Results 151 to 160 of about 19,768 (236)

Axon Initial Segment: Structure, Biological Functions, Diseases, and Therapeutic Targets

MedComm, Volume 7, Issue 4, April 2026.
The axon initial segment (AIS) is a specialized axonal domain critical for maintaining neuronal polarity, action potential initiation, and network stability. This review summarizes the necessary elements for maintaining AIS structure and plasticity, discussing crucial biological functions of AIS in neuronal signaling and the neural circuit homeostasis,
Dong‐Yan Song, Lin Yuan, Weiguo Yang, Wen Li, Jia‐Yi Li   +4 more
wiley   +1 more source

Mas‐Related G Protein‐Coupled Receptor Member D Sustains Hypertension

MedComm, Volume 7, Issue 4, April 2026.
Targeting MrgD attenuated hypertension and alleviated hypertension‐associated vascular remodeling via repressing Cav1.2‐CaMKIIγ axis. Risperidone, a small‐molecule inhibitor of MrgD, could alleviate hypertension and artery remodeling induced by Ang II infusion.
Kun Zhao, Dongxu Hua, Yukang Mao, Xiaoguang Wu, Min Gao, Shidong Song, Lei Chen, Xiangxiang Zheng, Peng Li   +8 more
wiley   +1 more source

Drug-induced mania and parkinsonism in substance use disorder patient: A case report. [PDF]

Indian J Pharmacol
Gurumoorthi R, Rajendran RS, Murugan A, Thiyagarajan K, Rajanandh MG.   +4 more
europepmc   +1 more source

Attitudes Toward Injectable GLP‐1 Drugs for Obesity Treatment: A Qualitative Interview Study With Healthcare Professionals

Obesity Science &Practice, Volume 12, Issue 2, April 2026.
ABSTRACT Background Injectable GLP‐1 drugs such as semaglutide (Wegovy) and tirzepatide (Mounjaro, a dual GLP‐1 and GIP receptor agonist) can help individuals living with obesity to lose weight. UK guidelines currently recommend semaglutide and other injectable GLP‐1 drugs are prescribed in specialist (Tier 3) multidisciplinary weight management ...
Raluca C. Capaian, Phillippa Lally, Saskia C. Sanderson   +2 more
wiley   +1 more source

Computer‐Assisted Performance‐Based Assessment for Mental Health: A Scoping Review

PsyCh Journal, Volume 15, Issue 2, April 2026.
ABSTRACT Adolescent mental health is foundational to personal development, yet it faces escalating challenges globally. While traditional assessment methods lack objectivity and ecological validity, integrating computer‐assisted technology (CAT) into performance‐based assessments (PBAs) offers a promising pathway.
Hanya Li, Shuang Li
wiley   +1 more source

Mental automatism and exogenous psychosis: the originality of De Clérambault's and Karl Bonhoeffer's theories in substance-related psychoses. [PDF]

Front Psychiatry
Ricci V, Sarni A, Maina G.
europepmc   +1 more source

Altered Brain Tissue Volumes With Valproate Treatment for Schizophrenia

Journal of the Royal Society of New Zealand, Volume 56, Issue 2, April 2026.
Schizophrenia is a debilitating psychiatric condition that affects ≈0.5% of the global population. Some people with schizophrenia do not respond to first‐line antipsychotics and are prescribed clozapine; this is termed treatment‐resistant schizophrenia (TRS).
Thomas Cawood, Olivia K. Harrison, Meghan McIlwain, Robert R. Kydd, Bruce R. Russell   +4 more
wiley   +1 more source

Is Addiction Research Addicted to Artificial Intelligence? Mapping the Intersection of Artificial Intelligence, Substance Use and Mental Health Through a Bibliometric Analysis. [PDF]

Drug Alcohol Rev
Vanhée L, Scarpa S.
europepmc   +1 more source

An Underrecognized Problem: Missed and Delayed Carbidopa‐Levodopa Administration in Emergency Department Patients With Parkinson's Disease

Academic Emergency Medicine, Volume 33, Issue 4, April 2026.
ABSTRACT Introduction Patients with Parkinson's disease (PD) frequently present to the Emergency Department (ED). Whether for PD‐related complications or unrelated concerns, maintaining their antiparkinsonian medication regimen without interruption is crucial. Delays or omissions can lead to significant morbidity and mortality.
Natalie M. Elder, Erica M. Lash, Christopher Tomkins‐Tinch   +2 more
wiley   +1 more source

Acute mania and psychosis potentially triggered by St John's wort. [PDF]

PCN Rep
Yoshioka D, Yamanashi T, Iwata M.
europepmc   +1 more source