Results 121 to 130 of about 107,636 (348)

Carrier-free nanomedicines: Mechanisms of formation and biomedical applications

Giant
In recent years, significant advancements in nanotechnology have yielded remarkable improvements in biomedical applications. Nanocarriers, harnessed from the principles of nanotechnology, have garnered widespread utilization in medicine delivery and ...
Xinrui Dong, Hu Liu, Haibao Liu, Xiaoqin Zhang, Xiaoran Deng   +4 more
doaj   +1 more source

Psychotropic drug use and mortality in old people with dementia: investigating sex differences [PDF]

, 2017
Jon Brännström, Gustaf Boström, Erik Rosendahl, Peter Nordström, Håkan Littbrand, Hugo Lövheim, Yngve Gustafson   +6 more
openalex   +1 more source

Analytical Approaches to Address Challenges in the Analysis of Cannabinoids in Vascular Matrices Using Mass Spectrometry

Mass Spectrometry Reviews, EarlyView.
ABSTRACT Phytocannabinoids are bioactive metabolites derived from the Cannabis sativa plant. They have garnered attention due to their recreational uses and therapeutic potential. Although various analytical strategies have been employed for their analysis, mass spectrometry (MS) coupled to chromatographic separation is superior due to its sensitivity ...
Radwa Mahmoud, Robert B. Laprairie, Anas El‐Aneed   +2 more
wiley   +1 more source

Opium trade and use during the Late Bronze Age: Organic residue analysis of ceramic vessels from the burials of Tel Yehud, Israel

Archaeometry, EarlyView., 2022
Abstract Organic residue analysis was conducted on various vessels from burials at Tel Yehud, Israel. The analyses led to new reliable evidence for the presence of opioid alkaloids and their decomposition products. This research revitalizes a decades‐old discussion on the presence and function of the opium trade across a cultural region of utmost ...
Vanessa Linares, Eriola Jakoel, Ron Be’eri, Oded Lipschits, Ronny Neumann, Yuval Gadot   +5 more
wiley   +1 more source

The microglial innate immune receptor TREM2 participates in fear memory formation through excessive prelimbic cortical synaptic pruning

Frontiers in Immunology
IntroductionFear memory formation has been implicated in fear- and stress-related psychiatric disorders, including post-traumatic stress disorder (PTSD) and phobias.
Le-le Zhang, Le-le Zhang, Le-le Zhang, Peng Cheng, Peng Cheng, Peng Cheng, Yuan-qing Chu, Yuan-qing Chu, Yuan-qing Chu, Zi-ming Zhou, Zi-ming Zhou, Zi-ming Zhou, Rong Hua, Yong-mei Zhang, Yong-mei Zhang, Yong-mei Zhang   +15 more
doaj   +1 more source

Your Drug May Be Your Problem: How and Why to Stop Taking Psychotropic Medications [PDF]

, 2000
William A. Kehoe
openalex   +1 more source

The risk of a blood pressure increase during treatment with selected psychotropic drugs

, 2022
Monika Romańczyk, Stanisław Surma, Beata Kocyan, Karolina Kłos, Wiktoria Strona, Marek Krzystanek   +5 more
openalex   +2 more sources

Underlying Mechanisms of the Treatment Efficacy of (R, S)‐Ketamine for Post‐Traumatic Stress Disorder and Depression: A Review

Medicine Advances, EarlyView.
Research shows that (R, S)‐ketamine and its stereoisomers effectively reduce symptoms of post‐traumatic stress disorder (PTSD) and treatment‐resistant depression, with (R)‐ketamine offering similar benefits with fewer side effects. Evidence highlights specific neural circuits and regions, including the dentate gyrus, prefrontal cortex, vCA3, dorsal ...
Thomas Edward Cutting, Richard Evans Hartman   +1 more
wiley   +1 more source

The ketogenic diet alters microbiome‐metabolome profiles to improve West syndrome therapy

Pediatric Investigation, EarlyView.
The ketogenic diet alleviates West syndrome by reshaping gut microbiota (increasing Bacteroides, Parabacteroides, and reducing Escherichia and Bifidobacterium), and modulating metabolites—including anticonvulsant lipids (e.g., capric acid), suppressed harmful lipids (e.g., 2‐methylbutyroylcarnitine), and amino acids and analogs (e.g., 3‐sulfinoalanine)—
Gan Xie, Qian Zhou, Jianxiang Liao, Yuejie Zheng, Wenjian Wang, Kunling Shen   +5 more
wiley   +1 more source

Effect of transcutaneous auricular vagus nerve stimulation on postoperative liver function in patients undergoing partial hepatectomy: a study protocol for a prospective, double-blind, randomized controlled trial

Frontiers in Medicine
BackgroundPartial hepatectomy remains a primary therapeutic intervention for various hepatic diseases. However, several intraoperative factors, including surgical manipulation, substantial blood loss, the need for blood transfusions, and hypoxic stress ...
Yuanyuan Wang, Yuanyuan Wang, Zhengxiu Sun, Zhengxiu Sun, Yongao Lin, Yongao Lin, Mingshu Tao, Mingshu Tao, Wenxin Zhao, Wenxin Zhao, Jinling Liu, Jinling Liu, Xiaoqin Guo, Xiaoqin Guo, Chuyu Hang, Chuyu Hang, Mingyuan Wang, Mingyuan Wang, Wen Tan, Wen Tan, Xingyu Xiong, Xingyu Xiong, Jun-Li Cao, Jun-Li Cao, He Liu, He Liu, He Liu, He Liu   +27 more
doaj   +1 more source