Don’t turn your back on the symptoms of psychosis : a proof-of-principle, quasi-experimental public health trial to reduce the duration of untreated psychosis in Birmingham, UK [PDF]
Background: Reducing the duration of untreated psychosis (DUP) is an aspiration of international guidelines for first episode psychosis; however, public health initiatives have met with mixed results.
A Malla +32 more
core +4 more sources
Reading emotions from body movement: a generalized impairment in schizophrenia
Body language reading is a social cognitive process with importance for successful maneuvering of social situations. In this study, we investigated body language reading as assessed with human point-light displays in participants with a diagnosis of ...
Anja eVaskinn +11 more
doaj +1 more source
Introduction N-Methyl-D-Aspartate Receptor (NMDAR) hypofunction is hypothesised to underlie psychosis but this has not been tested early in illness. Objectives Our aim was to determine if NMDAR availability was lower in patients with first episode ...
K. Beck +8 more
doaj +1 more source
Psychotic symptoms are rarely documented in association with cortex-sparing central nervous system (CNS) lesions limited to the midbrain. We present the case of a 15-year-old boy with hereditary and environmental risk factors for psychiatric illness, as well as a history of midbrain pilocytic astrocytoma treated with chemotherapy and focused radiation,
John Paul Andrews +3 more
openaire +2 more sources
Negative cognition, affect, metacognition and dimensions of paranoia in people at ultra-high risk of psychosis: a multi-level modelling analysis [PDF]
Background: Paranoia is one of the commonest symptoms of psychosis but has rarely been studied in a population at risk of developing psychosis. Based on existing theoretical models, including the proposed distinction between ‘poor me’ and ‘bad me ...
Bentall, R.P. +10 more
core +2 more sources
Alterations in cortical inter-areal functional connectivity, and aberrant glutamatergic signalling are implicated in the pathophysiology of schizophrenia but the relationship between the two is unclear.
Robert A. McCutcheon +4 more
doaj +1 more source
Uncharted Waters: Treating Trauma Symptoms in the Context of Early Psychosis. [PDF]
Psychosis is conceptualized in a neurodevelopmental vulnerability-stress framework, and childhood trauma is one environmental factor that can lead to psychotic symptoms and the development of psychotic disorders.
B Folk, Johanna +7 more
core +1 more source
Recently evolved human-specific methylated regions are enriched in schizophrenia signals
Background One explanation for the persistence of schizophrenia despite the reduced fertility of patients is that it is a by-product of recent human evolution.
Niladri Banerjee +6 more
doaj +1 more source
Transition to Psychosis in Individuals at Clinical High Risk: Meta-analysis
Introduction Estimating the current likelihood of transitioning from a clinical high risk for psychosis (CHR-P) to psychosis holds paramount importance for preventive care and applied research.
G. Salazar De Pablo +7 more
doaj +1 more source
Recovery from psychosis : physical health, antipsychotic medication and the daily dilemmas for mental health nurses [PDF]
This paper considers some of the dilemmas experienced by Mental Health Nurses everyday when faced with the seemingly conflicting relationships that exist between recovery, antipsychotics and the physical health of people experiencing psychosis.
Bressington, D. +3 more
core +1 more source

