Results 161 to 170 of about 134,407 (301)

Disrupted Brain Structure and Function in Alzheimer's Disease Patients With Behavioral and Psychological Symptoms

iNew Medicine, EarlyView.
ABSTRACT Behavioral and psychological symptoms of dementia (BPSD) are highly prevalent in Alzheimer's disease (AD), but the underlying mechanisms are unclear. This study aims to elucidate the neuropathological mechanisms underlying BPSD by investigating gray matter volume (GMV) and brain connectivity in AD patients with and without BPSD.
Xuerui Pang, Linbo Xie, Mengdan Chen, Yi Ji, Yibing Yan, Shanshan Zhou, Panpan Hu, Xingqi Wu, Kai Wang   +8 more
wiley   +1 more source

Depression and psychotic disorders worsen perioperative outcomes and increase resource utilization after multilevel lumbar fusion: Implications for screening and perioperative care. [PDF]

J Craniovertebr Junction Spine
Mastrokostas LE, Mastrokostas PG, Schwartz LB, Razi A, Inzerillo S, Houten JK, Varthi A, Vaccaro AR, Monsef JB, Razi AE, Ng MK.   +10 more
europepmc   +1 more source

Complement C3 mediates adolescent social isolation‐induced hippocampal synaptic deficits and sex‐specific emotional dysfunction

Interdisciplinary Medicine, EarlyView.
Adolescent social isolation disrupts hippocampal function and exacerbates emotional symptoms, with sex‐specific patterns, as shown by human studies. In mice, social isolation decreased hippocampal synaptic density and calcium signaling, upregulated complement proteins, and activated complement‐mediated microglial synaptic phagocytosis.
Yuwan Qi, Siying Weng, Qiao Yin, Mengqi Li, Liang Shen, Enyou Qiao, Lu Gao, Yihan Wang, Yuxuan Li, Weifeng Luo, Qilin Zhang, Jing Wang, Jianfeng Feng, Qifei Cong   +13 more
wiley   +1 more source

PEPAMARKER: a multicenter cohort study protocol on predictive biomarkers of affective vs. non-affective trajectories in first-episode psychosis. [PDF]

Front Psychiatry
Terrisse R, Lemey C, Kim-Dufor DH, Miglianico L, Stéphan F.   +4 more
europepmc   +1 more source

The We‐Relationship as a Key to Addressing Dementia‐Related Ambiguous Loss

Journal of Applied Philosophy, EarlyView.
ABSTRACT Pauline Boss describes the challenges faced by people caring for family members with dementia in terms of ambiguous loss – a condition in which the physical presence of the person with dementia coexists with their psychological absence. This article proposes the concept of we‐relationship as a key to addressing dementia‐related ambiguous loss.
Takuya Niikawa, Xue Li
wiley   +1 more source

Substance-Specific Treatment Responses and Resistance Patterns in Induced Psychoses: A Scoping Review of Antipsychotic Efficacy. [PDF]

Healthcare (Basel)
Ricci V, Chiappini S, Martinotti G, Maina G.   +3 more
europepmc   +1 more source

Understanding Autistic Young Adults' Perceptions and Experiences of Traumatic and Stressful Events

Journal of Clinical Psychology, Volume 81, Issue 6, Page 445-461, June 2025.
ABSTRACT Objectives The aim of this study was to explore how young autistic adults experience and respond to stressful life events, and the relationship between autistic characteristics and symptoms of stress associated with these events. Methods Using an exploratory sequential mixed‐methods approach, an online qualitative survey was first administered
Alliyza Lim, Robyn L. Young
wiley   +1 more source

Differential Impact of Depression and Psychotic Disorders on Complications, Costs, and Discharge After Single-Level Lumbar Fusion. [PDF]

Global Spine J
Ng MK, Mastrokostas LE, Mastrokostas PG, Baek G, Dalton J, Fano A, Giakas A, Singh R, Razi AE, Varthi A, Kurd MF, Wilt Z, Fassett DR, Hilibrand AS, Vaccaro AR, Schroeder GD, Kepler CK, Alvarez AP.   +17 more
europepmc   +1 more source

Using Virtual Reality Social Environments to Promote Outcomes' Generalization of AVATAR Therapy for Distressing Voices: A Case Study

Journal of Clinical Psychology, Volume 81, Issue 6, Page 516-525, June 2025.
ABSTRACT AVATAR therapy (AT) works by facilitating a ‘face‐to‐face’ dialog between the person and a digital representation (avatar) of their persecutory voice. Although there is cumulative evidence of this way of working with voices, enhancing the therapeutic focus on improved confidence and a sense of control of the voices in social situations ...
Mar Rus‐Calafell, Nils Ehrbar, Tobias Teismann, Silvia Schneider, Ekincan Tas, Simon Schuster, Clementine Edwards, Mark Huckvale, Thomas Craig, Philippa Garety, Thomas Ward   +10 more
wiley   +1 more source

Prevalence of schizophrenia spectrum and bipolar disorder among patients with cannabis induced psychosis: a systematic review and meta-analysis. [PDF]

BMC Psychiatry
Javed MS, El-Khoury R, Taha AA, Reagu SM.   +3 more
europepmc   +1 more source