Results 101 to 110 of about 5,912 (161)

Pterin-Centered Radical as a Mechanistic Probe of the Second Step of Nitric Oxide Synthase

, 2016
The enzyme nitric oxide synthase is both medically relevant and of particular interest from a basic sciences perspective due to the complex nature of the chemical mechanism used to generate NO.
Joshua J. Woodward (2273068), Michael A. Marletta (1858000), Yaser NejatyJahromy (2273071), R. David Britt (305724)   +3 more
core   +1 more source

Triphenyltin induced darker body coloration by disrupting melanocortin system and pteridine metabolic pathway in a reef fish, Amphiprion ocellaris

Ecotoxicology and Environmental Safety
Triphenyltin (TPT) is a typical persistent organic pollutant whose occurrence in coral reef ecosystems may threaten the survival of reef fishes. In this study, a brightly colored representative reef fish, Amphiprion ocellaris was used to explore the ...
Song Liu, Yu Hou, Ya-jun Shi, Nan Zhang, Yi-guang Hu, Wen-ming Chen, Ji-liang Zhang   +6 more
doaj   +1 more source

Structural Studies of Pterin-Based Inhibitors of Dihydropteroate Synthase

, 2016
Dihydropteroate synthase (DHPS) is a key enzyme in bacterial folate synthesis and the target of the sulfonamide class of antibacterials. Resistance and toxicities associated with sulfonamides have led to a decrease in their clinical use.
Kerim Babaoglu (1648204), Julian G. Hurdle (520207), Kirk E. Hevener (468717), Stephen W. White (145860), Richard E. Lee (284694), Iain D. Kerr (247678), Jianjun Qi (705707), Kanya Balakrishna (2325697), Mi-Kyung Yun (145841)   +8 more
core   +1 more source

Influence of pteridines and statins on cancer: A therapeutic strategy targeting nitric oxide synthase (NOS) pathway

Advances in Redox Research
A family of enzymes known as nitric oxide synthases (NOS) produces nitric oxide (NO), a tiny, unstable, and potentially hazardous gas that is highly diffusible across cell membranes.
Jerimon Johnson, Monisha Krishnan, Sasireka Manikandan, Nivetha Shanmuganathan, Martinahingis Kennedy, Kris Santhiya Yeasuraj, Sridhar Muthusami, Angayarkanni Jayaraman   +7 more
doaj   +1 more source

An Overview of Pterin Analysis in Biological Samples: From Occurrence and Properties to Sample Pretreatment Combined With Hyphenated Separation Techniques. [PDF]

J Sep Sci
Brejcha J, Bosakova Z.
europepmc   +1 more source

Emerging roles of pterins as signaling molecules in bacteria. [PDF]

Biochem Soc Trans
Rucker P, Augusta L, Fuqua C, Allen KD.
europepmc   +1 more source

Structure and function of periplasmic nitrate reductase. [PDF]

Biochem Soc Trans
Mongkonpruthangkoon C, Giri NC, Basu P.
europepmc   +1 more source

Guiding covalent catalysis enables a carbon-inserting rearrangement in molybdenum cofactor biosynthesis. [PDF]

Proc Natl Acad Sci U S A
Li D, Schumacher MA, Yokoyama K.
europepmc   +1 more source

Isolation of folate-producing probiotic candidates and their effects on homocysteine metabolism and gut microbiota composition. [PDF]

Front Nutr
Pan M, Ye C, Song Y, Tian M, Wang R, Chen P.   +5 more
europepmc   +1 more source

Tetrahydromethanopterin as a Two-Carbon Carrier: Formation of <i>N</i>⁵-Ethyl- and <i>N</i>⁵,<i>N</i>¹⁰-Ethylene-Tetrahydromethanopterin in <i>Methanothermobacter marburgensis</i>. [PDF]

Biochemistry
Laird MG, Telimaa H, Koivisto J, Scheller S.   +3 more
europepmc   +1 more source