Results 81 to 90 of about 38,559 (244)

Breaking Out of One’s Head (& Awakening to the World) [PDF]

, 2019
Herein, I review the shattering moment in my life when I awoke from the dream of self to find being as part of the living world and not in my head, discovering my perspectival center to be literally everywhere.
Nixon, Gregory
core  

25C-NBOMe: preliminary data on pharmacology, psychoactive effects, and toxicity of a new potent and dangerous hallucinogenic drug [PDF]

, 2014
Introduction. The use of novel psychoactive substances (NPSs) has rapidly increased as well as their online availability. The aim of this paper is to provide a comprehensive review of the nature and the risks associated with 25C-NBOMe, which has recently
BERSANI, FRANCESCO SAVERIO, BERSANI, Giuseppe, Eduardo Cinosi, Fabrizio Schifano, Flaminia Bolzan Mariotti Posocco, Gabriella Albano, Giovanni Martinotti, Giuseppe Valeriani, Ornella Corazza, Pierluigi Simonato, Rita Santacroce   +10 more
core   +5 more sources

The Australia story: Current status and future challenges for the clinical applications of psychedelics

British Journal of Pharmacology, EarlyView.
Abstract The past decade has seen a huge increase in clinical research with psychedelic drugs and 3,4‐methylenedioxymethamphetamine (MDMA), which have revealed great potential for treating mental health conditions. Given this progress in research, as well as the current unmet clinical need of millions of patients, in 2023, the Australian Therapeutic ...
David J Nutt, Peter Hunt, Anne Katrin Schlag, Paul Fitzgerald   +3 more
wiley   +1 more source

Effects of DMT on mental health outcomes in healthy volunteers

Scientific Reports
Psilocybin, a serotonergic psychedelic, is being increasingly researched in clinical studies for the treatment of psychiatric disorders. The relatively lengthy duration of oral psilocybin’s acute effects (4–6 h) may have pragmatic and cost-effectiveness ...
Christopher Timmermann, Richard J. Zeifman, David Erritzoe, David J. Nutt, Robin L. Carhart-Harris   +4 more
doaj   +1 more source

Insights into the pathogenesis of nicotine addiction. Could a salivary biosensor be useful in Nicotine Replacement Therapy (NRT)? [PDF]

, 2019
Nicotine has gained the attention of the medical community due to its insidious addictive mechanisms which lead to chronic consumption. The multitude of compounds derived from tobacco smoke have local and systemic negative impacts, resulting in a large ...
Alexescu, Teodora G, Bordea, Roxana, Boșca, Bianca A, Băbțan, Anida-Maria, Câmpian, Radu S, Feurdean, Claudia N, Ilea, Aranka, Ionel, Anca, Miclăuș, Viorel, Mirică, Codruța I, Petrescu, Nausica B, Ruxanda, Flavia, Todea, Adina D, Uriciuc, Willi A   +13 more
core   +2 more sources

Holistic approach to substance‐induced psychosis

Addiction, EarlyView.
Julia M. Lappin, Shane Darke, Michael Farrell   +2 more
wiley   +1 more source

Psilocybin as a novel treatment for chronic pain

British Journal of Pharmacology, EarlyView.
Abstract Psychedelic drugs are under active consideration for clinical use and have generated significant interest for their potential as anti‐nociceptive treatments for chronic pain, and for addressing conditions like depression, frequently co‐morbid with pain.
Tate Askey, Reena Lasrado, Maria Maiarú, Gary J. Stephens   +3 more
wiley   +1 more source

DOES THE PHENOMENOLOGY OF THE PSILOCYBIN EXPERIENCE PREDICT LONG-TERM EFFECTS ON MOOD AND WELL-BEING IN HEALTHY VOLUNTEERS?

IBRO Neuroscience Reports, 2023
Tomáš Páleníček, Tereza Kluckova, Marek Nikolic, Cestmir Vejmola, Filip Tyls, Vojtech Viktorin, Jiří Horáček, Martin Brunovsky   +7 more
doaj   +1 more source

An investigation of acute physiological and psychological moderators of psychedelic-induced personality change among healthy volunteers

Neuroscience Applied
This study investigated the effects of a single high-dose of psilocybin on personality traits in psychedelic-naïve healthy volunteers. These data originate from a larger within-subjects fixed-order design trial, where a single high dose of psilocybin (25 
Kate Godfrey, Brandon Weiss, Xinhu Zhang, Meg Spriggs, Joseph Peill, Taylor Lyons, Robin Carhart-Harris, David Erritzoe   +7 more
doaj   +1 more source

Neuropsychopharmacology of hallucinogenic and non‐hallucinogenic 5‐HT2A receptor agonists

British Journal of Pharmacology, EarlyView.
Psychedelic drugs such as LSD and psilocin were once relegated to the fringes of medical research because of their association with counterculture movements and a perceived concern about harm through recreational use, and their consequent legal prohibition in the early 1970s.
Trevor Sharp, Aurelija Ippolito
wiley   +1 more source