Results 91 to 100 of about 9,547 (224)

QT-AIM analysis of neutral pterin and its anionic and cationic forms

Pteridines, 2014
Quantum theory of atoms in molecules (QT-AIM) allows detailed insight into the electronic structure of molecules by analysis of the gradient vector field of the electronic density distribution function.
Reibnegger Gilbert
doaj   +1 more source

Crystal structure of (2-amino-7-methyl-4-oxidopteridine-6-carboxylato-κ3O4,N5,O6)aqua(1,10-phenanthroline-κ2N,N′)zinc trihydrate

Acta Crystallographica Section E: Crystallographic Communications, 2015
In the title compound, [Zn(C8H5N5O3)(C12H8N2)(H2O)]·3H2O, a tridentate 2-amino-7-methyl-4-oxidopteridine-6-carboxylate ligand, a bidentate ancillary 1,10-phenanthroline (phen) ligand and a water molecule complete a distorted octahedral coordination ...
Siddhartha S. Baisya, Baidyanath Ghosh, Parag S. Roy   +2 more
doaj   +1 more source

Nanosecond photoreduction of inducible nitric oxide synthase by a Ru-diimine electron tunneling wire bound distant from the active site [PDF]

, 2009
A Ru-diimine wire, [(4,4′,5,5′-tetramethylbipyridine)_2Ru(F_9bp)]^(2+) (tmRu-F_9bp, where F_9bp is 4-methyl-4′-methylperfluorobiphenylbipyridine), binds tightly to the oxidase domain of inducible nitric oxide synthase (iNOSoxy). The binding of tmRu-F_9bp
Belliston-Bittner, Wendy, Dunn, Alexander R., Gray, Harry B., Whited, Charlotte A., Winkler, Jay R.   +4 more
core   +1 more source

Accessing Bisphosphine Copper(I) Complexes with Recalcitrant Pterin–Phenanthroline Ligands Through Mechanochemistry

Inorganics
The synthesis of [Cu(PteN˄N)(P˄P)][BF4] complexes with pterin-fused phenanthroline (PteN˄N) derivatives and bisphosphine (P˄P) co-ligands was achieved through a mechanochemical approach. Due to the extremely poor solubility of PteN˄N ligands, traditional
Siva S. M. Bandaru, Christian Fischer, Jevy V. Correia, Anna-Lena Land, Carola Schulzke   +4 more
doaj   +1 more source

Pterin Metabolism In Haemodialysis Patients

Pteridines, 1989
Patients undertaking maintenance haemodialysis may develop a variety of neurological disorders, the most serious of which is aluminium induced encephalopathy.
Altmann Paul, Sawyer Nick, Cunningham John, Marsh Frank, Hamon Chris, Blair John A.   +5 more
doaj   +1 more source

Promiscuous and Adaptable Enzymes Fill “Holes” in the Tetrahydrofolate Pathway in Chlamydia Species

mBio, 2014
Folates are tripartite molecules comprising pterin, para-aminobenzoate (PABA), and glutamate moieties, which are essential cofactors involved in DNA and amino acid synthesis.
Nancy E. Adams, Jennifer J. Thiaville, James Proestos, Ana L. Juárez-Vázquez, Andrea J. McCoy, Francisco Barona-Gómez, Dirk Iwata-Reuyl, Valérie de Crécy-Lagard, Anthony T. Maurelli   +8 more
doaj   +1 more source

Increasing Tetrahydrobiopterin in Cardiomyocytes Adversely Affects Cardiac Redox State and Mitochondrial Function Independently of Changes in NO Production [PDF]

, 2016
Tetrahydrobiopterin (BH4) represents a potential strategy for the treatment of cardiac remodeling, fibrosis and/or diastolic dysfunction. The effects of oral treatment with BH4 (Sapropterin™ or Kuvan™) are however dose-limiting with high dose negating ...
Bennett, Brian, Ionova, Irina A., Pieper, Galen M., Sethumadhavan, Savitha, Vasquez-Vivar, Jeannette, Whitsett, Jennifer   +5 more
core   +1 more source

An in vitro System for Studying Pteridine Biosynthesis In Drosophila melanogaster

Pteridines, 1991
In vitro organ culture is a system especially useful for the study of metabolic pathways and their regulation. This report applies such a system to the study of the biosynthesis of pteridines in Drosophila melanogaster, determining in vitro optimal ...
Escriche B., Silva F. J.
doaj   +1 more source

Xanthine oxidoreductase regulates macrophage IL1β secretion upon NLRP3 inflammasome activation. [PDF]

, 2015
Activation of the NLRP3 inflammasome by microbial ligands or tissue damage requires intracellular generation of reactive oxygen species (ROS). We present evidence that macrophage secretion of IL1β upon stimulation with ATP, crystals or LPS is mediated by
Busso, N., Ives, A., LeRoy, D., Martinon, F., Miner, J.N., Nomura, J., Roger, T., Simon, G., So, A.   +8 more
core   +1 more source

(2-Amino-7-methyl-4-oxidopteridine-6-carboxylato-κ3O4,N5,O6)aqua(1,10-phenanthroline-κ2N,N′)cobalt(II) trihydrate

Acta Crystallographica Section E, 2013
In the title compound, [Co(C8H5N5O3)(C12H8N2)(H2O)]·3H2O, a tridentate 2-amino-7-methyl-4-oxidopteridine-6-carboxylate ligand, a bidentate ancillary 1,10-phenanthroline (phen) ligand and a water molecule complete a distorted octahedral geometry ...
Siddhartha S. Baisya, Samir Sen, Parag S. Roy   +2 more
doaj   +1 more source