Results 51 to 60 of about 109,672 (264)

Gestational Hypoxia Disrupts Medial Ganglionic Eminence Progenitor Dynamics and Interneuron Development in Schizophrenia

Advanced Science, EarlyView.
FES‐derived MGE spheroids exhibit progenitor‐stage alterations in developmental trajectory and hypoxia‐responsive transcriptional programs, followed by functional disruption. Gestational hypoxia recapitulates impaired progenitor proliferation, shortened cell‐cycle progression, interneuron developmental abnormalities, and schizophrenia‐like behaviors in
Peiyan Ni, Qiancheng Zhang, Youhui Jiang, Huiying Yao, Chuqing Zhou, Xiaoyi Tian, Shiyingnan Gao, Jun Zhao, Xinyi Ren, Naxin Xu, Mengshan Fu, Liansheng Zhao, Xueyu Qi, Xueli Yu, Wanjun Guo, Sangmi Chung, Fan Guo, Tao Li   +17 more
wiley   +1 more source

Mediational effect analysis of childhood emotional abuse on prodromal psychotic symptoms in self-taught examination students

Scientific Reports
It has been shown that childhood trauma is associated with an increased risk of prodromal psychotic symptoms. However, research on the prevalence of prodromal psychotic symptoms among self-taught examination students and the relationship with childhood ...
Yanchi Wang, Dandan Wu, Jinjun Wang, Yuan Chen, Xiang Chen, Wen Shi, Qing Xia, Jian Gu   +7 more
doaj   +1 more source

Psychotic symptoms in acromegaly

Indian Journal of Psychiatry, 2005
Various psychiatric symptoms have been reported in patients with acromegaly. Most of them are personality changes characterized by lack of initiative and spontaneity. There are few case reports of the presence of auditory and visual hallucinations, and delusions in patients with acromegaly. We report a patient with acromegaly who had psychotic symptoms
Pinto, Denzil, Safeekh, A.T., Trivedi, Mohit   +2 more
openaire   +2 more sources

Diagnosing the system: Mental health, necropolitical uncare, and the abolition of migration detention

American Journal of Community Psychology, EarlyView.
Abstract This article examines the psychological effects of migration detention in the European Union's Closed Controlled Access Center (CCAC) on Samos through an ecological lens. It explores a double normalization of suffering: the brutalization of necropolitical migration governance and the simultaneous understanding of resulting distress as an ...
Julia Manek
wiley   +1 more source

Moral cognition, the missing link between psychotic symptoms and acts of violence: a cross-sectional national forensic cohort study

BMC Psychiatry, 2019
Background People with schizophrenia are ten times more likely to commit homicide than a member of the general population. The relationship between symptoms of schizophrenia and acts of violence is unclear.
Ken O’Reilly, Paul O’Connell, Danny O’Sullivan, Aiden Corvin, James Sheerin, Padraic O’Flynn, Gary Donohoe, Hazel McCarthy, Daniela Ambrosh, Muireann O’Donnell, Aisling Ryan, Harry G. Kennedy   +11 more
doaj   +1 more source

Distinct Neuropsychiatric Profiles Associated With 17p11.2 Deletions and RAI1 Variants in Smith–Magenis Syndrome

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Smith–Magenis syndrome (SMS) results from either a recurrent 17p11.2 deletion or pathogenic variants in the retinoic acid induced 1 gene (RAI1). While neurodevelopmental impairment and behavioral dysregulation are well recognized, systematic genotype‐stratified analyses across psychiatric domains remain limited.
Albin Blanc, Christophe Nemos, Céline Bonnet, Mathilde Renaud, Sandra Chapuis, Pauline Boiroux, Marie‐Noëlle Babinet, Caroline Demily   +7 more
wiley   +1 more source

An Adult Presentation of KIF11‐Related MCLID Syndrome: Case Report and 40‐Year Follow‐Up

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Pathogenic variants in KIF11 are linked to autosomal dominant syndromes with microcephaly, chorioretinopathy, lymphedema, and intellectual disability (MCLID), though adult presentations remain underreported. We report a 42‐year‐old female presenting with a de novo single‐amino acid in‐frame deletion in the KIF11 gene (c.1294_1296del; p ...
Thrishna Chathurvedula, Juvy Rabelas, Kareem Touleimat, Elaine Marchi, Ruhi Shah, Shaydah Kheradmand, Kuldeep Singh, Karen Amble, Gholson J. Lyon   +8 more
wiley   +1 more source

Abnormal prefrontal brain activation during a verbal fluency task in bipolar disorder patients with psychotic symptoms using multichannel NIRS

Neuropsychiatric Disease and Treatment, 2018
Jing-Jing Sun,1,2 Xiao-Min Liu,2 Chen-Yu Shen,2 Kun Feng,1,2 Po-Zi Liu2 1School of Clinical Medicine, Medicine Institute, Tsinghua University, Beijing, China; 2Yu Quan Hospital, Clinical Neuroscience Institute, Tsinghua University, Beijing, China ...
Sun JJ, Liu XM, Shen CY, Feng K, Liu PZ
doaj  

Reporting a Case of Injecting Methylphenidate (Ritalin) Tablets, Intensified Symptoms of Schizoph-renia or Induce Separate Mental Disorder [PDF]

Addiction and Health, 2010
Background: Methylphenidate is one of the classic amphetamines which can cause or exacerbate psychotic symptoms in schizophrenia patients. Methods: In this paper, a young man is presented with injection of methylphenidate tablets with acute ...
Alireza Ghaffarinejad, Ali Kheradmand
doaj  

Khat use as risk factor for psychotic disorders: A cross-sectional and case-control study in Somalia

BMC Medicine, 2005
Background Little is known about the prevalence of khat-induced psychotic disorders in East African countries, where the chewing of khat leaves is common. Its main psycho-active component cathinone produces effects similar to those of amphetamine.
Elbert Thomas, Schauer Maggie, Neuner Frank, Odenwald Michael, Catani Claudia, Lingenfelder Birke, Hinkel Harald, Häfner Heinz, Rockstroh Brigitte   +8 more
doaj   +1 more source