Longitudinal study of gut microbiome in obsessive-compulsive disorder. [PDF]
The diversity, composition, and functional profile of the gut microbiome in patients with obsessive–compulsive disorder did not differ significantly from healthy controls and remained stable over time, despite behavioral changes after exposure and response prevention therapy. Abstract Introduction Patients with obsessive–compulsive disorder (OCD) often
Chen LL +5 more
europepmc +2 more sources
Intergenerational Transmission of Valence Bias Is Moderated by Attachment. [PDF]
ABSTRACT There are individual differences in how people respond to emotionally ambiguous cues (i.e., valence bias), which have important consequences for mental health, development, and social functioning, yet how these differences develop in childhood and adolescence is unknown.
Humphries A +5 more
europepmc +2 more sources
Longitudinal Trajectory of Cognition, Brain Morphometry, and Brain Predicted Age in Unaffected First-Degree Relatives of Patients With Bipolar Disorder. [PDF]
ABSTRACT Introduction Prior research suggests structural brain abnormalities and cognitive difficulties in patients with bipolar disorder. Although there is some evidence that similar structural and cognitive changes may also be present in unaffected relatives (UR) of patients with bipolar disorder, it is not known whether they remain static or ...
Kjærstad HL +11 more
europepmc +2 more sources
Using computer vision of facial expressions to assess symptom domains and treatment response in antipsychotic-naïve patients with first-episode psychosis. [PDF]
Abstract Background Facial expressions are a core aspect of non‐verbal communication. Reduced emotional expressiveness of the face is a common negative symptom of schizophrenia, however, quantifying negative symptoms can be clinically challenging and involves a considerable element of rater subjectivity.
Ambrosen KS +5 more
europepmc +2 more sources
Childhood maltreatment and self-hatred as distinguishing characteristics of psychiatric patients with self-harm: A comparison with clinical and healthy controls. [PDF]
Abstract Introduction Deliberate self‐harm (DSH) is common in clinical populations. Childhood maltreatment (CM) and attitudes both towards oneself and towards DSH may be of importance for the development of DSH. This study aimed to test whether patients with DSH report more CM, more negative attitudes towards oneself and more positive attitudes towards
Nilsson M, Lundh LG, Westling S.
europepmc +2 more sources
Use of GLP-1 receptor agonists and subsequent risk of alcohol-related events. A nationwide register-based cohort and self-controlled case series study. [PDF]
Abstract Animal studies have related glucagon‐like peptide 1 receptor agonists (GLP‐1) to lower alcohol intake. We examined whether GLP‐1 was associated with risk of alcohol‐related events in a nationwide cohort study and a self‐controlled case series analysis including all new users of GLP1 (n = 38 454) and dipeptidyl peptidase 4 inhibitors (DPP4) (n =
Wium-Andersen IK +5 more
europepmc +2 more sources
Aim The disrupted‐in‐schizophrenia 1 (DISC1) protein is a key regulator at the intersection of major signaling pathways relevant for adaptive behavior. It is prone to posttranslational changes such as misassembly and aggregation but the significance of such transformations for human mental illness has remained unclear.
Marlene Pils +11 more
wiley +1 more source
Patterns of maladaptive exercise behavior from ages 14–24 in a longitudinal cohort
Background Exercise for weight loss and maladaptive exercise (exercise that results in negative consequences or interference with daily life) are common behaviors among youth and are associated with increased risk of disordered eating symptoms. The current study clarifies processes that influence exercise‐related risk in adolescence and young adulthood,
Katherine Schaumberg +2 more
wiley +1 more source
Abstract This article analyses the ideological, political and medical positioning of mentally ill veterans of the Finnish Civil War of 1918 in inter‐war Finland. Using pension applications, the writings of veteran activists, parliamentary debates, psychiatric examinations and military documents this article shows that war‐related mental disability was ...
VIRVA LISKI
wiley +1 more source
Abstract Objective To evaluate the feasibility and efficacy of ACT‐enhanced Group Behavior Therapy (AEGBT) for mixed diagnosis groups including patients with trichotillomania (TTM) and skin‐picking disorder (SPD) in routine psychiatric care. Method Adult patients (N = 40) with TTM and/or SPD received 10 weeks of AEGBT followed by five booster sessions.
Mia Asplund +6 more
wiley +1 more source

