Results 101 to 110 of about 45,851 (297)

Depression, cortisol, and suppressed cell-mediated immunity in metastatic breast cancer

, 2009
Cancer treatment is known to have significant immuno-suppressive/dysregulatory effects. Psychological distress and depression, which often accompany cancer diagnosis and treatment, can also suppress or dysregulate endocrine and immune function.
Keuroghlian, Alex S, Bruce S. McEwen, Sephton, Sandra E, McEwen, Bruce S, Sandra E. Sephton, Spiegel, David, Firdaus S. Dhabhar, David Spiegel, Alex S. Keuroghlian, Janine Giese-Davis, Dhabhar, Firdaus S, Giese-Davis, Janine, Alexei C. Ionan, Ionan, Alexei C   +13 more
core   +1 more source

Exploring Resilience When Living with a Wound — An Integrative Literature Review [PDF]

, 2014
The psychological impact for patients with wounds can be significant, and adverse psychological effects frequently occur when there are permanent changes in the body’s structure or function.
Karen-leigh Edward, Edward, Karen-Leigh, Karen Ousey, Ousey, Karen   +3 more
core   +1 more source

Evaluation of quantitative muscle MRI and an intelligent phenotyping housing system as advanced phenotyping methods in a mouse model of calpain 3‐deficient muscular dystrophy

Animal Models and Experimental Medicine, EarlyView.
We applied quantitative MRI of the lower limb and automated home‐cage phenotyping to a mouse model of calpainopathy to detect early disease changes. At 15 months, calpain 3‐deficient mice showed increased water T2 values correlating with immune cell infiltration in the soleus and gastrocnemius muscles, while assessment of motor activity revealed only ...
Nicolina Südkamp, Marlena Rohm, Gabriele Russo, Xavier Helluy, Abdulhadi Kocabas, Martijn Froeling, Felix Kleefeld, Denise Manahan‐Vaughan, Tobias Ruck, Frank Jacobsen, Matthias Vorgerd, Johannes Forsting, Lara Schlaffke   +12 more
wiley   +1 more source

Citrus aurantium honey‐mediated gut homeostasis and anti‐inflammation via Thorl/Nprl2‐TORC1 signaling: Network pharmacology and Drosophila validation

Animal Models and Experimental Medicine, EarlyView.
The study employed a four‐tiered strategy: (1) UHPLC‐FTMS profiling of Citrus aurantium honey to characterize its chemical composition; (2) network pharmacology analysis integrating target prediction, protein–protein interaction networks, and KEGG pathway enrichment to identify the Thor1/Nprl2‐TORC1 axis as a key mechanistic pathway; (3) in vitro ...
Wenqi Wan, Ruiguang Huang, Shuqiong Cao, Luxia Pan, Wenkai Zhang, Wujun Jiang, Zhiyong Liu   +6 more
wiley   +1 more source

A Cross-Cultural Scrutiny of Predictors of English Teachers’ Immunity in the Contexts of Iran, France, and the United States

SAGE Open
Recent research on language teacher factors has focused on the construct of teacher immunity. This construct was introduced into the field of language teaching to delineate language teachers’ psychological state. Productive teacher immunity is defined as
Abdolreza Khalili, Mohammad Zohrabi, Leila Dobakhti   +2 more
doaj   +1 more source

أثر التدريب على مهارات التعلم الاجتماعي الوجداني في تعزيز المناعة النفسية وخفض الاحتراق المهني لدى معلمات رياض الأطفال The Effect of Training on Social-Emotional Learning Skills in Enhancing Psychological Immunity and Reducing Occupational Burnout among Kindergarten Teachers [PDF]

Maǧallaẗ Al-I'ršād Al-Nafsī
المستخلص: يهدف البحث الحالي إلى استكشاف أثر مهارات التعلم الاجتماعي الوجداني في تعزيز المناعة النفسية وخفض الاحتراق المهني لدى عينة من معلمات رياض الأطفال بمحافظة الإسماعيلية، من خلال تصميم وإعداد برنامج تدريبي مقترح لتمية مهارات التعلم الاجتماعي ...
إسلام أنور عبد الغني
doaj   +1 more source

Identification of senescence‐related genes in Parkinson's disease reveals candidate therapeutic targets and pathological processes

Animal Models and Experimental Medicine, EarlyView.
At the genomic level, a large number of differentially expressed genes (DEGs) and aging‐related DEGs have been screened. Ten hub genes, such as IFNγ and IRF7, have been identified and shown potential value in the diagnosis of PD, holding promise as novel biomarkers to facilitate early and precise diagnosis.
Haojie Wu, Tingting Liu, Xiangshu Cheng, Jianshe Wei   +3 more
wiley   +1 more source

A Causal Model of the Mutual Relationships Between Academic Bullying, Suicidal Thinking, and Psychological Immunity Among University Students

, 2021
The research aims to identify the causal model that explains the relationship between academic bullying, psychological immunity, and suicidal thinking among university students. Besides, it recognizes gender differences in research variables.
Hassan, Amani Abdel-Tawab Saleh
core  

A Mouse Model of Depression‐Tumor Multimorbidity Reveals the Mechanism of Tumor Growth Accelerated by Depression

Animal Research and One Health, EarlyView.
Depression accelerates tumor growth by dysregulation of tumor immune microenvironment. (A) Modeling methods: Subcutaneous tumor models were established under chronic unpredictable mild stress conditions, including cold swimming, physical restraint, and food/water deprivation, leading to increased tumor growth.
Yakun Ren, Xinpei Wang, Wen Wang, Xingjiu Yang, Mengyuan Li, Jing Du, Ran Gao   +6 more
wiley   +1 more source

Integrated Clinical and Proteomic Profiling of CD19 Chimeric Antigen Receptor T Cell Therapy in Progressive Systemic Sclerosis

Arthritis &Rheumatology, EarlyView.
Objective To characterize the clinical, immunologic, and proteomic changes associated with CD19 chimeric antigen receptor T cell therapy in patients with progressive systemic sclerosis (SSc). Methods Patients with progressive SSc received CD19 chimeric antigen receptor (CAR)‐T cell therapy and were observed longitudinally for safety, clinical efficacy,
Chenhan Jia, Wanyi Lin, Zhangyi Zhao, Fenglin Wu, Chaoyu Gu, Yuankai Sun, Zhe Ding, Chang Wei, Xinyu Li, Cuiwei Xie, Peng Xia, Zhen Xia, Xuesong Liu, Shaoying Yang, Chunyan Zhang, Hanlin Yin, Liangjing Lu   +16 more
wiley   +1 more source