Results 71 to 80 of about 1,082,361 (305)

Exploring new avenues: Psychedelic‐assisted therapy for young people

British Journal of Clinical Pharmacology, EarlyView.
Rates of mental illness in young people are increasing, whereas the development of novel mental health treatments has not significantly progressed. Psychedelic‐assisted therapy, using substances such as psilocybin and 3,4‐methylenedioxymethamphetamine (MDMA), has shown potential in the treatment of mental illnesses in the adult population, including ...
Ioanna Artemis Vamvakopoulou, Dasha Nicholls, David J. Nutt, Martina Di Simplicio   +3 more
wiley   +1 more source

The use of psychotropic drugs in renal diseases

, 2017
The use of psychotropic drugs in patients with renal impairment is one of the main challenges of clinicians, as some of the drugs are metabolized or excreted through the kidneys.
Eker, Salih Saygın
core  

An ETH‐LAD trip with unfavourable consequences: A case report

British Journal of Clinical Pharmacology, EarlyView.
Numerous analogues of the psychedelic and internationally controlled hallucinogen LSD have been described; however, only a limited number have been systematically investigated. This report presents the first case with an analytically confirmed ingestion of ETH‐LAD (6‐ethyl‐6‐nor‐lysergic acid diethylamide), the N‐ethyl derivative of LSD.
Johannes Nadler, Michaela Sommer, Annette Zschiesche, Anne Stürzebecher, Christina Grumann, Volker Auwärter, Maren Hermanns‐Clausen   +6 more
wiley   +1 more source

Dysfunctional S1P/S1PR1 signaling in the dentate gyrus drives vulnerability of chronic pain-related memory impairment

eLife
Memory impairment in chronic pain patients is substantial and common, and few therapeutic strategies are available. Chronic pain-related memory impairment has susceptible and unsusceptible features.
Mengqiao Cui, Xiaoyuan Pan, Zhijie Fan, Shulin Wu, Ran Ji, Xianlei Wang, Xiangxi Kong, Zhou Wu, Lingzhen Song, Weiyi Song, Jun-Xia Yang, Hongjie Zhang, Hongxing Zhang, Hai-Lei Ding, Jun-Li Cao   +14 more
doaj   +1 more source

The impact of pharmacogenetic‐informed care on medication adherence and psychological factors associated with adherence: A narrative review

British Journal of Clinical Pharmacology, EarlyView.
Improvement in medication adherence is often proposed as a potential advantage of pharmacogenetic‐guided prescribing over a traditional one‐size‐fits‐all approach. This paper provides a review of the published literature and presents the findings of studies that measure adherence to medication as an outcome of pharmacogenetic‐informed care, or that ...
Lucy Galloway, Alison Wright, John Weinman   +2 more
wiley   +1 more source

How did the use of psychotropic drugs change during the Great Recession in Portugal? A follow-up to the National Mental Health Survey

BMC Psychiatry, 2020
Background Research suggests that economic recessions might be associated with a higher use of psychotropic drugs, but literature is scarce and contradictory in identifying the most vulnerable groups. This study aims to assess possible changes in the use
Manuela Silva, Ana Antunes, Sofia Azeredo-Lopes, Graça Cardoso, Miguel Xavier, Benedetto Saraceno, José Miguel Caldas-de-Almeida   +6 more
doaj   +1 more source

Side effects of psychotropic drugs on eye [PDF]

, 2021
A.A. Petukhova1, A.A. Panov1, Ya.V. Malygin2, M.A. Kazanfarova3 1Lomonosov Moscow State University, Moscow, Russian Federation 2A.I. Evdokimov Moscow University of Medicine and Dentistry, Moscow, Russian Federation 3Skolkovo Innovation ...
A.A. Panov, A.A. Petukhova, M.A. Kazanfarova, Ya.V. Malygin   +3 more
core   +1 more source

Pharmacokinetics and safety of a modified‐release psilocybin formulation: A SAD Phase I trial in normal‐weight and overweight/obese participants

British Journal of Clinical Pharmacology, EarlyView.
Aims This study aimed to evaluate the safety, tolerability and pharmacokinetics of a novel oral modified‐release psilocybin formulation (REL‐P11) in normal‐weight and overweight/obese healthy adults and to assess its suitability for controlled, subperceptual exposure, in light of emerging evidence supporting serotonergic modulation in metabolic ...
Anna Signor, Stefano Comai, Gianfranco Pasut, Franco Folli, Marco Gentilucci, Negar Gharavi, Sofia Raitsin, Thuy Van Nguyen, Marco Pappagallo, Andrea Mattarei, Paolo L. Manfredi, Sara De Martin   +11 more
wiley   +1 more source

Chronic alcohol exposure contributes to postoperative cognitive dysfunction via NR2B upregulation in the hippocampus of adult mice

Translational Psychiatry
Postoperative cognitive dysfunction (POCD) is a common perioperative complication of the central nervous system, and patients with chronic alcohol exposure frequently require surgery under anesthesia. However, the contribution of chronic alcohol exposure
Linhui Ma, Shuai Li, Wei Dong, Jie Wan, Zhichao Li, Chudi Zhang, Xinjie Zhou, Zhifan Wang, Chenghua Zhou, Yuqing Wu, Hui Zheng   +10 more
doaj   +1 more source

Anesthetic-mediated cardioprotection: from molecular mechanisms to clinical translation challenges

Frontiers in Physiology
Anesthetics have long been recognized as essential pharmacological agents for surgical procedures, primarily valued for their ability to induce unconsciousness and provide analgesia.
Tingting Fu, Xiao Jia, Can Tang, Dan Yu, Hui Zhou, Xinghe Wang, Xinghe Wang, Su Liu, Su Liu, Kunwei Wu, Kunwei Wu   +10 more
doaj   +1 more source