Results 11 to 20 of about 304 (171)

Exploring the Associations Between Affective and Non-Affective Cognitive Domains in Mood Disorders and Healthy Controls Using Network Analysis. [PDF]

Acta Psychiatr Scand
ABSTRACT Introduction Cognitive impairment is a core feature of mood disorders that contributes to reduced functioning and poorer prognosis, thereby emerging as an important treatment target. Persistent trait‐related impairments present within both affective and non‐affective cognition. Nevertheless, the relationship between affective and non‐affective
Kjærstad HL, Iversen AE, Vinberg M, Kessing LV, Zarp J, Miskowiak KW.   +5 more
europepmc   +2 more sources

Longitudinal Trajectory of Cognition, Brain Morphometry, and Brain Predicted Age in Unaffected First-Degree Relatives of Patients With Bipolar Disorder. [PDF]

Bipolar Disord
ABSTRACT Introduction Prior research suggests structural brain abnormalities and cognitive difficulties in patients with bipolar disorder. Although there is some evidence that similar structural and cognitive changes may also be present in unaffected relatives (UR) of patients with bipolar disorder, it is not known whether they remain static or ...
Kjærstad HL, Macoveanu J, Ysbæk-Nielsen AT, Damgaard V, Frangou S, Knudsen GM, Coello K, Stanislaus S, Faurholt-Jepsen M, Vinberg M, Kessing LV, Miskowiak KW.   +11 more
europepmc   +2 more sources

Intergenerational Transmission of Valence Bias Is Moderated by Attachment. [PDF]

Dev Sci
ABSTRACT There are individual differences in how people respond to emotionally ambiguous cues (i.e., valence bias), which have important consequences for mental health, development, and social functioning, yet how these differences develop in childhood and adolescence is unknown.
Humphries A, Peckinpaugh I, Kupka G, Blair RJR, Tottenham N, Neta M.   +5 more
europepmc   +2 more sources

Longitudinal study of gut microbiome in obsessive-compulsive disorder. [PDF]

Brain Behav, 2023
The diversity, composition, and functional profile of the gut microbiome in patients with obsessive–compulsive disorder did not differ significantly from healthy controls and remained stable over time, despite behavioral changes after exposure and response prevention therapy. Abstract Introduction Patients with obsessive–compulsive disorder (OCD) often
Chen LL, Abbaspour A, Aspvall K, Rück C, Bulik CM, Pascal D.   +5 more
europepmc   +2 more sources

Self-Reported Burden Among Informal Caregivers of Patients Receiving Psychiatric Hospital Treatment: A National Cross-Sectional Study. [PDF]

Int J Ment Health Nurs
ABSTRACT Involving informal caregivers in the support of patients receiving psychiatric treatment has a positive effect on the patient's treatment outcome. At the same time, providing care for these patients may pose a serious burden on the caregivers themselves.
Thygesen M, Nielsen BK, Ellegaard T, Nielsen LA, Hald SR, Eckardt JP, Svendsen ML.   +6 more
europepmc   +2 more sources

Using computer vision of facial expressions to assess symptom domains and treatment response in antipsychotic-naïve patients with first-episode psychosis. [PDF]

Acta Psychiatr Scand
Abstract Background Facial expressions are a core aspect of non‐verbal communication. Reduced emotional expressiveness of the face is a common negative symptom of schizophrenia, however, quantifying negative symptoms can be clinically challenging and involves a considerable element of rater subjectivity.
Ambrosen KS, Lemvigh CK, Nielsen MØ, Glenthøj BY, Syeda WT, Ebdrup BH.   +5 more
europepmc   +2 more sources

Disrupted‐in‐schizophrenia 1 protein aggregates in cerebrospinal fluid are elevated in patients with first‐episode psychosis

Psychiatry and Clinical Neurosciences, Volume 77, Issue 12, Page 665-671, December 2023., 2023
Aim The disrupted‐in‐schizophrenia 1 (DISC1) protein is a key regulator at the intersection of major signaling pathways relevant for adaptive behavior. It is prone to posttranslational changes such as misassembly and aggregation but the significance of such transformations for human mental illness has remained unclear.
Marlene Pils, Julia Rutsch, Feride Eren, Göran Engberg, Fredrik Piehl, Simon Cervenka, Carl Sellgren, Svenja Troßbach, Dieter Willbold, Sophie Erhardt, Oliver Bannach, Carsten Korth   +11 more
wiley   +1 more source

Patterns of maladaptive exercise behavior from ages 14–24 in a longitudinal cohort

Journal of Child Psychology and Psychiatry, Volume 64, Issue 11, Page 1555-1568, November 2023., 2023
Background Exercise for weight loss and maladaptive exercise (exercise that results in negative consequences or interference with daily life) are common behaviors among youth and are associated with increased risk of disordered eating symptoms. The current study clarifies processes that influence exercise‐related risk in adolescence and young adulthood,
Katherine Schaumberg, Cynthia M. Bulik, Nadia Micali   +2 more
wiley   +1 more source

Use of GLP‐1 receptor agonists and subsequent risk of alcohol‐related events. A nationwide register‐based cohort and self‐controlled case series study

Basic &Clinical Pharmacology &Toxicology, Volume 131, Issue 5, Page 372-379, November 2022., 2022
Abstract Animal studies have related glucagon‐like peptide 1 receptor agonists (GLP‐1) to lower alcohol intake. We examined whether GLP‐1 was associated with risk of alcohol‐related events in a nationwide cohort study and a self‐controlled case series analysis including all new users of GLP1 (n = 38 454) and dipeptidyl peptidase 4 inhibitors (DPP4) (n =
Ida Kim Wium‐Andersen, Marie Kim Wium‐Andersen, Anders Fink‐Jensen, Jørgen Rungby, Martin Balslev Jørgensen, Merete Osler   +5 more
wiley   +1 more source

Childhood maltreatment and self‐hatred as distinguishing characteristics of psychiatric patients with self‐harm: A comparison with clinical and healthy controls

Clinical Psychology &Psychotherapy, Volume 29, Issue 5, Page 1778-1789, September/October 2022., 2022
Abstract Introduction Deliberate self‐harm (DSH) is common in clinical populations. Childhood maltreatment (CM) and attitudes both towards oneself and towards DSH may be of importance for the development of DSH. This study aimed to test whether patients with DSH report more CM, more negative attitudes towards oneself and more positive attitudes towards
Magnus Nilsson, Lars‐Gunnar Lundh, Sofie Westling   +2 more
wiley   +1 more source