Results 21 to 30 of about 5,717 (90)

The Malignant Transformation of Viral Hepatitis to Hepatocellular Carcinoma: Mechanisms and Interventions

MedComm, Volume 6, Issue 3, March 2025.
The malignant transformation from chronic viral hepatitis to hepatocellular carcinoma (HCC) involves intricate interactions among viral, host, and environmental factors. Key drivers of this transformation include viral integration, genomic instability, epigenetic modifications, oxidative stress, gut microbiota dysbiosis, chronic inflammation, immune ...
Huimin Yuan, Ruochen Xu, Senlin Li, Mengzhu Zheng, Qingyi Tong, Ming Xiang, Yonghui Zhang   +6 more
wiley   +1 more source

Rôle de la sphingosine 1-phosphate dans les interactions mélanome-stroma

, 2012
Le mélanome métastatique demeure un cancer au sombre pronostic, et aucune des thérapies conventionnelles n'a pu apporter de bénéfice sur la survie globale.
Albinet, Virginie
core  

Need for multi-scale systems to identify spindle orientation regulators relevant to tissue disorganisation in solid cancers

Frontiers in Physiology, 2014
Selina eChin Hui Men, Karandeep eNandra, Joanna eClark, Viji M Draviam   +3 more
doaj   +1 more source

ERα Agonist Protects Aged Female Mice From Sevoflurane Neurotoxicity via PTEN Nuclear Translocation. [PDF]

CNS Neurosci Ther
Zhang X, Lei Y, Gong B, Xu Y, Li D, Yu Y, Li F, Luo J.   +7 more
europepmc   +1 more source

Type and Size of Fluorescent Proteins Modulate the Localization of PTEN and Its Fragments, but Have Little or No Effect on Mutant PTEN or Stressed Cells. [PDF]

J Histochem Cytochem
Kato T, Kawakami Y.
europepmc   +1 more source

The RhoG-Binding Domain of ELMO1 Rescues the PTENopathy-like Phenotype in Oligodendroglial FBD-102b Cells. [PDF]

Int J Mol Sci
Takahashi M, Tanaka M, Yako H, Miyamoto Y, Yamauchi J.   +4 more
europepmc   +1 more source

Betulinic acid is associated with miR-21 modulation, apoptosis and redox changes in breast cancer cells: an in vitro and in silico study. [PDF]

Sci Rep
Mahmoud MA, Abdo H, Mekky M, Salem T, Mabrouk S, Khaled B.   +5 more
europepmc   +1 more source

Serum levels of PTEN and progranulin as potential diagnostic and prognostic biomarkers for severe pneumonia in the elderly. [PDF]

PeerJ
Ge Y, Lu W, Liu J, Liang H, Xu L.
europepmc   +1 more source

Clinicogenomic Landscape and Function of <i>PIK3CA</i>, <i>AKT1</i>, and <i>PTEN</i> Mutations in Breast Cancer. [PDF]

JCO Precis Oncol
Tao JJ, Sisoudiya SD, Tukachinsky H, Schrock AB, Ebot EM, Sivakumar S, Sokol ES, Vasan N.   +7 more
europepmc   +1 more source

Loss of PTEN as an Independent Poor Prognosis Indicator in Lung Adenocarcinoma, but Not in Squamous Cell Carcinoma, Is Associated with an Immunosuppressive Tumor Microenvironment and Distinct Co-Mutational Profiles. [PDF]

Med Sci (Basel)
Houry M, Silva SJ, Artola M, Behrens C, Politi K, Wistuba I, Montuenga L, Exposito F, Calvo A.   +8 more
europepmc   +1 more source