Results 131 to 140 of about 134,407 (301)
CYP2C19 Genotype is Associated with Citalopram Treatment Outcomes in a Real‐World Setting
Clinical Pharmacology &Therapeutics, EarlyView.CYP2C19 metabolizes various selective serotonin reuptake inhibitors (SSRIs) and genetic CYP2C19 variants are associated with SSRI tolerability and response. Yet, whether CYP2C19 variability also impacts citalopram response remained unclear. We here evaluated associations between CYP2C19 genotypes and citalopram prescription data of 11,079 patients from
Yoomi Park +2 more
wiley +1 more source
Consideraciones para un retorno al concepto de deseo en la clínica analítica de las psicosis
Psicologia USPResumen El artículo propone discutir la relativa ausencia de referencias al concepto de deseo psicótico dentro de la comunidad lacaniana. El debate es de relevancia ya que Lacan no excluyó al deseo y tampoco a las psicosis de su concepción de la cura ...
Julieta De Battista
doaj +1 more source
Clinical Pharmacology &Therapeutics, EarlyView.Risperidone is a commonly used antipsychotic for treating psychiatric illness in children and adolescents. There is a large variability in risperidone response and discontinuation rates remain high. Pharmacogenomics offers the opportunity to improve risperidone outcomes, yet studies in pediatric populations are limited.
Jack W. Staples +10 more
wiley +1 more source
Current practices in managing acutely disturbed patients at three hospitals in Rio de Janeiro-Brazil: a prevalence study [PDF]
, 2002 The medical management of aggressive and violent behaviour is a critical situation for which there is little evidence. In order to prepare for a randomised trial, due to start in the psychiatric emergency rooms of Rio de Janeiro in 2001, a survey of ...
Adams, C.E. +8 more
core
Registered Clinical Trials of Ayahuasca and DMT: A Scoping Review
Clinical Pharmacology &Therapeutics, EarlyView.Interest in ayahuasca and its main component, N,N‐Dimethyltryptamine (DMT), has currently moved from historical and experimental use into modern clinical development. Yet, current evidence is fragmented, and systematic mapping of trial methods and design choices remains limited.
Tijana Stojanović +4 more
wiley +1 more source
International Journal of Eating Disorders, EarlyView.ABSTRACT Objective Anorexia nervosa (AN) is a severe psychiatric disorder marked by an intense fear of gaining weight and persistent body dissatisfaction, both during periods of underweight and after weight restoration. The endocannabinoid system may offer therapeutic benefits, particularly in reducing anxiety.
Neha Sahota +8 more
wiley +1 more source
Synthesis and D2-like binding affinity of new derivatives of N3-[(1- ethyltetrahydro-1H-2-pyrrolyl)methyl]-4,5-dihydrobenzo[g]indole-3- carboxamide and related compounds [PDF]
, 2000 In previous papers 4a,b we have reported the syntheses and structure-activity relationships of a series of 5-phenyl-3-pyrrole carboxamide and related 4,5-dihydrobenzo[g]indole-3-carboxamide analogues whose most representative terms were 1a and 2a ...
Chelucci, Giorgio Adolfo +5 more
core
International Journal of Eating Disorders, EarlyView.ABSTRACT Objective Inpatient treatment aimed at weight restoration and psychiatric stabilization is often required for individuals with anorexia nervosa (AN). This study aimed to identify distinct trajectories of change in body mass index (BMI) and depressive symptoms during inpatient treatment, examine clinical predictors and outcomes, and test ...
Matteo Martini +5 more
wiley +1 more source
International Journal of Eating Disorders, EarlyView.ABSTRACT Objective Eating disorders (EDs) are severe and complex psychiatric illnesses, with adolescence and young adulthood representing particularly vulnerable periods for onset, relapse and disruptions in treatment. The transition from Child and Adolescent Mental Health Services (CAMHS) to Adult Mental Health Services (AMHS) is especially complex ...
Maria Livanou +19 more
wiley +1 more source