Results 81 to 90 of about 2,806,130 (244)

Generation of a human induced pluripotent stem cells line (JNMUi001-A) from peripheral blood mononuclear cells of a male patient with schizophrenia

Stem Cell Research
We collected a blood sample from a 35-year-old male diagnosed with schizophrenia, isolated peripheral blood mononuclear cells, and generated a human induced pluripotent stem cells (hiPSCs) line using non-integrative reprogramming techniques.
Yuxing Long, Meixiang Jiang, Yiliang Liu, Ran Li, Jingyi Xu, Tongyue Chi, Menglu Sun, Miao Li, Hao Yu, Xiaobo Han   +9 more
doaj   +1 more source

Boundary‐Dependent Sleep–Wake Dysregulation in Idiopathic Hypersomnia

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Idiopathic hypersomnia (IH) presents with excessive daytime sleepiness (EDS) despite apparently preserved nocturnal sleep, challenging traditional models of hypersomnolence based on sleep loss or fragmentation. We aimed to test the hypothesis that EDS in IH reflects excessive stabilization of the sleep state, consistent with ...
Samantha Mombelli, Karine Lacourse, Hélène Blais, Anne‐Sophie Deshaies‐Rugama, Cynthia Thompson, Alex Desautels, Jacques Montplaisir, Milan Nigam, Christophe Moderie, Boshra Khajehpiri, Catherine Duclos, Jean Marc Lina, Julie Carrier, Nadia Gosselin   +13 more
wiley   +1 more source

Establishment of an induced pluripotent stem cell (iPSC) line (JNMUi002-A) from a male patient with schizophrenia

Stem Cell Research
We obtained Peripheral blood mononuclear cells (PBMCs) from a peripheral blood sample of a 19-year-old male schizophrenia patient and successfully established induced pluripotent stem cell (iPSC) line using non-integrated reprogramming technology.
Meixiang Jiang, Yuxing Long, Yiliang Liu, Ran Li, Jingyi Xu, Tongyue Chi, Menglu Sun, Miao Li, Hao Yu, Lu Yu, Xiaobo Han   +10 more
doaj   +1 more source

Association between childhood abuse and psychiatric morbidities among hospitalized patients

Indian Journal of Social Psychiatry, 2016
Background: Childhood abuse has been linked with increased risk of adult psychiatric disorders including major depression, substance abuse, anxiety disorders, posttraumatic stress disorder, and personality disorders.
Kshirod Kumar Mishra, Ramdas Ransing, Praveen Khairkar, Sakekar Gajanan   +3 more
doaj   +1 more source

Utility of the APE2 Score as a Diagnostic Tool for Autoimmune Encephalitis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To retrospectively evaluate the diagnostic performance of the Antibody Prevalence in Epilepsy and Encephalopathy (APE2) score relative to clinician‐adjudicated autoimmune encephalitis (AE) and the Graus criteria in a tertiary neuroimmunology referral cohort, including antibody‐negative AE.
Bijoya Basu, Sophia F. Damman, Samhitha M. Rai, Hesham Abboud   +3 more
wiley   +1 more source

Diagnosis of psychiatric and nervous system disease by province and year.

, 2022
Diagnosis of psychiatric and nervous system disease by province and year.
Xueqing Wang (210284), Andrew Francis-Tan (14149717)   +1 more
core   +1 more source

Subjective Cognitive Concerns and Cognitive Trajectories in Parkinson's Disease: Biomarker Impact

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To examine the relationship of subjective cognitive concerns (SCC) with biomarkers of Alzheimer's disease (AD), neurodegeneration, and Parkinson's disease (PD) and domain‐specific cognitive trajectories among cognitively unimpaired persons with de novo PD. Method Cognitively unimpaired participants with SCC (n = 294) and without SCC (
Francesca V. Lopez, Fareshte Erani, Katherine J. Bangen, David G. Coughlin, Douglas Galasko, Kelsey R. Thomas   +5 more
wiley   +1 more source

Minimally Verbal Individuals with Autism Spectrum Disorders/Intellectual Disability and Challenging Behaviors: Can Strategic Psychiatric Treatment Help?

Disabilities
(1) Background: Psychiatrists are increasingly required to treat minimally verbal (MV) individuals with autism spectrum disorder (ASD), intellectual disability (ID) and behavior problems without much published guidance. (2) Methods: We reviewed 80 charts
Jessica A. Hellings, Saras Chen Singh, Sham Singh, An-Lin Cheng   +3 more
doaj   +1 more source

Psychiatric diagnosis: impersonal, imperfect and important

, 2014
Psychiatric diagnosis is in the spotlight following the recent publication of DSM-5. In this article we consider both the benefits and limitations of diagnosis in psychiatry.
Craddock, Nicholas John, Mynors-Wallis, L.   +1 more
core   +1 more source

Cerebrospinal Fluid Over Plasma Links Analytes to Cognitive Decline in Older Adults at Risk for Alzheimer's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To identify inflammatory analytes in cerebrospinal fluid (CSF) and plasma associated with cognitive decline in cognitively normal (CN) older adults at risk for Alzheimer's disease (AD). Methods In a longitudinal study of 118 CN older adults (65–80 years, 54% APOE ε4, 26% preclinical AD), 1331 CSF and 1501 plasma analytes were ...
Jagan A. Pillai, Audrey Zhu, Chunxuan Ma, Ming Wang, Yifan Yang, Lynn M. Bekris, Maria Khrestian, Frank P. DiFilippo, Mikhail Nasrallah, Aaron Burberry, James B. Leverenz, Yuan Hou, Feixiong Cheng, Stephen M. Rao   +13 more
wiley   +1 more source