Results 61 to 70 of about 381,820 (339)

Temporal trends in and associations with nonsteroidal anti‐inflammatory drug prescription in adult and pediatric patients with inflammatory bowel disease

Arthritis Care &Research, Accepted Article.
Objective Recent inflammatory bowel disease (IBD) treatment guidelines have recommended against NSAID use despite prevalent musculoskeletal symptoms and opioid overuse in this population. Given the discordance between changing national guidelines and potential clinical utility, we sought to assess national temporal trends in prescription NSAID and ...
Adam S. Mayer, Rui Xiao, Andrew Grossman, Meenakshi Bewtra, Michael D. George, Pamela F. Weiss   +5 more
wiley   +1 more source

Time‐Dependent Therapeutic Effect of S‐Ketamine on PTSD Mediated by VTA‐OFC Dopaminergic Neurocircuit

Advanced Science, EarlyView.
This study reveals that early rather than late administration of S‐ketamine can ameliorate PTSD symptoms. This phenomenon is attributed to reversing the progressive inhibition of VTADA neurons and the function of VTADA‐OFC circuit following stress. Targeted stimulation of the OFC by TI‐NIBS to enhance DA release effectively extends the therapeutic time
Ye Wang, Lei Liu, Jinghao Wang, Jiannan Li, Huiming Li, Rui Wang, Hui Wang, Min Wang, Quanying Liu, Zhongmin Fan, Yunyun Zhang, Xinxin Zhang, Dan Wang, Sa Wang, Rou Xue, Jindong Mao, Min Cai, Pengfei Wei, Hailong Dong, Yumei Wu, Guangchao Zhao   +20 more
wiley   +1 more source

Cognitive alterations in patients with non-affective psychotic disorder and their unaffected siblings and parents [PDF]

, 2012
Meijer J, Simons CJP, Quee PJ, Verweij K, GROUP Investigators. Cognitive alterations in patients with non-affective psychotic disorder and their unaffected siblings and ...
Addington, Andreasen, Anselmetti, Appels, Bediou, Benton, Bilder, Blyler, Bora, Brand, Broome, Ceaser, Cornblatt, Dickinson, Egan, Egeland, Genetic Risk and Outcome in Psychosis (GROUP) Investigators, Glass, Green, Greenwood, Gur, Heinrichs, Heinrichs, Jabben, Keefe, Keefe, Keefe, Kelemen, Keshavan, Kremen, Kremen, Kéri, Meiran, Miller, Morice, Nolan, Nuechterlein, Palmer, Palmer, Pukrop, Savla, Sergi, Sitskoorn, Snitz, Sprong, Thornton, Van Hooren, Van Os, Van‘T Wout, Vauth, Versmissen, Wechsler, Welham, Yücel   +53 more
core   +5 more sources

Successful clozapine re-challenge in a patient with three previous episodes of clozapine-associated blood dyscrasia

BJPsych Open, 2017
A case is presented of a 30-year-old female with treatment-resistant schizoaffective disorder who was referred to a tertiary-level specialist psychosis service.
Jessica Foster, John Lally, Victoria Bell, Sukhi Shergill   +3 more
doaj   +1 more source

Psychosis and Human Rights: Conflicts in Mental Health Policy and Practice [PDF]

, 2009
This paper examines conflicts in polices in England and Wales pertaining to the demand for alternative, non-medical crisis support for those experiencing ‘psychosis’.
Bentall, Clarke, Dwyer, Fernando, Gale, Gottstein, Helen Spandler, Hopper, Knight, May, Plumb, Rankin, Repper, Shepherd, Spandler, Stastny, Tim Calton, Vasak, Warner   +18 more
core   +1 more source

Genetic Evidence Supporting a Role for Brain Region Volume and Functional Network Alterations in Major Depression

Advanced Science, EarlyView.
Genome‐wide analyses indicate that reduced ventral diencephalon and thalamus volumes, along with decreased functional connectivity within the triple network (DMN/CEN/SN), are uniquely associated with the risk of major depression (MD) onset, compared to other similar severe psychiatric disorders.
Ming‐Min Xu, Nan Li, Yi‐Wen Lv, Wen‐Miao Yang, Zhi‐Yun Yu, Yi‐Min Zhang, Yu Guo, Xiao‐Yin Chen   +7 more
wiley   +1 more source

Remission with or without comorbid substance use disorders in early psychosis: long-term outcome in integrated care (ACCESS III study)

Frontiers in Psychology, 2023
IntroductionSchizophrenia-Spectrum-Disorders are associated with poor long-term outcome as well as disability and often severely affect the lives of patients and their families often from symptom onset. Up to 70% of first episode psychosis (FEP) patients
Friederike Rühl, Martin Lambert, Anja Rohenkohl, Vivien Kraft, Anne Daubmann, Brooke C. Schneider, Daniel Luedecke, Anne Karow, Jürgen Gallinat, Gregor Leicht, Daniel Schöttle   +10 more
doaj   +1 more source

Mindfulness for psychosis [PDF]

British Journal of Psychiatry, 2014
SummaryMindfulness treatments and research have burgeoned over the past decade. With psychosis, progress has been slow and likely held back by clinicians' belief that mindfulness may be harmful for this client group. There is emerging evidence that mindfulness for psychosis – when used in an adapted form – is safe and therapeutic.
openaire   +4 more sources

Allele‐Specific Regulation of PAXIP1‐AS1 by SMC3/CEBPB at rs112651172 in Psychiatric Disorders Drives Synaptic and Behavioral Dysfunctions in Mice

Advanced Science, EarlyView.
This study identifies a functional noncoding variant, rs112651172 (C/G), that drives allele‐specific expression of PAXIP1‐AS1 in monozygotic twin pairs discordant for schizophrenia and bipolar disorder. The risk G allele enhances CEBPB binding, leading to lncRNA upregulation, CNTNAP3 derepression, and synaptic and behavioral deficits in mice.
Chaoying Ni, He Chen, Qiaqi Chen, Yangyang Liao, Yunqian Wang, Linyan Ye, Xiaohui Wu, Hongyu Ni, Tingyun Jiang, Shufen Li, Qiong Yang, Hong Xue, Zhongju Wang, Feng Yi, Cunyou Zhao   +14 more
wiley   +1 more source

Ten year neurocognitive trajectories in first-episode psychosis

Frontiers in Human Neuroscience, 2013
Objective: Neurocognitive impairment is commonly reported at onset of psychotic disorders. However, the long-term neurocognitive course remains largely uninvestigated in first episode psychosis (FEP) and the relationship to clinically significant ...
Helene Eidsmo Barder, Helene Eidsmo Barder, Helene Eidsmo Barder, Kjetil eSundet, Kjetil eSundet, Bjørn eRund, Bjørn eRund, Julie eEvensen, Julie eEvensen, Ulrik eHaahr, Wenche eHegelstad, Inge eJoa, Jan Olav eJohannessen, Jan Olav eJohannessen, Johannes eLangeveld, Tor Ketil eLarsen, Tor Ketil eLarsen, Ingrid eMelle, Ingrid eMelle, Stein eOpjordsmoen, Stein eOpjordsmoen, Jan Ivar eRøssberg, Jan Ivar eRøssberg, Erik eSimonsen, Per eVaglum, Thomas eMcGlashan, Svein eFriis, Svein eFriis   +27 more
doaj   +1 more source