Results 91 to 100 of about 100,757 (302)

Joint versus separate inpatient rehabilitation treatment for patients with alcohol use disorder or drug use disorder : an observational study [PDF]

, 2018
Background: In many national treatment systems, patients with alcohol use disorders (AUD) and those with drug use disorders (DUD) are treated separately, while other systems provide joint treatment for both kinds of substance use disorders (SUDs ...
Bender, Stefan, Buchholz, Angela, Heinz, Thomas, Holscher, Frank, Rist, Fred, Scherbaum, Norbert, Schifano, Fabrizio, Specka, Michael   +7 more
core   +2 more sources

Diffusion of Carbamazepine in Hydrophobic Zeolites: A Comparative Study Using Classical and Machine‐Learned Potentials

Chemistry – A European Journal, EarlyView.
Can hydrophobic, shape‐selective zeolites efficiently remove the persistent pharmaceutical CBZ from water? This work moves beyond the static picture of interaction energies by modeling diffusion with umbrella sampling and machine‐learned potentials. Even high intrinsic diffusion barriers can be overcome through exergonic adsorption from water, yielding
Jakob Brauer, Richard Kendra, Carlos Bornes, Lukáš Grajciar, Michael Fischer   +4 more
wiley   +1 more source

A Novel Workflow for Fast Elucidation of Drug Metabolites for Screening—Combining In Silico Metabolite Prediction With Trapped Ion Mobility QTOF‐MS

Drug Testing and Analysis, EarlyView.
UHPLC‐timsTOF‐MS with in silico prediction and automated annotation enabled rapid identification of quetiapine metabolites from pHLMs, facilitating their inclusion in targeted LC‐QTOF‐MS urine screening and improving biomarker detection for toxicological applications.
Annette Zschiesche, Birgit Schneider, Ilona Nordhorn, Carsten Baessmann, Laura M. Huppertz, Jürgen Kempf   +5 more
wiley   +1 more source

‘From Badness to Sickness’ and Back Again: The Use of Medication in the U.S. School and Foster Care Systems [PDF]

, 2018
This article explores the over- and under-prescription of psychotropic medication to youth of color both in public schools and the foster care system. Under the umbrella of the schools-to-prison pipeline, there is a wide array of literature addressing ...
Nemetz, Sarah J.
core   +1 more source

Effect of Reaction Time and Temperature on the Impurity Profile of Amphetamine in the Leuckart Method

Drug Testing and Analysis, EarlyView.
This study investigates the effect of the reaction temperature (step 1) and reaction time (step 1 and 2) on the conversion efficiency and impurity profile of amphetamine synthesized via the Leuckart method. Conversion efficiency and impurity profile were assessed using gas chromatography–flame ionization detection (GC–FID) and GC–mass spectrometry (GC ...
Maartje C. M. Verhoeven, Robert C. Huls, Nelly W. van der Stelt, Jelle C. de Koning, Marco van Grol, Ruben F. Kranenburg, Arian C. van Asten, Janneke W. Hulshof   +7 more
wiley   +1 more source

MOTS-c is an effective target for treating cancer-induced bone pain through the induction of AMPK-mediated mitochondrial biogenesis

Acta Biochimica et Biophysica Sinica
Bone cancer pain (BCP), due to cancer bone metastasis and bone destruction, is a common symptom of tumors, including breast, prostate, and lung tumors. Patients often experience severe pain without effective treatment.
Yang Long, Li Miaomiao, Liu Yucheng, Bai Yang, Yin Tianyu, Chen Yangyang, Jiang Jinhong, Liu Su   +7 more
doaj   +1 more source

Zebrafish Behavioral Profiling Links Drugs to Biological Targets and Rest/Wake Regulation [PDF]

, 2010
A major obstacle for the discovery of psychoactive drugs is the inability to predict how small molecules will alter complex behaviors. We report the development and application of a high-throughput, quantitative screen for drugs that alter the behavior ...
Arvanites, Anthony, Haggarty, Stephen J., Jang, Sumin, Kokel, David, Lam, Kelvin, Peterson, Randall T., Prober, David A., Rihel, Jason, Rubin, Lee L., Schier, Alexander F., Zimmerman, Steven   +10 more
core   +1 more source

Chemical Straightening as a Source of Analytical Variability in Hair Testing: A Dual‐Analyte Case Report

Drug Testing and Analysis, EarlyView.
ABSTRACT Hair analysis is increasingly used in forensic toxicology; however, result interpretation may be influenced by cosmetic hair treatments. Although the effects of bleaching, dyeing, and thermal straightening have already been evaluated, data on permanent chemical hair straightening are scarce, particularly under in vivo conditions.
Miriam Blanco‐Ces, Ana de‐Castro‐Ríos, María Cobo‐Golpe, Ángela López‐Rabuñal, Angelines Cruz, Elena Lendoiro   +5 more
wiley   +1 more source

Identification and Characterization of the Designer Opioid N‐Pyrrolidino Fluetonitazene in Nasal Spray

Drug Testing and Analysis, EarlyView.
N‐Pyrrolidino fluetonitazene, a synthetic opioid, was identified and characterized in a nasal spray using GC‐MS, LC‐QTOF‐MS, NMR and FT‐IR. ABSTRACT Detection of drugs in non‐biological samples serves as a fundamental basis for identifying emerging trends in the field of new psychoactive substances and provides valuable information for optimizing ...
Fabian Picht, Valentin Cepus, Rona Hohlfeld, Julian Klingbeil, Marco Weber   +4 more
wiley   +1 more source

Efficacy of transcranial direct current stimulation for improving postoperative quality of recovery in elderly patients undergoing lower limb major arthroplasty: a randomized controlled substudy

Frontiers in Neurology
BackgroundPrevious studies have demonstrated improvements in motor, behavioral, and emotional areas following transcranial direct current stimulation (tDCS), but no published studies have reported the efficacy of tDCS on postoperative recovery quality in
Mingshu Tao, Mingshu Tao, Jie Yang, Jie Yang, Rongguang Liu, Rongguang Liu, Song Zhang, Yuan Han, Chunyan Li, Chunyan Li, Qi Wei, Qi Wei, Dexian Chen, Dexian Chen, Jiaxing Fang, Jiaxing Fang, Hongxing Zhang, Yuwei Wang, He Liu, He Liu, He Liu, He Liu, Jun-Li Cao, Jun-Li Cao   +23 more
doaj   +1 more source