Results 61 to 70 of about 250,129 (223)

Aberrant High-Order Dependencies in Schizophrenia Resting-State Functional MRI Networks [PDF]

arXiv, 2023
The human brain has a complex, intricate functional architecture. While many studies primarily emphasize pairwise interactions, delving into high-order associations is crucial for a comprehensive understanding of how functional brain networks intricately interact beyond simple pairwise connections.
arxiv  

Beyond the dopamine hypothesis of schizophrenia to three neural networks of psychosis: dopamine, serotonin, and glutamate

CNS Spectrums, 2018
Psychosis is now widely hypothesized to involve neural networks beyond the classical dopaminergic mesolimbic pathway, including serotonin and glutamate systems as well.
S. Stahl
semanticscholar   +1 more source

Lonely in a crowd: investigating the association between overcrowding and loneliness using smartphone technologies

Scientific Reports, 2021
Loneliness is a major public health concern with links to social and environmental factors. Previous studies have typically investigated loneliness as a stable emotional state using retrospective cross-sectional designs.
Ryan Hammoud, Stefania Tognin, Ioannis Bakolis, Daniela Ivanova, Naomi Fitzpatrick, Lucie Burgess, Michael Smythe, Johanna Gibbons, Neil Davidson, Andrea Mechelli   +9 more
doaj   +1 more source

A single-blind, randomised controlled trial of a physical health nurse intervention to prevent weight gain and metabolic complications in first-episode psychosis: the Physical Health Assistance in Early Psychosis (PHAstER) study

BJPsych Open, 2022
Background Factors that contribute to the early mortality observed in psychotic disorders, specifically obesity, smoking and sedentary behaviour, occur early in the disorder.
Brian O'Donoghue, Nathan Mifsud, Emily Castagnini, Alison Langstone, Andrew Thompson, Eoin Killackey, Patrick McGorry   +6 more
doaj   +1 more source

A comprehensive protocol for manual segmentation of the human claustrum and its sub-regions using high-resolution MRI [PDF]

arXiv, 2020
The claustrum (Cl) is a thin grey matter structure located in the center of each brain hemisphere. Cl has been hypothesized as a central hub of the brain for multisensory/sensorimotor integration, consciousness, and attention. Accumulating evidence has suggested that Cl might be important in the development of severe neurological and psychiatric ...
arxiv  

The effect of training intensity on implicit learning rates in schizophrenia

Scientific Reports, 2021
Cognitive impairments in learning and memory are core symptoms of schizophrenia, associated with reduced self-reported quality of life. The most effective treatment of cognitive impairments is drill and practice cognitive training.
Natasza D. Orlov, Jessica Sanderson, Syed Ali Muqtadir, Anastasia K. Kalpakidou, Panayiota G. Michalopoulou, Jie Lu, Sukhi S. Shergill   +6 more
doaj   +1 more source

Lack of evidence to favor specific preventive interventions in psychosis: a network meta‐analysis

World Psychiatry, 2018
Preventing psychosis in patients at clinical high risk may be a promising avenue for pre‐emptively ameliorating outcomes of the most severe psychiatric disorder.
C. Davies, A. Cipriani, J. Ioannidis, J. Raduà, D. Ståhl, U. Provenzani, P. McGuire, P. Fusar-Poli   +7 more
semanticscholar   +1 more source

Biological Predictors of Clozapine Response: A Systematic Review

Frontiers in Psychiatry, 2018
Background: Clozapine is the recommended antipsychotic for treatment-resistant schizophrenia (TRS) but there is significant variability between patients in the degree to which clozapine will improve symptoms.
Ruta Samanaite, Amy Gillespie, Amy Gillespie, Kyra-Verena Sendt, Grant McQueen, James H. MacCabe, Alice Egerton   +6 more
doaj   +1 more source

Loneliness in Psychosis: A Meta-analytical Review

Schizophrenia bulletin, 2018
Loneliness may be related to psychotic symptoms but a comprehensive synthesis of the literature in this area is lacking. The primary aim of the current study is to provide a systematic review and meta-analysis of the association between loneliness and ...
Beata Michalska da Rocha, S. Rhodes, Eleni Vasilopoulou, P. Hutton   +3 more
semanticscholar   +1 more source

Heterogeneity of Psychosis Risk Within Individuals at Clinical High Risk: A Meta-analytical Stratification.

JAMA psychiatry, 2016
IMPORTANCE Individuals can be classified as being at clinical high risk (CHR) for psychosis if they meet at least one of the ultra-high-risk (UHR) inclusion criteria (brief limited intermittent psychotic symptoms [BLIPS] and/or attenuated psychotic ...
P. Fusar-Poli, M. Cappucciati, S. Borgwardt, S. Woods, J. Addington, B. Nelson, D. Nieman, D. Ståhl, G. Rutigliano, A. Riecher-Rössler, A. Simon, M. Mizuno, Tae Young Lee, J. Kwon, M. Lam, Jesus Perez, S. Kéri, P. Amminger, S. Metzler, W. Kawohl, W. Rössler, Jimmy Lee, J. Labad, T. Ziermans, S. An, Chen-Chung Liu, K. Woodberry, A. Braham, C. Corcoran, P. McGorry, A. Yung, P. McGuire   +31 more
semanticscholar   +1 more source