Results 81 to 90 of about 24,901 (225)

5‐HT2A receptor agonism by tert‐leucinamide and valinamide synthetic cannabinoids: In vitro and in vivo evidence

British Journal of Pharmacology, EarlyView.
Abstract Background and Purpose New synthetic cannabinoid receptor agonists (SCRAs) are associated with severe adverse effects, including unexpected psychiatric symptoms. These compounds are mainly active through their potent agonism on the cannabinoid receptors CB1 and CB2.
Giorgia Corli, Deborah Rudin, Dino Luethi, Matthias E. Liechti, Sabrine Bilel, Matteo Marti, Henrik Green, Manuela Carla Monti, Caitlyn Norman   +8 more
wiley   +1 more source

Context-dependent effects of a single administration of mirtazapine on the expression of methamphetamine-induced conditioned place preference

Frontiers in Behavioral Neuroscience, 2012
Re-exposure to cues repeatedly associated with methamphetamine (Meth) can trigger Meth-seeking and relapse in the abstinent abuser. Weakening the conditioned Meth-associated memory during cue re-exposure may provide a means for relapse-reduction ...
Robin eVoigt, T. Celeste eNapier
doaj   +1 more source

Present and future trajectories towards a possible valid and useful diagnosis of ADHD [PDF]

, 2016
To date, diagnosing Attention Defi cit Hyperactivity Disorder remains indeed one of the most controversial issues in contemporary psychiatry and behavioural sciences.
De Rossi, Piero
core  

Mechanisms Regulating the Association of Protein Phosphatase 1 with Spinophilin and Neurabin [PDF]

, 2018
Protein phosphorylation is a key mediator of signal transduction, allowing for dynamic regulation of substrate activity. Whereas protein kinases obtain substrate specificity by targeting specific amino acid sequences, serine/threonine phosphatase ...
Baucum, Anthony J., II, Edler, Michael C., Kaur, Harjot, Morris, Cameron W., Salek, Asma B., Watkins, Darryl S., Yamamoto, Bryan K.   +6 more
core   +1 more source

TAAR1 and Psychostimulant Addiction

Cellular and Molecular Neurobiology, 2020
Trace amine-associated receptor 1 is one of the best-characterized receptors of trace amines. Growing evidence shows that TAAR1 negatively regulates the monoaminergic activity, including dopamine transmission in the mesocorticolimbic system. Neurochemical assays demonstrated that selective TAAR1 full and partial agonists were effective to prevent ...
Jianfeng, Liu, Ruyan, Wu, Jun-Xu, Li
openaire   +3 more sources

Understanding Empathy in Patient‐Centered Dentistry: The Role of Emotional Intelligence and Psychosocial Factors

European Journal of Dental Education, EarlyView.
ABSTRACT Objective This study investigated the relationship between empathy and emotional intelligence (EI) among undergraduate dental students and explored the effects of demographic and psychosocial factors on empathy levels. Methods A cross‐sectional survey was conducted among first‐ to fifth‐year dental students between May and June 2025. Data were
Sevgi Güngör, Leyla Kerimova‐Köse, Ruhsan Müdüroğlu‐Adıgüzel, Neslihan Arhun   +3 more
wiley   +1 more source

Psychostimulants and Movement Disorders [PDF]

Frontiers in Neurology, 2015
Psychostimulants are a diverse group of substances with their main psychomotor effects resembling those of amphetamine, methamphetamine, cocaine, or cathinone. Due to their potential as drugs of abuse, recreational use of most of these substances is illegal since 1971 Convention on Psychotropic Substances.
Asser, Andres, Taba, Pille
openaire   +3 more sources

Conventional cigarettes, novel heated tobacco products, and self‐reported frequent headache association in Japanese individuals: Insights from the JASTIS study, a Japanese cross‐sectional analysis

Headache: The Journal of Head and Face Pain, EarlyView.
Plain Language Summary Headache is a common health problem, and tobacco products, such as conventional cigarettes and heated tobacco products (HTPs), may be associated with it. Using data from over 23,000 adults in the Japan Society and New Tobacco Internet Survey, we examined the relationships between cigarette and HTP use and self‐reported frequent ...
Masahito Katsuki, Kieran Moran, Muneto Tatsumoto, Keisuke Suzuki, Tomokazu Shimazu, Yasuhiko Matsumori, Yutaro Fuse, Miguel Á. Huerta, Daijiro Sugiyama, Jackson T. S. Cheung, Siobhán O'Connor, Tomás Ward, Takahiro Tabuchi   +12 more
wiley   +1 more source

Effects of psychostimulant withdrawal on latent inhibition of conditioned active avoidance and prepulse inhibition of the acoustic startle response [PDF]

, 2018
.: Rationale: Chronic intermittent administration of amphetamine and cocaine can precipitate psychotic episodes in humans and produce persistent behavioral changes (i.e. increased locomotion, stereotypy) in the rat.
Di Iorio, Lucia, Feldon, Joram, Murphy, Carol   +2 more
core  

Class I HDAC Inhibition Blocks Cocaine-Induced Plasticity Through Targeted Changes in Histone Methylation [PDF]

, 2014
Induction of histone acetylation in the nucleus accumbens (NAc), a key brain reward region, promotes cocaine-induced alterations in gene expression. Histone deacetylases (HDACs) tightly regulate the acetylation of histone tails, but little is known about
Badimon, Ana, Bassel-Duby, Rhonda, Chaudhury, Dipesh, Damez-Werno, Diane M., Feng, Jian, Haggarty, Stephen J., Han, Ming-Hu, Kennedy, Pamela J., Maze, Ian, Mouzon, Ezekiell, Nestler, Eric J., Olson, Eric N., Robison, A.J.   +12 more
core   +1 more source