, Yan Liu, Zhaoting Wu, Fuli Zhang, Shuang Wen, Xiaopeng Wang, Guang Yang, Guidong Yao   +15 more
wiley   +1 more source

Factors influencing anime-generated parasocial relationships: a systematic review. [PDF]

BMC Psychol
Archana V, Arora A, Saha PKR, Pandey V, Jyothiswarup G.   +4 more
europepmc   +1 more source

A Nano‐Interception Strategy for Chronic Heart Failure: Prussian Blue Nanoparticles Disrupt Fibroblast‐Immune Communication via CCL2 Sequestration

Advanced Materials, Volume 38, Issue 31, 2 June 2026.
A nano‐interception strategy disrupts pathogenic fibroblast–macrophage crosstalk in chronic heart failure. Scalable Prussian blue nanoparticles selectively sequester CCL2 via ultrahigh‐affinity binding, preventing CCR2+ macrophage recruitment and breaking a key fibro‐inflammatory circuit. This approach demonstrates robust efficacy in murine and porcine
Bo Chen, Gao Wei, Guowei Zeng, Haoyu Li, Rongrong Wu, Hongyu Yan, Zijie Zhou, Kai Luo, Xiaoyang Zhang, Cong Li, Longming Huang, Lingyan Cheng, Xinjie Zhang, Jinghao Zheng, Bozhong Shi, Xiaojun Cai, Xiaomin He   +16 more
wiley   +1 more source

Partial sensory rhizotomy in therapy-refractory and recurrent trigeminal neuralgia - a single center experience. [PDF]

Acta Neurochir (Wien)
Lange I, El Refaee E, Matthes M, Schroeder HWS, Baldauf J.   +4 more
europepmc   +1 more source

T Cell Exhaustion in Cancer Immunotherapy: Heterogeneity, Mechanisms, and Therapeutic Opportunities

Advanced Science, Volume 13, Issue 35, 24 June 2026.
T cell exhaustion limits immunotherapy efficacy. This article delineates its progression from stem‐like to terminally exhausted states, governed by persistent antigen, transcription factors, epigenetics, and metabolism. It maps the exhaustion landscape in the TME and proposes integrated reversal strategies, providing a translational roadmap to overcome
Yang Yu, Xiaoyu Yao, Qingyang Wang, Mengrui Yang, Runze Li, Jiangjiang Qin, Jing Zhuang, Changgang Sun   +7 more
wiley   +1 more source

Upstream migration capacity of Acrossocheilus fasciatus: Behavioral strategies in response to hydraulic conditions and implications for low-head weir design. [PDF]

PLoS One
Wang B, Xu G, Fu L, You A, Xu Z, Ling Y.
europepmc   +1 more source

Self‐Heating and Thermal Gradient in Solid‐State Batteries: Friend or Foe?

Advanced Energy Materials, Volume 16, Issue 24, 24 June 2026.
This work investigates the role of self‐heating and thermal gradients derived from the kinetics/transport interactions within the cathode microstructure, electrode architecture, and operating regimes, thus encouraging a mechanism‐centric design of anode‐free solid‐state batteries for next‐generation high‐power applications.
Abhinand Ayyaswamy, Bairav S. Vishnugopi, Partha P. Mukherjee   +2 more
wiley   +1 more source

Double‐Stranded DNA Sensing cGAS‐STING Immune Signaling in a Rat Co‐Culture Model of the Blood–Brain Barrier

Cell Biochemistry and Function, Volume 44, Issue 6, June 2026.
ABSTRACT Double‐stranded DNA coming from, for example, viruses, bacteria, or apoptotic cells is recognized by the cGAS‐STING signaling pathway comprising the cyclic GMP‐AMP synthase (cGAS) and the stimulator of interferon genes (STING) receptors. The pathway induces type I interferon response and activates transcription of interferon‐stimulated genes ...
András Harazin, Line S. Reinert, Parvez Alam, Lea Hoy, Annemette Boe Marnow, Janni Nielsen, Anna Lorentzen, Daniel E. Otzen, Søren R. Paludan, Morten S. Nielsen   +9 more
wiley   +1 more source

Ovarian Fibrosis Through Comparative Analysis of Collagen Architecture. [PDF]

Mol Reprod Dev
Aitken CJ, Kadhim L, Murray A, Landry DA.   +3 more
europepmc   +1 more source