Ethno-psychopharmacology [PDF]
How we judge in what way, with what potential side-effects, our patients respond to medications designed to help them recover from their psychiatric disorders is informed by experience, scientific knowledge and guesswork. The rapid movement of populations around the world, usually voluntary but sometimes driven by other motives or exigencies, means ...
openaire +2 more sources
Stressor- and Corticotropin releasing Factor-induced Reinstatement and Active Stress-related Behavioral Responses are Augmented Following Long-access Cocaine Self-administration by Rats [PDF]
Rationale Stressful events during periods of drug abstinence likely contribute to relapse in cocaine-dependent individuals. Excessive cocaine use may increase susceptibility to stressor-induced relapse through alterations in brain corticotropin-releasing
AM Basso +62 more
core +2 more sources
Reduction in Phencyclidine Induced Sensorimotor Gating Deficits in the Rat Following Increased System Xc − Activity in the Medial Prefrontal Cortex [PDF]
Rationale: Aspects of schizophrenia, including deficits in sensorimotor gating, have been linked to glutamate dysfunction and/or oxidative stress in the prefrontal cortex. System xc −, a cystine–glutamate antiporter, is a poorly understood mechanism that
A Araque +81 more
core +2 more sources
Implementation of gatekeeper training programs for suicide prevention in Japan: a systematic review
Background Suicide is a critical global health issue. Japan has had a high suicide rate for the last 12 decades. In 2007, the Japanese Central Government Office issued the “General Principles of Suicide Prevention Policy”.
Naohiro Yonemoto +3 more
doaj +1 more source
Cocaine Addiction as a Homeostatic Reinforcement Learning Disorder [PDF]
Drug addiction implicates both reward learning and homeostatic regulation mechanisms of the brain. This has stimulated 2 partially successful theoretical perspectives on addiction.
Durand, A. +4 more
core +1 more source
Mice haploinsufficient for Map2k7, a gene involved in neurodevelopment and risk for schizophrenia, show impaired attention, a vigilance decrement deficit and unstable cognitive processing in an attentional task: impact of minocycline [PDF]
Rationale: Members of the c-Jun N-terminal kinase (JNK) family of mitogen-activated protein (MAP) kinases, and the upstream kinase MKK7, have all been strongly linked with synaptic plasticity and with the development of the neocortex.
Morris, B.J. +4 more
core +1 more source
Abstract Growing evidence supports the efficacy of various psychosocial interventions yet provides very little information about the potential harms and burdens of treatment. Lacking such information makes it difficult to make truly informed decisions about treatment options.
Raquel W. Halfond +2 more
wiley +1 more source
Sex influences the brain functional connectivity correlates of originality
Creative cognition is thought to involve two processes, the creation of new ideas and the selection and retention of suitable new ideas. Neuroimaging studies suggest that the Default Mode Network contributes to the creation of new ideas while left ...
Richard B. Silberstein +1 more
doaj +1 more source
Analysis on the current situation and reform strategies of psychopharmacology course
The purpose of this paper is to optimize the course construction and teaching process of psychopharmacology, and analyze the problems in the course of teaching and assessment of psychopharmacology from many aspects. This article is to deeply excavate the
Guo Fei +6 more
doaj +1 more source
Everyday and prospective memory deficits in ecstasy/polydrug users [PDF]
The impact of ecstasy/polydrug use on real-world memory (i.e. everyday memory, cognitive failures and prospective memory [PM]) was investigated in a sample of 42 ecstasy/polydrug users and 31 non-ecstasy users. Laboratory-based PM tasks were administered
Bridges, Nikola +7 more
core +1 more source

