Results 111 to 120 of about 1,330,663 (304)

Bidirectional Pathological Axis Between Alzheimer's Disease and Circadian Rhythm Disturbance: Mechanisms and Therapeutic Strategies

open access: yesiNew Medicine, EarlyView.
This graphical abstract illustrates a bidirectional vicious cycle between Alzheimer’s disease (AD) and circadian rhythm disturbance (CRD). On the one hand, AD pathology, including amyloid‐β (Aβ) plaque deposition and tau hyperphosphorylation, may damage the suprachiasmatic nucleus (SCN) and disrupt melatonin signaling, leading to sleep fragmentation ...
Jiajia Qin   +10 more
wiley   +1 more source

Antidepressant-treated patients in ambulatory care long-term use of non-psychotropic and psychotropic drugs

open access: yes, 1996
Background. Despite the problems involved in treating depression and concomitant medical disease, there are virtually no longitudinal studies on drug utilisation among depressed patients.MethodUse of prescription drugs among all first-time users of ...
Smedby, Björn,   +11 more
core   +1 more source

Psychotropic drugs and accidents in Scania, Sweden.

open access: yes, 2011
BACKGROUND: Injuries are second to cardiovascular diseases, the main cause of hospital care in Sweden. The aim of the present study was to investigate the associations between medication with psychotropic drugs and injuries from two types of accidents, i.
Merlo, Juan   +12 more
core   +2 more sources

Divergent input patterns to the central lateral amygdala play a duet in fear memory formation

open access: yesiScience
Summary: Somatostatin (SOM)-expressing neurons in the central lateral amygdala (CeL) are responsible for fear memory learning, but the circuit and molecular mechanisms underlying this biology remain elusive.
Jing-hua Gao   +9 more
doaj   +1 more source

Potential Neuroendocrine Disruption by Benzodiazepines and Its Impact on Male Fertility

open access: yesJournal of Applied Toxicology, EarlyView.
ABSTRACT Neuroactive substances have emerged as potent endocrine disruptors affecting male reproductive health through central and peripheral mechanisms. Among these, benzodiazepines, which are widely used for the management of anxiety, insomnia, epilepsy, and neuromuscular disorders, are known as GABA A (gamma‐aminobutyric acid type A) receptor ...
Ana Clara Melo Andrade de Rodrigues   +3 more
wiley   +1 more source

Pregnancy and psychotropic drugs

open access: yes, 2017
Pregnancy is considered a vulnerable period for women affected by a psychopathological condition or generally puts women at a higher risk of developing a psychiatric disorder.
Cesario Bellantuono, Laura Orsolini
core  

The chromatographic identification of psychotropic drugs

open access: yes, 1969
The thin-layer chromatography of three classes of psychotropic drugs—phenethylamines, tryptamines and erganes—has been investigated. Published methods are reviewed and Rf data, normalized by a graphical technique, are reported for extensions and ...
Jane Gardiner, G F Phillips
core   +1 more source

Body weight in autism spectrum disorder: A systematic review and meta‐analysis

open access: yesJCPP Advances, EarlyView.
Abstract Background Evidence on the relationship of autism spectrum disorder (ASD) to overweight/obesity and underweight is mixed. Moreover, it is unclear how this relationship changes with age. Methods We carried out a systematic review (SR) with meta‐analysis on the association between ASD and obesity, overweight and underweight across the life span.
Victoria Nieuwenhuys‐Ruiz   +8 more
wiley   +1 more source

Incidence of self poisoning in patients prescribed psychotropic drugs.

open access: yes, 2009
The drugs most commonly used in self poisoning are the psychotropics, but the proportion of patients given these drugs who take overdoses is unknown. In a prospective study of 43117 people in Oxfordshire, prescriptions issued by general practitioners ...
S M Richards, D C Skegg, K Skegg
core   +1 more source

Assessment of Potential Drug–Drug Interactions of Psycholeptics and Antidepressants in Outpatient Settings

open access: yesPharmacy
Mental health is an important segment in preserving overall health and represents a significant public health issue. In modern times, mental health disorders have risen, often requiring complex pharmacotherapy and chronic monitoring.
Iva Marović   +3 more
doaj   +1 more source

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