Results 61 to 70 of about 241,274 (304)

A validation of a new measure of activity in psychosis [PDF]

, 2006
Despite demonstrated relationships between activity and clinical change, we lack effective measures of time use in psychosis. Existing time budget measures of activity are demanding to complete, and thus unsuited to routine clinical use as measures of ...
Garety, PA, Dunn, Graham, Bebbington, P E, Freeman, D, Dunn, G., Dunn, G, Bebbington, PE, Jolley, S., Bebbington, P.E., Garety, P A; id_orcid, Ellett, L, Kuipers, E; id_orcid, Kuipers, Elizabeth, Fowler, DG, Garety, Philippa A., Fowler, G., Fowler, D G, Kuipers, E, Garety, P.A., Fowler, David G., Bebbington, Paul E., Freeman, D., Freeman, Daniel, Jolley, Suzanne, Jolley, S, Ellett, Lyn, Kuipers, E.   +26 more
core   +1 more source

A Gut‐Brain Axis Underlying Succinate‐Associated Compulsive‐Like Behavior

Advanced Science, EarlyView.
Gut‐derived succinate is associated with an excitatory‐inhibitory imbalance in dmPFC glutamatergic neurons, involving microglial SUCNR1 activation and vagal afferent signaling via upregulated gut 5‐HT4 receptors along the DVC‐CeA‐dmPFC circuit, changes that are linked to excessive compulsive‐like behavior.
Yi Li, Ying‐Dan Zhang, Wei Wang, Xin‐Yi Wu, Di Li, Xin Gong, Fei Tian, Meng‐Yu Dai, Jian Gao, Zi‐Feng Zheng, Zi‐Yang Bi, Dong‐Dong Shi, Zhen Wang   +12 more
wiley   +1 more source

PSYCHOSIS OF MORPHINISM. [PDF]

JAMA: The Journal of the American Medical Association, 1905
All writers have mentioned the general defective conception of truth and the relation of right and wrong which appears to be a prominent symptom in all persons who use morphia. It is difficult to understand whether this is a veritable paralysis of the higher reasoning centers or a defect of the senses by which distorted conceptions of facts are not ...
openaire   +2 more sources

Protocol for a systematic review and meta-analysis of cognitive-behavioural therapy for social anxiety disorder in psychosis [PDF]

, 2014
Background: Social anxiety is among the most prevalent and debilitating affective disturbances manifest in people with psychosis. It is usually accompanied by high levels of depression and leads to significant social disability, lower quality of life ...
Michail, M.; id_orcid, Max Birchwood, Michail, Maria, Maria Michail, Lynda Tait, Birchwood, M., Tait, L., Birchwood, M. J., Tait, Lynda   +8 more
core   +2 more sources

Ten year neurocognitive trajectories in first-episode psychosis

Frontiers in Human Neuroscience, 2013
Objective: Neurocognitive impairment is commonly reported at onset of psychotic disorders. However, the long-term neurocognitive course remains largely uninvestigated in first episode psychosis (FEP) and the relationship to clinically significant ...
Helene Eidsmo Barder, Helene Eidsmo Barder, Helene Eidsmo Barder, Kjetil eSundet, Kjetil eSundet, Bjørn eRund, Bjørn eRund, Julie eEvensen, Julie eEvensen, Ulrik eHaahr, Wenche eHegelstad, Inge eJoa, Jan Olav eJohannessen, Jan Olav eJohannessen, Johannes eLangeveld, Tor Ketil eLarsen, Tor Ketil eLarsen, Ingrid eMelle, Ingrid eMelle, Stein eOpjordsmoen, Stein eOpjordsmoen, Jan Ivar eRøssberg, Jan Ivar eRøssberg, Erik eSimonsen, Per eVaglum, Thomas eMcGlashan, Svein eFriis, Svein eFriis   +27 more
doaj   +1 more source

CausalCellInfer: Prioritizing Cell‐Type‐Specific Disease Associations From Genetically Predicted Transcriptomes in Biobank Cohorts

Advanced Science, EarlyView.
Bulk and genotype‐imputed transcriptomes obscure the cellular drivers of complex disease. CausalCellInfer resolves them by integrating invariant marker selection, deep learning deconvolution, and regularized matrix completion. Applied to ∼500 000 UK Biobank participants across 29 traits, it uncovers hallmark cell‐type proportion shifts, including ...
Liangying Yin, Yujia Shi, Ruoyu Zhang, Yong Xiang, Jinghong Qiu, Pak‐Chung Sham, Hon‐Cheong So   +6 more
wiley   +1 more source

A cognitive model of the positive symptoms of psychosis [PDF]

, 2001
In the last 10 years a consensus has developed that the symptoms of psychosis may be better understood by linking the steps between the phenomenological experiences and social, psychological and neurobiological levels of explanation.
Garety, PA, Freeman, D, Fowler, D, Kuipers, E, Freeman, D., Bebbington, PE, Bebbington, P. E., Fowler, D. G., Bebbington, P, Garety, P; id_orcid, Garety, P. A., Kuipers, E; id_orcid, Kuipers, E., D. FOWLER, P. A. GARETY, Freeman, Daniel, E. KUIPERS, D. FREEMAN, P. E. BEBBINGTON   +18 more
core   +1 more source

Successful clozapine re-challenge in a patient with three previous episodes of clozapine-associated blood dyscrasia

BJPsych Open, 2017
A case is presented of a 30-year-old female with treatment-resistant schizoaffective disorder who was referred to a tertiary-level specialist psychosis service.
Jessica Foster, John Lally, Victoria Bell, Sukhi Shergill   +3 more
doaj   +1 more source

B/ordering and healthcare access for migrants with precarious status: The role of healthcare workers in counteracting restrictive policies

American Journal of Community Psychology, EarlyView.
Abstract In Canada, precarious migration is largely invisibilized. Nonetheless, b/ordering greatly affects people's realities by limiting access to social rights. In Quebec, migrants with precarious status (MPS) do not have access to healthcare, although Quebec has a “universal” healthcare coverage.
Émilie Pigeon‐Gagné, Jill Hanley, Élise Bourgeois‐Guérin, Pénélope Boudreault   +3 more
wiley   +1 more source

Transitioning to nonpunitive school policies for addressing student substance use: Qualitative interviews with key school administrators

American Journal of Community Psychology, EarlyView.
Abstract Recent policy change in Massachusetts encourages schools to limit their use of exclusionary discipline to “extraordinary circumstances,” but little work has explored the opportunities and challenges of transitioning to nonpunitive practices after student substance use infractions in schools.
Kristina Conroy, M. Grace Albright, Kendall B. Roberts, Meghan A. Costello, Anthony J. Jannetti, Alexis R. Wing, Randi M. Schuster   +6 more
wiley   +1 more source