Results 131 to 140 of about 8,790,753 (253)
O objetivo do estudo foi verificar a prevalência da síndrome de fragilidade e sua relação com a capacidade e o desempenho funcional em idosos frequentadores de grupos de convivência. O perfil de fragilidade foi determinado por meio dos critérios perda de
Lygia Paccini Lustosa +4 more
doaj +1 more source
Abstract Background 22q11.2 deletion syndrome (22q11DS) is a multisystem genetic disorder associated with a significantly increased risk of early‐onset Parkinson's disease (EOPD). Management is challenging because psychiatric and cognitive comorbidities often limit advanced therapies such as deep brain stimulation (DBS). Cases We report 2 patients with
Valle Victor Andrés +10 more
wiley +1 more source
Aim and Background: The purpose of this study was to investigate the effect of perceptual-motor exercises intervention on movement detection and motor coordination among aged women. Methods and Materials: In this semi-experimental study, 19 elderly women
مرتضی طاهری +3 more
doaj
Abstract Progressive supranuclear palsy is a rare and rapidly progressive neurodegenerative syndrome. Clinical manifestations are heterogeneous and include Parkinsonism, postural instability, oculomotor dysfunction and cognitive impairment, with 80% of patients progressing to dementia within 3 years. Cognitive impairment is consistently associated with
Timothy P. Siejka +4 more
wiley +1 more source
Abstract Background Long‐read sequencing and multi‐omic analytical frameworks are increasingly being adopted in rare disease diagnostics. However, clinical workflows comprehensively integrating these methodologies remain uncommon. Objective This study aimed to assess the potential and limitations of integrating long‐read genomic, transcriptomic, and ...
Ugo Sorrentino +23 more
wiley +1 more source
Regional Mitochondrial Density Maps Selective Posterior Atrophy in Parkinson's Disease
Abstract Background Mitochondrial dysfunction has been implicated in the pathobiology of Parkinson's disease (PD), yet the spatial relationship between regional energetic demand and patterns of neurodegeneration remains poorly understood, limiting mechanistic insight and development of disease‐modifying therapies.
Ajay Konuri +7 more
wiley +1 more source
This narrative review examines the neurological adverse effects associated with commonly used H1‐antihistamines, focusing on how blood–brain barrier (BBB) penetration and patient age influence central nervous system (CNS) toxicity. The major finding is that first‐generation antihistamines, because of higher CNS penetration, are associated with ...
Syeda Samia Fatima +6 more
wiley +1 more source
Long‐term chronic high‐altitude hypobaric hypoxia increases susceptibility to ICH, particularly among migrant populations lacking EPAS1/SENP1 adaptive genetic variants relative to high‐altitude indigenous residents. Persistent hypoxia initiates blood–brain barrier (BBB) breakdown, aberrant glial and immune activation, and progressive neuronal injury ...
Rongsu Huang +6 more
wiley +1 more source
Cheng M-Y, Wang K-P, Koester D, Hung T-M, Schack T. Proficient brain activity in superior golf putting performance: An insight from the EEG and psychomotor efficiency.
Cheng, M-Y +4 more
core +1 more source
Helena Gunnarsson,1,2 Birgitta Grahn,3–5 Jens Agerström1 1Department of Psychology, Faculty of Health and Life Sciences, Linnaeus University, Vaxjo, 2Hälsoringen, Neron HSU AB, Osby, 3Department of Clinical Sciences Lund-Orthopedics, Lund
Grahn B, Agerström J, Gunnarsson H
core

