Results 1 to 10 of about 5,628 (162)

Clinicopathological comparison between PTCL‐TBX21 and PTCL‐GATA3 in Japanese patients

Cancer Medicine
Aim Peripheral T‐cell lymphoma not otherwise specified (PTCL‐NOS) is a heterogeneous disease that can be classified into the PTCL‐TBX21 and PTCL‐GATA3 subtypes. Methods In this study, we compared the clinicopathological features of PTCL‐NOS in a Japanese
Yasumasa Shimasaki, Hiroaki Miyoshi, Teppei Imamoto   +2 more
exaly   +5 more sources

PTCL, NOS: An update on classification, risk-stratification, and treatment

Frontiers in Oncology, 2023
The peripheral T-cell lymphomas (PTCL) are relatively rare, heterogeneous, and therapeutically challenging. While significant therapeutic gains and improved understanding of disease pathogenesis have been realized for selected PTCL subtypes, the most ...
Jonathan Weis, John C Reneau, Ryan A Wilcox   +2 more
exaly   +5 more sources

Peripheral T-cell Lymphoma in Japan: Real-World Patient Characteristics, Treatment Patterns, Healthcare Resource Utilization, and Costs [PDF]

Journal of Health Economics and Outcomes Research
# Background Peripheral T-cell lymphomas (PTCLs) are a rare and heterogeneous group of non-Hodgkin lymphomas associated with aggressive clinical course and suboptimal outcomes.
Charles Dharmani, Oluwatosin Fofah, Pingping Qu, Zoe Jiang, Jingjian Wang, Li Li, Yijing Tao, Lin Song   +7 more
doaj   +2 more sources

ENO1 inhibition synergizes with chidamide to induce ferroptosis in PTCL-NOS through metabolic remodeling [PDF]

Blood Science
Enolase (ENO1) is a key enzyme involved in glycolysis and plays an important role in various types of cancer. This study explored the role and mechanism of ENO1 and the histone deacetylase inhibitor chidamide in peripheral T cell lymphoma, not otherwise ...
Feng Zhu, Mingxi Tian, Keyi Lu, Cong Wang, Jiao Liu, Xinyi Li, Xuejiao Gu, Bin Lv, Ziqing Huang, Lingyu Zeng, Zhenyu Li, Hailong Lu, Kailin Xu   +12 more
doaj   +2 more sources

Immune pathway upregulation and lower genomic instability distinguish EBV-positive nodal T/NK-cell lymphoma from ENKTL and PTCL-NOS

Haematologica, 2022
Primary Epstein-Barr virus (EBV)-positive nodal T/NK-cell lymphoma (PTCL-EBV) is a poorly understood disease which shows features resembling extranodal NK/T-cell lymphoma (ENKTL) and is currently not recognized as a distinct entity but categorized as a ...
Cho Mar Myint Wai, Shangying Chen, The Phyu, Shuangyi Fan, Sai Mun Leong, Wenning Zheng, Louis Ching Yi Low, Shoa-Nian Choo, Chi-Kuen Lee, Tae-Hoon Chung, Kenneth Hon Kim Ban, Soumita Ghosh, Stefanus Lie, Seiichi Kato, Shigeo Nakamura, Emiko Takahashi, Young-Hyeh Ko, Joseph D. Khoury, Shih-Sung Chuang, Rex K.H. Au-Yeung, Soo-Yong Tan, Soon-Thye Lim, Choon-Kiat Ong, Yong-Howe Ho, Li Mei Poon, Sanjay de Mel, Anand D. Jeyasekharan, Wee-Joo Chng, Franziska Otto, Leticia Quintanilla-Martinez, Federica Zanardi, Fabio Iannelli, Claudio Tripodo, Jason J. Pitt, Siok-Bian Ng   +34 more
doaj   +1 more source

Comprehensive analysis of clinical, pathological, and genomic characteristics of follicular helper T-cell derived lymphomas

Experimental Hematology & Oncology, 2021
Background The 2016 World Health Organization (WHO) classification introduced nodal lymphomas of T follicular helper (Tfh) cell origin, such as angioimmunoblastic T-cell lymphoma (AITL), follicular peripheral T-cell lymphoma (F-PTCL), and nodal ...
Sang Eun Yoon, Junhun Cho, Yeon Jeong Kim, Young Hyeh Ko, Woong-Yang Park, Seok Jin Kim, Won Seog Kim   +6 more
doaj   +1 more source

Does organizational justice enhance job performance through high-performance human resource practices?

WPOM : Working Papers on Operations Management, 2021
This study aims to analyze the influence of organizational justice (OJ) on job performance (JP) intention via the mediating influence of high-performance human resource practices (HPHRPs) in a developing context.
Ali Zeb, Fazal Ur Rehman, Yasin Arsalan, Muhammad Usman Khan   +3 more
doaj   +1 more source

Is the Optimal Timing First Complete Remission for Autologous Stem Cell Transplantation in Patients with Peripheral T-Cell Lymphoma?

Namık Kemal Tıp Dergisi, 2021
Aim:Outcome for most patients with peripheral T cell lymphomas (PTCLs) is poor, with low response rates and short durations of remission. We aim to analyze the outcome of PTCL patients who underwent autologous stem cell transplantation (ASCT) at our ...
Bahar UNCU ULU, Derya ŞAHİN, Tuğçe Nur YİĞENOĞLU, Merih KIZIL ÇAKAR, Mehmet Sinan DAL, Fevzi ALTUNTAŞ   +5 more
doaj   +1 more source

Expression of telomerase reverse transcriptase in peripheral T‐cell lymphoma

Cancer Medicine, 2021
Telomere length is maintained by the activation of telomerase, which causes continuous cell division and proliferation in many carcinomas. A catalytic reverse transcriptase protein (TERT) encoded by the TERT gene plays a critical role in the activation ...
Fumiko Arakawa, Hiroaki Miyoshi, Noriaki Yoshida, Kazutaka Nakashima, Yosaku Watatani, Takuya Furuta, Kyohei Yamada, Mayuko Moritsubo, Mai Takeuchi, Eriko Yanagida, Yasumasa Shimasaki, Kei Kohno, Keisuke Kataoka, Koichi Ohshima   +13 more
doaj   +1 more source

Efficacy and safety of histone deacetylase inhibitors in peripheral T-cell lymphoma: a systematic review and meta-analysis on prospective clinical trials

Frontiers in Oncology, 2023
BackgroundThe overall survival of peripheral T-cell lymphoma (PTCL) is dismal. Histone deacetylase (HDAC) inhibitors have exhibited promising treatment outcomes for PTCL patients. Therefore, this work aims to systematically evaluate the treatment outcome
Peipei Yang, Yali Tao, Ailin Zhao, Kai Shen, He Li, Jinjin Wang, Hui Zhou, Zhongwang Wang, Mengyao Wang, Ying Qu, Li Zhang, Yuhuan Zheng, Ting Niu   +12 more
doaj   +1 more source