Results 101 to 110 of about 24,901 (225)

Differential Behavioral Responses to\ud Cocaethylene of Long-Evans and\ud Sprague-Dawley Rats: Role of Serotonin [PDF]

, 1997
Cocaethylene is a neuroactive metabolite derived from the concurrent consumption of cocaine and ethanol. The effects of cocaethylene on locomotor activity, stereotypy, and rearing in Long-Evans and Sprague-Dawley rats were compared.A single cocaine ...
Horowitz, Dr. J.M., Kristal, Dr. M.B., Torres, Dr. G.   +2 more
core  

Ghrelin receptor antagonism attenuates cocaine- and amphetamine-induced locomotor stimulation, accumbal dopamine release, and conditioned place preference [PDF]

, 2010
INTRODUCTION: Recently we demonstrated that genetic or pharmacological suppression of the central ghrelin signaling system, involving the growth hormone secretagogue receptor 1A (GHS-R1A), lead to a reduced reward profile from alcohol.
Elisabet Jerlhag, Emil Egecioglu, Suzanne L. Dickson, Jörgen A. Engel, A Abizaid, G Addolorato, SM Bell, O Blomqvist, KD Carr, ME Carroll, ME Carroll, KW Davis, SL Dickson, JA Engel, JA Engel, KBJ Franklin, O Gualillo, AK Hewson, T Hillemacher, B Holst, A Imperato, E Jerlhag, E Jerlhag, E Jerlhag, E Jerlhag, E Jerlhag, H Jiang, E Keen-Rhinehart, DJ Kim, FH Kobeissy, M Kojima, T Kraus, S Landgren, S Malik, A Moulin, R Nogueiras, ME Reith, N Salomé, HH Samson, C Sanchis-Segura, ER Schneider, M Tessari, PJ Wellman, BHC Westerink, FJ White, RA Wise, XF Zhang   +46 more
core   +1 more source

Innovative Nanomaterial‐Based Approaches for the Recognition of Amphetamine in Attention Deficit Hyperactivity Disorder Management

Analytical Science Advances, Volume 7, Issue 1, June 2026.
ABSTRACT The rising incidence of amphetamine misuse, particularly in the context of attention deficit hyperactivity disorder treatment, underscores the urgent need for sensitive and effective detection methods. This review examines innovative nanomaterial‐based approaches for AMP detection, emphasizing their advantages over conventional analytical ...
Ilghar Zeinaly, Ghazal Koohkansaadi, Majid Hassanzadeh‐Khanmiri, Ahmad Mobed, Saeid Charsouei, Arash Mohagheghi   +5 more
wiley   +1 more source

Psychostimulant-related health service demand in an inner-city hospital, 2012–2015

Public Health Research & Practice, 2018
Objective: To analyse routinely collected data from a hospital database of drug health consultation-liaison (CL) assessments. We aimed to investigate changes in psychostimulant-related health service demand in an inner-city hospital to inform the ...
Alon Faingold, Kirsten Morley, Bethany White, Emily Walker, Paul Haber   +4 more
doaj   +1 more source

Captagon: Use and Trade in the Middle East [PDF]

, 2016
This is the peer-reviewed version of the following article: ‘Captagon: Use and Trade in the Middle East’, which has been published in final form at http://onlinelibrary.wiley.com/doi/10.1002/hup.2548/abstract . This article may be used for non-commercial
Al-hemiary, Al-Hussaini, Alabdalla, Arslan, Barnes, Bigdeli, Chen, Chen, Chen, Chen, Corazza, Corazza, Defalque, Ellison, Gabriel, Herbert, Katselou, Kikura, Kristen, Liginlal, Liginlal, Nichols, Sattari, Shahrour, Shufman, Ulucay, Van Hout, Young   +27 more
core   +2 more sources

A New Kinetic‐Mechanistic Approach Towards Spectrophotometric Bioanalysis of 2‐Phenylethylamine as a Sympathomimetic Agent Using Sodium Isopropyl Xanthate

Analytical Science Advances, Volume 7, Issue 1, June 2026.
ABSTRACT 2‐Phenylethylamine (2‐PEA), an aromatic biogenic amine, demonstrates significant physiological and toxicological effects on human health. A variety of conventional methods have been widely used for the determination of 2‐PEA. However, the necessity of complex sample preparation and high cost of instrumentation may pose challenges to their ...
Fatemeh Nami, Houman Kholafazad, Mohammad Hasanzadeh, Nasrin Shadjou   +3 more
wiley   +1 more source

Pharmacological profiles of aminoindanes, piperazines, and pipradrol derivatives [PDF]

, 2014
Aminoindanes, piperazines, and pipradrol derivatives are novel psychoactive substances found in "Ecstasy" tablets as replacements for 3,4-methylenedioxymethamphetamine (MDMA) or substances sold as "ivory wave." The pharmacology of these MDMA- and ...
Hoener, Marius C., Liechti, Matthias E., Rickli, Anna, Schramm, York, Simmler, Linda D.   +4 more
core   +1 more source

Adolescent Exposure to Nicotine and Ethanol Attenuates Adult Nicotine Reward Sensitivity in Rats

Neuropsychopharmacology Reports, Volume 46, Issue 2, June 2026.
We investigated how chronic exposure to nicotine, ethanol, or their combination during adolescence influences adult conditioned place preference (CPP) for nicotine. No significant CPP was observed in any of the drug‐exposed groups, suggesting adolescent exposure to addictive substances does not uniformly increase vulnerability to nicotine reward ...
Michimasa Toyoshima, Ryota Toyofuku, Shota Shimoda, Lena Tsuchida, Reina Tachihara, Kazuo Yamada   +5 more
wiley   +1 more source

Cdk5 Phosphorylates Dopamine D2 Receptor and Attenuates Downstream Signaling [PDF]

The dopamine D2 receptor (DRD2) is a key receptor that mediates dopamine-associated brain functions such as mood, reward, and emotion. Cyclin-dependent kinase 5 (Cdk5) is a proline-directed serine/threonine kinase whose function has been implicated in ...
Gho, YS, Hwang, D, Jeong, J, Kim, DK, Kwak, Y, Lee, H, Lee, S, Lee, SA, PARK, SANG KI, Park, YU, Suh, YH   +10 more
core   +1 more source

Caffeine. cognitive and physical performance enhancer or psychoactive drug? [PDF]

, 2015
Caffeine use is increasing worldwide. The underlying motivations are mainly concentration and memory enhancement and physical performance improvement. Coffee and caffeine-containing products affect the cardiovascular system, with their positive inotropic
Aromatario, Mariarosaria, Cappelletti, Simone, Piacentino, Daria, Sani, Gabriele   +3 more
core   +1 more source