Results 121 to 130 of about 4,936,765 (261)

Validity and test–retest reliability of the Swedish version of the Geriatric Depression Scale among very old adults

BMC Geriatrics
Background The Geriatric Depression Scale (GDS) has shown good validity and reliability, but few studies have examined the GDS among very old adults or the Swedish translation.
Sandra Snellman, Carl Hörnsten, Birgitta Olofsson, Yngve Gustafson, Hugo Lövheim, Johan Niklasson   +5 more
doaj   +1 more source

Health needs assessment: development of a simplified risk probability scale design for rapid mental health screening in emergency frontline rescue teams

Frontiers in Public Health
BackgroundEmergency frontline rescue workers during the COVID-19 pandemic faced elevated psychological risks, yet existing tools lack specificity for crisis contexts.AimTo develop a simplified risk probability scale (SRPS) tailored for rapid self ...
Yifei Chen, Yan Bo, Zhuanzhuan Han, Guowei Fan   +3 more
doaj   +1 more source

Remote Magnetomechanical Neuromodulation Uncovers Therapeutic Mechanisms for Alleviating Parkinsonian Symptoms in Freely Moving Mice

Advanced Science, EarlyView.
Magnetomechanical neuromodulation using magnetic nanodiscs enables remote activation of neurons. In a hemiparkinsonian mouse model, alternating magnetic fields actuate the nanodiscs to generate torque that opens mechanosensitive ion channels within the subthalamic nucleus, thereby modulating basal ganglia motor circuitry.
Anouk Wolters, Lorenzo Signorelli, Christian Herff, Sophia Gimple, Renzo Riemens, Gunter Kenis, Kim Rijkers, Hamed Shabani, Jyh‐Jang Sun, Yasin Temel, Hans Clusmann, Danijela Gregurec, Sarah‐Anna Hescham   +12 more
wiley   +1 more source

The assessment of anxiety levels in patients with posttraumatic stress disorder

Acta Orthopaedica et Traumatologica Turcica, 2020
Objectives: The purpose of this study was to measure state and trait anxiety levels of veterans who developed posttraumatic stress disorder following combat or landmine injuries, or vehicle accidents.\nMethods: The anxiety levels of 98 veterans (mean age
Ebru Sinici, Cemil Yildiz, Servet Tunay, Huseyin Ozkan, Mehmet Altinmakas   +4 more
doaj  

Association of the more favourable counsellor-assessed outcomes with larger improvements in the client rating scales.

, 2016
Box-plot shows the distribution of change in rating scales (complaint, functioning) for each status (increased, same, improved, resolved) at client’s last visit as assessed by the counsellor (n = 6,988).
Trudy Mooren (2836913), Giovanni Pintaldi (2836919), Cono Ariti (552950), Leslie Shanks (140067), Kaz de Jong (59434), Rolf Kleber (2836916), Saskia van der Kam (168566)   +6 more
core   +1 more source

Gestational Hypoxia Disrupts Medial Ganglionic Eminence Progenitor Dynamics and Interneuron Development in Schizophrenia

Advanced Science, EarlyView.
FES‐derived MGE spheroids exhibit progenitor‐stage alterations in developmental trajectory and hypoxia‐responsive transcriptional programs, followed by functional disruption. Gestational hypoxia recapitulates impaired progenitor proliferation, shortened cell‐cycle progression, interneuron developmental abnormalities, and schizophrenia‐like behaviors in
Peiyan Ni, Qiancheng Zhang, Youhui Jiang, Huiying Yao, Chuqing Zhou, Xiaoyi Tian, Shiyingnan Gao, Jun Zhao, Xinyi Ren, Naxin Xu, Mengshan Fu, Liansheng Zhao, Xueyu Qi, Xueli Yu, Wanjun Guo, Sangmi Chung, Fan Guo, Tao Li   +17 more
wiley   +1 more source

Depression, anxiety, stress and adverse childhood experience among first-year university students

Journal of Family Medicine and Primary Care
Objective: The purpose of this research was to examine the levels of Depression, Anxiety, Stress (DAS) and adverse childhood experiences (ACEs) in first-year university students in Saudi Arabia.
Samah Khalid Alharthi, Sulhi Ali Alfakeh, Jumana Turki Aljohani   +2 more
doaj   +1 more source

14‐3‐3γ Protects Against Postoperative Cognitive Dysfunction by Regulating Tau Thr205 Phosphorylation and Synaptic Integrity

Advanced Science, EarlyView.
Integrative multi‐cohort analyses identify 14‐3‐3γ as a biomarker and regulator of cognitive vulnerability. Experimental studies show that 14‐3‐3γ loss is associated with Tau Thr205 phosphorylation, synaptic dysfunction, and cognitive impairment, while genetic overexpression or pharmacological stabilization of 14‐3‐3γ confers protective effects in ...
Shouqiang Zhu, Xue Han, Heng Zhang, Chang Ye, Tianjiao Xia, Xiaoping Gu   +5 more
wiley   +1 more source

Genome-wide association study of behavioural and psychiatric features in human prion disease. [PDF]

, 2015
Prion diseases are rare neurodegenerative conditions causing highly variable clinical syndromes, which often include prominent neuropsychiatric symptoms.
Carswell, C, MacKay, A, Thompson, AG, Porter, MC, Rudge, P, Collinge, J, Lowe, J, Mead, S, Uphill, J, Lukic, A   +9 more
core  

Incremental Validity of the MMPI-2 Content Scales in a Psychiatric Sample

, 1996
The current study replicated and expanded previous investigations that focused on the incremental contribution of the Minnesota Multiphasic Personality Inventory-2 (MMPI-2) content scales.
Robert Aiduk, Richard Griffin, Robert P. Archer, David E. Elkins   +3 more
core   +1 more source