Results 41 to 50 of about 24,654 (226)
Neurologic Clinics, 1993 Psychomotor stimulants possess intrinsic reinforcing properties that may lead to dependence and abuse. Epidemics of stimulant abuse have occurred historically in cycles related to introduction of new stimulants or new routes of administration. The actions and toxic effects of stimulants are related primarily to interaction with the central and ...
openaire +2 more sources
Treatment of ADHD in a patient with Brugada syndrome: a case report and a brief review
Psychiatry and Clinical Psychopharmacology, 2018 The Brugada syndrome is one of the common causes of sudden cardiac arrest in healthy-appearing adults. The use of drugs in the treatment of this disease may give variable and unwanted results.
Pınar Demir Gündoğmuş +5 more
doaj +1 more source
From clinical application to cognitive enhancement: the example of methylphenidate [PDF]
, 2016 Methylphenidate (MPD) is a central nervous system (CNS) stimulant, which belongs to the phenethylamine group and is mainly used in the treatment of attention deficit hyperactive disorder (ADHD).
Busardo', FRANCESCO PAOLO +4 more
core +1 more source
CellsAttention-deficit/hyperactivity disorder (ADHD) is a neurodevelopmental condition marked by persistent inattention, hyperactivity, and impulsivity. Despite its considerable global prevalence, key gaps remain in our understanding of the structural and ...
Matthew William Yacoub +7 more
doaj +1 more source
The role of setting for ketamine abuse: clinical and preclinical evidence [PDF]
, 2012 Drug abuse is often seen as a unitary phenomenon, partly as a result of the discovery over the past three decades of shared mechanisms of action for addictive substances. Yet the pattern of drug taking is often very different from drug to drug.
Sprenger +8 more
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Carvedilol inhibits the cardiostimulant and thermogenic effects of MDMA in humans : lost in translation [PDF]
, 2013 We greatly appreciate the comments offered by Drs Rolle, Takematsu, and Hoffman and the opportunity to put our work into a wider perspective. We share the view that our work does not reflect the clinical situation but rather provides a proof of mechanism
Boehrer +26 more
core +1 more source
The Use of Central Nervous System Active Drugs During Pregnancy
Pharmaceuticals, 2013 CNS-active drugs are used relatively often during pregnancy. Use during early pregnancy may increase the risk of a congenital malformation; use during the later part of pregnancy may be associated with preterm birth, intrauterine growth disturbances and ...
Bengt Källén +2 more
doaj +1 more source
Epilepsia, EarlyView.Abstract Objective Sigma‐1 is a chaperone protein that serves as a key homeostatic regulator, implicated in neuronal excitability and seizure control. Positive allosteric modulators offer a use‐dependent means to enhance Sigma‐1 activity, potentially with favorable tolerability compared to direct agonists.
Eva‐Lotta von Rüden +5 more
wiley +1 more source
Risk Factors of Suicidal Ideation in Iraqi Crystal Methamphetamine Users
Brain Sciences, 2023 Crystal methamphetamine, a potent psychostimulant, presents a complex clinical landscape. However, insights into the predisposing factors for suicidal tendencies among Iraqi users remain limited.
Ahmed Al-Imam +6 more
doaj +1 more source