Results 111 to 120 of about 24,901 (225)
Abstract Background and aims There are currently no brief quantitative assessments that capture the drug patterns of people who engage in use of more than one drug on the same day or simultaneously. The current study examined the retest reliability, acceptability and feasibility of a new quantitative assessment to measure polysubstance use.
Amanda M. Bunting +7 more
wiley +1 more source
The neurobiology of psychostimulant addiction [PDF]
Introducción y desarrollo. Las drogas psicoestimulantes incluyen anfetamínicos, alcaloides naturales como la cocaína y metilxantinas. Inducen una fuerte dependencia, que se manifiesta por fenómenos de base neurobiológica como la sensibilización y la ...
Fernández-Espejo, Emilio
core
ABSTRACT Background Although semaglutide 2.4 mg has demonstrated significant weight loss efficacy in clinical trials, real‐world data, particularly with regard to clinically complex and underrepresented populations, remain limited. Objectives The study aims to assess the real‐world effectiveness and patient‐reported outcomes associated with the use of ...
Pierre Bel Lassen +20 more
wiley +1 more source
Psychostimulant Drugs and Neuroplasticity
Drugs of abuse induce plastic changes in the brain that seem to underlie addictive phenomena. These plastic changes can be structural (morphological) or synaptic (biochemical), and most of them take place in the mesolimbic and mesostriatal circuits ...
Emilio Fernandez-Espejo +1 more
doaj +1 more source
Genome‐wide association analyses in outbred Sprague–Dawleys identified loci for anxiety‐like and nociceptive behavior on chromosomes 1, 14, and 17, which are distinct from facets of exploratory locomotion significant in our GWAS of a F2 intercross of selectively bred high‐ and low‐responder (to a novel environment) Sprague–Dawleys.
Apurva S. Chitre +11 more
wiley +1 more source
Addiction to psychostimulants like cocaine, methamphetamine, and nicotine poses a continuing medical and social challenge both in the United States and all over the world. Despite a desire to quit drug use, return to drug use after a period of abstinence
Manoranjan S. D’Souza
doaj +1 more source
Rationale for psychostimulants in ADHD [PDF]
EDITOR—Confusion about levels of diagnosis causes most debate about psychostimulants in childhood behavioural disorders.1 DSM-IV definitions are all syndromes—that is, symptoms and signs unrelated to pathology and aetiology. Most effective therapies treat pathology and aetiology; syndromes can be treated only symptomatically.
openaire +2 more sources
In a sample of 13 early‐abstinent methamphetamine users (≤30 days) and 14 controls, multimodal MRI revealed lower cortical volume in frontal and lingual regions and thickness of the lateral occipital and lingual cortex. These structural changes accompanied poorer executive performance, suggesting dose‐related grey‐matter vulnerability in visual ...
Ben Bristow +13 more
wiley +1 more source
Stable interindividual differences in modafinil’s effect on vigilance during sleep deprivation
RationaleIn specific operational contexts (i.e., military aviation), the off-label use of modafinil is officially regulated. However, safety concerns are still raised.ObjectivesTo study the stability and robustness of interindividual differences in ...
Jeroen Van Cutsem +24 more
doaj +1 more source
Currently, there are no approved pharmacotherapies for addiction to cocaine and other psychostimulant drugs. Several studies have proposed that cannabidiol (CBD) could be a promising treatment for substance use disorders. In the present work, the authors
Claudia Calpe-López +2 more
doaj +1 more source

