Results 141 to 150 of about 19,645 (222)

AI Alignment Versus AI Ethical Treatment: 10 Challenges

Analytic Philosophy, EarlyView.
ABSTRACT A morally acceptable course of AI development should avoid two dangers: creating unaligned AI systems that pose a threat to humanity and mistreating AI systems that merit moral consideration in their own right. This paper argues these two dangers interact and that if we create AI systems that merit moral consideration, simultaneously avoiding ...
Adam Bradley, Bradford Saad
wiley   +1 more source

How do physiological networks respond to normobaric hypoxia and isometric exercise?

Experimental Physiology, EarlyView.
Abstract The dynamics of physiological systems are impacted by both exercise and hypoxia. Network models can be used to map the interactions between various physiological components in environmental physiology and exercise using the concepts of information theory.
Danilo Bondi, Cecilia Morandotti, Salvatore Annarumma, Carmen Santangelo, Tiziana Pietrangelo, Stefania Fulle, Vittore Verratti   +6 more
wiley   +1 more source

Transition rates to schizophrenia and early intervention effectiveness in substance-induced and brief psychotic disorders: a randomized controlled trial. [PDF]

Sci Rep
Abouzed M, Gabr A, Elsheikh M, Elag KA, Zeid MY, Barakat M, Elasaly E, Elsaadouni N, Soliman M.   +8 more
europepmc   +1 more source

“Keys to Words that are already there”: Chief Bromden’s Psychedelic Journey towards Redemption [PDF]

, 2016
Besbes, Mongia
core  

Disruption of the l‐DOPA Receptor Gpr143/OA1‐Gene in Mice Creates a Unique Mixed Psychosis‐Like Phenotype

Neuropsychopharmacology Reports, Volume 46, Issue 1, March 2026.
We analyzed the behavior of GPR143 gene‐deficient mice. GPR143‐KO mice displayed a mixed psychiatric phenotype. GPR143 may play a role in mesolimbic and mesocortical functions underlying sensory gating, reward, social hierarchy, cognition, and emotional regulation. ABSTRACT GPR143, originally identified as the gene product of ocular albinism 1 (OA1), a
Yoshio Goshima, Haruko Nakamura, Motokazu Koga, Junka Koyama, Yayoi Kimura, Maya N. Vasishth, Evan Y. Snyder, Masashi Asai, Kenta Sakai, Daiki Masukawa   +9 more
wiley   +1 more source

Cocaine Induced Postictal Psychosis: a Rare Cause of Antipsychotic Resistant Psychosis. [PDF]

Hawaii J Health Soc Welf
Chang AN, Kiyokawa M, Grysman N.
europepmc   +1 more source

Restoring decision‐making capacity through ECT to enable clozapine initiation in treatment‐resistant schizophrenia: An ethical and clinical case report

Psychiatry and Clinical Neurosciences Reports, Volume 5, Issue 1, March 2026.
Abstract Background Treatment‐resistant schizophrenia (TRS) is often accompanied by poor insight and impaired decision‐making capacity (DMC), complicating the initiation of clozapine (CLZ) despite clear clinical indications. In Japan, CLZ utilization is markedly lower than in many foreign countries, partly due to concerns about adverse effects ...
Shimpei Hanaoka, Hiroki Suzuki, Akira Sugeno   +2 more
wiley   +1 more source

A case of diverse psychiatric and functional impairments following immune checkpoint inhibitor therapy

Psychiatry and Clinical Neurosciences Reports, Volume 5, Issue 1, March 2026.
Abstract Background Immune checkpoint inhibitors (ICIs) can cause a range of immune‐related adverse events (irAEs), including rare neuropsychiatric complications. However, these events often present with diverse and non‐specific symptoms, making diagnosis difficult.
Takako Ikegami, Ryoichi Sadahiro, Junji Yamaguchi, Eri Nishikawa, Saho Wada, Tatsuto Terada, Rika Nakahara, Hiromichi Matsuoka   +7 more
wiley   +1 more source

Mental automatism and exogenous psychosis: the originality of De Clérambault's and Karl Bonhoeffer's theories in substance-related psychoses. [PDF]

Front Psychiatry
Ricci V, Sarni A, Maina G.
europepmc   +1 more source

Esketamine/Ketamine: Dual‐Action Mechanisms and Clinical Prospects beyond Anesthesia in Psychiatry, Immunology, and Oncology

Advanced Science, Volume 13, Issue 7, 3 February 2026.
Esketamine and ketamine are widely used for perioperative analgesia and anesthesia. Despite their established roles in analgesia, sedation, and anesthesia, as well as emerging antidepressant, anti‐tumor, and anti‐inflammatory effects, their clinical use is limited due to side effects and addiction potential.
Yinxin Wang, Jiangang Xu, Xinyu Zhou, Lu Che, Minghan Qiu, Yang Liu, Ming Gao, Zhen Yang   +7 more
wiley   +1 more source