Systemic Corticosteroids in the Management of Sinonasal Disease: An Evidence‐Based Expert Review
ABSTRACT Background Chronic rhinosinusitis (CRS) is a prevalent, heterogeneous inflammatory disease associated with significant morbidity. Systemic corticosteroids (SCS) are commonly prescribed for their anti‐inflammatory effects, but cumulative exposure carries risks, including metabolic, cardiovascular, and skeletal complications.
Andrew Thamboo +28 more
wiley +1 more source
A Ten-Year Cohort Study on the Stability and Trajectories of Psychiatric Diagnosis in Adolescents and Young Adults in Lazio, Italy. [PDF]
Forastiere A +4 more
europepmc +1 more source
Increasing the Role of Phenomenology in Psychiatric Diagnosis-The Clinical Staging Approach. [PDF]
Drożdżowicz A.
europepmc +1 more source
The graphical abstract shows how molecular biology research has shifted from using traditional animal models toward using methods that are more relevant to humans. It points out the main problems, differences between species, difficulty in reproducing results, moral issues, and lack of infrastructure that make translational accuracy harder to achieve ...
Md. Shajid Hossain Rafi +6 more
wiley +1 more source
Multimorbidity and Associations with Cognition and Alzheimer's Disease Biomarkers
Objective Multimorbidity, the coexistence of 2 or more chronic conditions, has been linked to cognitive aging and Alzheimer's disease (AD) and AD‐related dementias, yet the mechanisms remain unclear. We aimed to examine the associations of multimorbidity with cognition and biomarkers across multiple mechanistic pathways.
Xiaqing Jiang +45 more
wiley +1 more source
Racial bias in AI-mediated psychiatric diagnosis and treatment: a qualitative comparison of four large language models. [PDF]
Bouguettaya A, Stuart EM, Aboujaoude E.
europepmc +1 more source
Objective Accurately predicting future hemorrhagic events in patients with cerebral amyloid angiopathy (CAA) remains a major clinical challenge. It is unknown whether cerebrospinal fluid (CSF) biomarkers of amyloid‐beta (Aβ) pathology are associated with increased hemorrhage risk in this population.
Philipp Arndt +15 more
wiley +1 more source
Analysis of Consistency Between Forensic Psychiatric Evaluation Diagnosis and Previous Clinical Psychiatric Diagnosis: A Retrospective Study. [PDF]
Li M +11 more
europepmc +1 more source
Objective Parkinson's disease (PD) is increasingly conceptualized as a disorder of large‐scale brain networks, yet whether and how frequency‐specific functional connectivity reorganizes across stages remains poorly understood. In this study, we used high‐density electroencephalography (EEG) to characterize cortico‐cortical functional connectivity ...
Matteo Conti +15 more
wiley +1 more source
Editorial: AI approach to the psychiatric diagnosis and prediction. [PDF]
Gao W, Lu L, Yin X.
europepmc +1 more source

