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Pten regulates zebrafish hematopoiesis
Blood, 2014In this issue of Blood, Choorapoikayil et al have used phosphatase and tensin homolog (Pten)–deficient zebrafish to uncover prominent roles for Pten loss in enhancing proliferation of hematopoietic stem cells (HSCs) and eliciting differentiation arrest within lineage-committed blood progenitor cells.
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2019
PTEN ??? ?????????????????? ?? ?????????????????????????????????? ??????????????????????, ???????????????????????? ?????????????? ???????????????? ?????????????????????? ?? ?????????????????????????????????? ??????????. ???????? ?????????? ?????????? ?????????????????? ?????? ?????????????????????? ???? ???????????? ?????????? ????????????????. ???? ???
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PTEN ??? ?????????????????? ?? ?????????????????????????????????? ??????????????????????, ???????????????????????? ?????????????? ???????????????? ?????????????????????? ?? ?????????????????????????????????? ??????????. ???????? ?????????? ?????????? ?????????????????? ?????? ?????????????????????? ???? ???????????? ?????????? ????????????????. ???? ???
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The functions and regulation of the PTEN tumour suppressor
Nature Reviews Molecular Cell Biology, 2012Leonardo Salmena, Pier Paolo Pandolfi
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The functions and regulation of the PTEN tumour suppressor: new modes and prospects
Nature Reviews Molecular Cell Biology, 2018Yu-Ru Lee +2 more
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Beyond PTEN mutations: the PI3K pathway as an integrator of multiple inputs during tumorigenesis
Nature Reviews Cancer, 2006Megan Cully
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