Results 21 to 30 of about 5,648 (180)

Pathobiology of nodal peripheral T-cell lymphomas: current understanding and future directions

Haematologica, 2023
Predominantly nodal is the most common clinical presentation of peripheral T- (and NK-) cell lymphomas (PTCL), which comprise three main groups of diseases: (i) systemic anaplastic large cell lymphomas (ALCL), whether positive or negative for anaplastic
Bettina Bisig, Kerry J. Savage, Laurence de Leval   +2 more
doaj   +1 more source

Rituximab Plus Chemotherapy Provides No Clinical Benefit in a Peripheral T-Cell Lymphoma not Otherwise Specified with Aberrant Expression of CD20 and CD79a: A Case Report and Review of the Literature

Diagnostics, 2020
Peripheral T-cell lymphoma, not otherwise specified (PTCL-NOS) is the most common entity of mature T-cell neoplasms. PTCL-NOS generally has an aggressive behavior and is often refractory to standard therapy.
Alessandro Mangogna, Maria Christina Cox, Luigi Ruco, Gianluca Lopez, Beatrice Belmonte, Arianna Di Napoli   +5 more
doaj   +1 more source

A preclinical model of peripheral T‐cell lymphoma GATA3 reveals DNA damage response pathway vulnerability

EMBO Molecular Medicine, 2022
Peripheral T‐cell lymphoma (PTCL) represents a rare group of heterogeneous diseases in urgent need of effective treatments. A scarcity of disease‐relevant preclinical models hinders research advances.
Elizabeth A Kuczynski, Giulia Morlino, Alison Peter, Anna M L Coenen‐Stass, Jennifer I Moss, Neha Wali, Oona Delpuech, Avinash Reddy, Anisha Solanki, Charles Sinclair, Dinis P Calado, Larissa S Carnevalli   +11 more
doaj   +1 more source

Fusion transcripts FYN-TRAF3IP2 and KHDRBS1-LCK hijack T cell receptor signaling in peripheral T-cell lymphoma, not otherwise specified

Nature Communications, 2021
Peripheral T cell lymphoma (PTCL) not otherwise specified (NOS) is a subgroup of PTCL, which has no distinctive features and is poorly characterized at the genetic level.
Koen Debackere, Lukas Marcelis, Sofie Demeyer, Marlies Vanden Bempt, Nicole Mentens, Olga Gielen, Kris Jacobs, Michael Broux, Gregor Verhoef, Lucienne Michaux, Carlos Graux, Iwona Wlodarska, Philippe Gaulard, Laurence de Leval, Thomas Tousseyn, Jan Cools, Daan Dierickx   +16 more
doaj   +1 more source

Clinicopathological implications of immunohistochemical expression of TBX21, CXCR3, GATA3, CCR4, and TCF1 in nodal follicular helper T-cell lymphoma and peripheral T-cell lymphoma, not otherwise specified [PDF]

Journal of Pathology and Translational Medicine
Background The classification of nodal peripheral T-cell lymphoma (PTCL) has evolved according to histology, cell-of-origin, and genetic alterations. However, the comprehensive expression pattern of follicular helper T-cell (Tfh) markers, T-cell factor-1
Bogyeong Han, Sojung Lim, Jeemin Yim, Young Keun Song, Jiwon Koh, Sehui Kim, Cheol Lee, Young A Kim, Yoon Kyung Jeon   +8 more
doaj   +1 more source

Use of ifosfamide, carboplatin and etoposide in combination with brentuximab vedotin or romidepsin based on CD30 positivity in relapsed/refractory peripheral T‐cell lymphoma

Cancer Reports, 2022
Background Relapsed/refractory peripheral T‐cell lymphoma (R/R PTCL) has a poor prognosis. Romidepsin (Ro) and brentuximab vedotin (Bv), combined with ifosfamide, carboplatin, and etoposide (ICE) has not been significantly studied in PTCL.
Cesar Gentille, Humaira Sarfraz, Jitesh Joshi, Jasleen Randhawa, Shilpan Shah, Sai Ravi Pingali   +5 more
doaj   +1 more source

The Intricate Sabatier Optimality of Anion Electroreduction and Its Consequences for Nitrate Reduction

Angewandte Chemie, Volume 138, Issue 26, 22 June 2026.
The Sabatier principle and volcano plots declare that optimal electrocatalysis is found in the middle between strong and weak binding of key intermediates. However, it is shown here that during anion electroreduction, strong and weak binding are potential‐dependent concepts and volcanoes are mobile.
Mattia Salomone, Ioannis Katsounaros, Federico Calle‐Vallejo   +2 more
wiley   +2 more sources

Frequency, distribution, and immunomorphologic characteristics of peripheral T-cell lymphoma, not otherwise specified in a tertiary care center in Southern India

Indian Journal of Pathology and Microbiology, 2018
Aims: In world literature, Peripheral T-cell lymphomas (PTCLs) constituted about 12% of non-Hodgkin's lymphomas (NHL) of which PTCL not otherwise specified (NOS) was the most common subtype.
Archana Lakshmanan, Deeksha Sikri, Sushama Patil, Ann Kurian, S Annapurneswari, Sheila Nair   +5 more
doaj   +1 more source

A case report of double positive peripheral T cell lymphoma- not otherwise specified in a young pregnant female

Indian Dermatology Online Journal, 2022
Peripheral T-cell lymphoma (PTCL) comprises 5–20% of all non-Hodgkin lymphomas (NHL). These all have different morphological patterns, phenotypes, and clinical presentations making it a diverse group of lymphomas. PTCL, not otherwise specified (PTCL-NOS),
Nishi Trivedi, Jigna Padhiyar, Nayan Patel, Sanjay Gandhi   +3 more
doaj   +1 more source

Routes to Cyclobutadiene and Cycloallyl Pt(II) Complexes: Dicationic Bis(Alkyne) Species as Intermediates

Chemistry – A European Journal, EarlyView.
This work demonstrates the synthesis of cationic Pt(II) η3‐cycloallyl complexes, and experimental and computational studies show a ligand bite‐angle dependence of their formation rates. The reactivity of these complexes with Brønsted acids was investigated, leading to the formation of cationic and dicationic Pt(II) η4‐cyclobutadiene complexes ...
Ouchan He, Froze Jameel, Y. Einar H. Stampehl, Liza M. Richter, Matteo Tosi, Martin Kaupp, Thomas Braun   +6 more
wiley   +1 more source