Results 51 to 60 of about 24,654 (226)

Behavioral Phenotyping of Dopamine Transporter Knockout Rats: Compulsive Traits, Motor Stereotypies, and Anhedonia [PDF]

, 2018
Alterations in dopamine neurotransmission are generally associated with diseases such as attention-deficit/hyperactivity disorder (ADHD) and obsessive-compulsive disorder (OCD).
Anna Poleggi, Damiana Leo, Enrico Alleva, Francesca Zoratto, Giovanni Laviola, Luca Cerniglia, Raul R. Gainetdinov, Raul R. Gainetdinov, Renata Tambelli, Silvia Cimino, Stefano Cinque, Stefano Cinque, Walter Adriani, Walter Adriani   +13 more
core   +2 more sources

Dietary and biomarker‐guided strategies as supportive measures in the fragile X syndrome

Food Biomacromolecules, EarlyView.
Abstract The fragile X syndrome (FXS) is an inherited neurodevelopmental disorder that primarily affects males, often resulting in an IQ below 55, while about two‐thirds of females also experience intellectual disability. Physical features may include an elongated face, prominent ears, finger joint laxity, and enlarged testes in males.
Jailan E. El Halawani, Reem R. AlOlaby
wiley   +1 more source

Effectiveness of Psychostimulant and Non-Psychostimulant Drug Therapy in the Attention Deficit Hyperactivity Disorder

Applied Sciences, 2021
Attention Deficit Hyperkinetic Disorder (ADHD) is a neurobiological behavioral disorder of the child, adolescent, and adult characterized by problems of concentration, hyperactivity, and impulsivity caused by an imbalance of chemical neurotransmitters in
Adriana Cojocaru, Lavinia Maria Hogea, Vladimir Poroch, Mihaela Adriana Simu, Virgil Radu Enatescu, Roxana Jeleriu, Nicoleta Ioana Andreescu, Maria Puiu, Bogdan Gheorghe Hogea, Mirela Grigoras, Roxana Folescu, Carmen Lăcrămioara Zamfir, Ileana Enatescu, Laura Alexandra Nussbaum   +13 more
doaj   +1 more source

Psychiatric Comorbidity, Tic Severity and Quality of Life in Adults with Tourette's Syndrome

Movement Disorders Clinical Practice, EarlyView.
Abstract Background Psychiatric comorbidities are common in adults with Tourette's Syndrome (TS), and appear to influence both tic severity and quality of life (QOL). Objective To assess the association between psychiatric comorbidities, tic severity and QOL in TS.
Andreas Hartmann, Christelle Nilles, Yulia Worbe, Davide Martino, Naoual Serari, Catherine Deans, Isabella Davenport, Julian Fletcher, Emmanuel Roze, Tamara Pringsheim   +9 more
wiley   +1 more source

Acute Pharmacological Effects of Oral and Intranasal Mephedrone: An Observational Study in Humans

Pharmaceuticals, 2021
Mephedrone (4-methylmethcathinone) is a synthetic cathinone with psychostimulant properties which remains one of the most popular new psychoactive substances (NPS). It is frequently used orally and/or intranasally.
Esther Papaseit, Eulalia Olesti, Clara Pérez-Mañá, Marta Torrens, Francina Fonseca, Marc Grifell, Mireia Ventura, Rafael de la Torre, Magí Farré   +8 more
doaj   +1 more source

Distinct Brain Drivers and Shared Cerebello–Cortical Input in ADCY5 and SGCE Hyperkinetic Movements

Movement Disorders, EarlyView.
Resting‐state fMRI and effective connectivity revealed distinct cerebellar–basal ganglia–cortical interactions in ADCY5 (MxMD‐ADCY5) and SGCE (MYC/DYT‐SGCE) related movement disorders. The cerebellum modulated cortex directly in MYC/DYT‐SGCE, but indirectly via basal ganglia‐cerebellar projections in MxMD‐ADCY5, which also showed reduced subthalamic ...
Clément Tarrano, Cécile Galléa, Asya Ekmen, Cécile Delorme, Eavan M. McGovern, Quentin Salardaine, Lina Daghsen, Manon Gomes, Vanessa Brochard, Eoin Mulroy, Kailash P. Bhatia, Carlo Fusco, Miryam Carecchio, Norbert Brüggemann, Alexander Münchau, Victoria Gonzalez, Diane Doummar, Christine Tranchant, Mathieu Anheim, Philippe Damier, Florence Riant, Mohamed Doulazmi, Agathe Roubertie, Caroline Dubacq, Oriane Trouillard, Romain Valabregue, Mélanie Didier, Benoit Beranger, Pierre Pouget, Marie Vidailhet, Sabine Meunier, Aurélie Méneret, Yulia Worbe, Emmanuel Roze   +33 more
wiley   +1 more source

Efficacy and tolerability of psychostimulants for symptoms of attention-deficit hyperactivity disorder in preschool children: A systematic review and meta-analysis

European Psychiatry, 2023
Background There was no previous meta-analysis investigating the efficacy/tolerability of psychostimulants for symptoms of attention-deficit hyperactivity disorder (ADHD) in preschool children.
Hsien-Jane Chiu, Cheuk-Kwan Sun, Yu-Shian Cheng, Ming Yu Wang, Ruu-Fen Tzang, Feng-Li Lin, Ying-Chih Cheng, Weilun Chung   +7 more
doaj   +1 more source

Clinical Predictors of Tic‐Related Impairment in Children and Adults with Tourette Syndrome

Movement Disorders, EarlyView.
Abstract Background Tic‐related impairment drives treatment decisions for Tourette syndrome and related tic disorders. The clinical features most strongly associated with impairment remain unclear. Objective The aim of this analysis is to identify clinical predictors of tic‐related impairment in children and adults with tic disorders in a prospective ...
Wm. Jeptha Davenport, Davide Martino, Christos Ganos, Christelle Nilles, Tamara Pringsheim   +4 more
wiley   +1 more source

Differential effects of MDMA and methylphenidate on social cognition [PDF]

, 2014
Social cognition is important in everyday-life social interactions. The social cognitive effects of 3,4-methylenedioxymethamphetamine (MDMA, 'ecstasy') and methylphenidate (both used for neuroenhancement and as party drugs) are largely unknown.
Crockett, Molly J., Hysek, Cédric M., Liechti, Matthias E., Quednow, Boris B., Schmid, Yasmin, Simmler, Linda D.   +5 more
core   +1 more source

Stem cell–mediated neuroplasticity and psychological recovery in cancer survivors: Mechanisms, evidence, and translational challenges

Precision Medical Sciences, EarlyView.
Cancer therapies can trigger neuroinflammation and disrupted neuroplasticity, contributing to cognitive impairment and psychological distress in survivors. Stem cells (NSCs/MSCs) and their extracellular vesicles may restore neural niches via trophic support, immunomodulation, synaptic remodeling, and vascular repair, but require rigorous safety, dosing,
Xinyi Yang
wiley   +1 more source