Results 211 to 220 of about 8,395 (249)
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Pteridines and affective disorders
Acta Neuropsychiatrica, 2002The pteridine tetrahydrobiopterin (BH4) is an essential cofactor in the biosynthesis of dopamine, (nor)epinephrine, serotonin and nitric oxide (NO). Furthermore, BH4 has a direct influence on release mechanisms of these neurotransmitters and on serotonin receptor binding activityimmunology.
Hoekstra, R (Rosa), Fekkes, Durk
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Biochemistry of the Pteridines
Angewandte Chemie International Edition in English, 1972AbstractBiochemical information about the ubiquitous pteridines has become generally available only within the last fifteen years. This delay can be traced to the chemical lability of these compounds and their small concentrations in organisms. New methods of isolation and isotopic techniques have provided data on the biosynthesis, anabolism, and ...
H, Rembold, W L, Gyure
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Pteridine, XLI. Zur Synthese von Pteridin‐N‐8‐ribosiden
Chemische Berichte, 1971AbstractZur Synthese der ersten Pteridin‐N‐8‐riboside (912) werden 5‐Nitro‐4‐ribofuranosylamino‐pyrimidine (14) zunächst zu den 5‐Aminoderivaten (5, 6) reduziert, diese dann mit Glyoxyl‐säureester kondensiert (7, 8) und 7, 8 anschließend cyclisiert. Zur Charakterisierung der Produkte dienen UV‐ und NMR‐Spektren.
Hartmut Rokos, Wolfgang Pfleiderer
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Journal of the Chemical Society C: Organic, 1968
Pteridine-2-thiol was reduced by sodium borohydride to the 3,4-dihydro-derivative. Pteridine-2-thiol also reacted readily with sodium hydrogen sulphite and the following potentially carbanionic (‘Michael’) reagents; acetylacetone, ethyl acetoacetate, dimedone, and phloroglucinol.
Adrien Albert, John J. McCormack
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Pteridine-2-thiol was reduced by sodium borohydride to the 3,4-dihydro-derivative. Pteridine-2-thiol also reacted readily with sodium hydrogen sulphite and the following potentially carbanionic (‘Michael’) reagents; acetylacetone, ethyl acetoacetate, dimedone, and phloroglucinol.
Adrien Albert, John J. McCormack
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Pteridine, XVI. Zur Synthese und Struktur von Pteridin‐glykosiden
Chemische Berichte, 1962AbstractAusgehend von 2‐Amino‐4‐alkoxy‐7‐oxo‐dihydropteridinen wurden mit Halogenzuckern in siedendem Xylol und bei Gegenwart von Silbercarbonat Pteridin‐glykoside erhalten. Diese Produkte zeigen neben der erwarteten Säurelabilität der Glykosidbindung auch eine große Hydrolysenempfindlichkeit gegenüber Alkalien, was ebenso wie die UV ...
Wolfgang Pfleiderer, Rolf Lohrmann
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Nature, 1948
ALTHOUGH many derivatives of pteridine, both natural and synthetic, are known, the parent substance pteridine (I) does not appear to have been described. This substance has now been prepared by the condensation of 4 : 5-diaminopyrimidine with glyoxal bisulphite.
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ALTHOUGH many derivatives of pteridine, both natural and synthetic, are known, the parent substance pteridine (I) does not appear to have been described. This substance has now been prepared by the condensation of 4 : 5-diaminopyrimidine with glyoxal bisulphite.
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Pteridines. IX. Some pteridine isomers of triamterene
Journal of Medicinal Chemistry, 1968J, Weinstock, R Y, Dunoff
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Pteridine, VIII. Über 4.6‐ und 4.7‐Dihydroxy‐pteridine
Chemische Berichte, 1959AbstractEine vereinfachte Darstellungsmethode des 4.7‐Dihydroxy‐pteridins wird beschrieben. Das 4.5‐Diamino‐6‐oxo‐dihydropyrimidin und sein 1‐Methylderivat zeigen bei Pteridinsynthesen mit Glyoxylsäureäthylester‐halbacetal und Mesoxalsäure ein den allgemein gültigen Orientierungsregeln entgegengesetztes Verhalten.
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Pteridines. XII. Structure-activity relation of some pteridine diuretics
Journal of Medicinal Chemistry, 1968J, Weinstock +5 more
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