Results 61 to 70 of about 1,330,663 (304)

Psychotropic Drugs [PDF]

BMJ, 1967
  +7 more sources

RNF168 dephosphorylation ameliorates cognitive decline in Aβ-based mouse models of Alzheimer’s disease

Acta Neuropathologica Communications
Alzheimer’s disease (AD) is the most prevalent neurodegenerative disorder among the elderly, with limited effective treatments available in clinical practice.
Miao-Jin Ji, Yun Li, Jiao Yang, Kangjunjie Wang, Shuning Sang, Hong Yang, Chenhao Tian, Xin Tang, Ji-Heng Cai, Tianhan He, Cheng Zhang, Huanyao Tang, Tiantao Cui, Xinran Meng, Xiang Cao, Jiaqi Zhu, Jie Wang, Jun-Li Cao, Daming Gao, Chao Liu   +19 more
doaj   +1 more source

Trends and patterns of antipsychotic medication use during pregnancy: A population‐based study

British Journal of Clinical Pharmacology, EarlyView.
Aim The prescription of antipsychotic medication during pregnancy, particularly second‐generation antipsychotics, has increased in several countries in recent decades. This population‐based study investigated trends and patterns in antipsychotic medication use during pregnancy between 2011 and 2023 in Northern Ireland (NI), UK.
Dervla Quinn, Michael Donnelly, Neil Heron, Joseph Kane, Lisa Kent, Fionnuala Mone, Ciaran O'Neill   +6 more
wiley   +1 more source

Propofol for depression: mechanisms and therapeutic potential

Frontiers in Physiology
Propofol, one of the most widely used intravenous anesthetics, is undergoing a transformative identity shift from a purely surgical agent to a potential therapeutic tool for neuropsychiatric disorders.
Dan Yu, Ye Liao, Jie Li, Aiqiu Zheng, Xin Meng, Shumin Gong, Can Li, Kunwei Wu, Kunwei Wu   +8 more
doaj   +1 more source

Motor Physiology Transcranial Magnetic Stimulation–Based Biomarkers and Associated Neurocognitive Profiles in Attention‐Deficit/Hyperactivity Disorder

Annals of the Child Neurology Society, EarlyView.
ABSTRACT Purpose Attention‐deficit/hyperactivity disorder (ADHD) is a highly prevalent and heterogeneous neurodevelopmental condition for which current diagnostic approaches rely on symptom‐based classifications that do not capture underlying neurobiology.
Alyssa C. DeRonda, Alice Sperry, Deana Crocetti, Karlee Migneault, Paul S. Horn, Donald L. Gilbert, Keri S. Rosch, Stewart H. Mostofsky   +7 more
wiley   +1 more source

How to Optimize Healthy Volunteer Screening and Enrolment in Clinical Trials: A Qualitative and Quantitative Approach to Evaluate Processes and Healthy Volunteers' Perceptions

Clinical Pharmacology &Therapeutics, EarlyView.
Healthy volunteers (HVs) are essential for phase I trials, yet their recruitment and screening remain resource‐intensive and ethically complex. High screening failure (SF) rates highlight the need to evaluate and understand all aspects of the enrolment processes. We analyzed SF patterns in a large German HV cohort and explored participants' motivations,
Evelyn Krohmer, Manuela König, Cathrin J. Vogt, Marina Streckebein, Sybille Baumann, Max Blumenstock, Ruwen Böhm, Fabian Müller, Nadja Struß, Viktoria S. Wurmbach, Antje Blank   +10 more
wiley   +1 more source

Psychotropic drugs and bone [PDF]

The purpose of this article is to provide an overview of the effects of psychotropic medications on bone metabolism, bone mineral density (BMD), and fracture risk. Methods. The literature search was carried out in PubMed.
R.W. Gasser, H. Resch
core   +1 more source

Galactorrhea Due to Psychotropic Drugs

Pharmacopsychiatry, 2004
Within the drug safety program in psychiatry AMSP ( Arzneimittelsicherheit in der Psychiatrie), severe adverse drug reactions (ADRs) are assessed. Currently 35 psychiatric hospitals and departments are participating in detecting severe ADRs. This paper focuses on prolactin-dependent ADRs such as gynecomastia and galactorrhea due to psychotropic ...
Kropp, Silke, Ziegenbein, M., Grohmann, Renate, Engel, Rolf R., Degner, Detlef   +4 more
openaire   +3 more sources

Medication Use During Breastfeeding—An Understudied Population: A Five‐Year Experience in the Pharmacovigilance Center of Lyon

Clinical Pharmacology &Therapeutics, EarlyView.
Medication use during breastfeeding is common, yet data on drug transfer into breast milk and infant exposure remain limited. This study describes real‐world requests concerning medication compatibility with breastfeeding managed by the Lyon pharmacovigilance center over five years.
Blandine Bertin, Aurore Gouraud, Anthony Facile, Fanny Ledys, Sabrina Pierre, Véronique Pizzoglio, Thierry Vial, Marine Auffret, Marina Atzenhoffer   +8 more
wiley   +1 more source

Psychotropic drugs and sleep

, 2017
In humans, the cycle of sleep-wakefulness has a daily rhythm called the circadian rhythm. The effects of psychotropics on biological rhythmicity can occur via possible neurotransmitter and neuromediator mechanisms within a relatively short time period ...
Aydin A., Tekdemir R., Selvi Y.
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