Electrochemical evidence that pyranopterin redox chemistry controls the catalysis of YedY, a mononuclear Mo enzyme [PDF]
, 2015 A long-standing contradiction in the field of mononuclear Mo enzyme research is that small-molecule chemistry on active-site mimic compounds predicts ligand participation in the electron transfer reactions, but biochemical measurements only suggest metal-
Alan M. Bond +9 more
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Novel Synthesis of 8-Deaza-5,6,7,8-tetrahydroaminopterin Analogues via an Aziridine Intermediate
Molecules, 2012 An efficient method for the construction of the tetrahydrofolate skeleton is described. Starting from pterin analogues and aromatic amines, 8-deaza-5,6,7,8-tetrahydroaminopterin derivatives and the heterocyclic benzoyl isosteres were synthesized via a ...
Zhili Zhang +6 more
doaj +1 more source
UVA photoactivation of harmol enhances its antifungal activity against the phytopathogens Penicillium digitatum and Botrytis cinerea [PDF]
, 2017 Phytopathogenic fungi responsible for post-harvest diseases on fruit and vegetables cause important economic losses. We have previously reported that harmol (1-methyl-9H-pyrido[3,4-b]indol-7-ol) is active against the causal agents of green and gray molds
Cabrerizo, Franco Martín +5 more
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Photosensitization of peptides and proteins by pterin derivatives
Pteridines, 2017 Proteins are one of the preferential targets of the photosensitized damaging effects of ultraviolet (UV) radiation on biological system. Pterins belong to a family of heterocyclic compounds, which are widespread in living systems and participate in ...
Dantola Maria Laura +5 more
doaj +1 more source
Folic Acid With Fluorene: A Complexation Study by UV and FTIR Spectroscopies
Ibn Al-Haitham Journal for Pure and Applied Sciences, 2017 The complexation between folic acid and a typical polyaromatic hydrocarbon, fluorene, was investigated using FTIR and UV spectra. Appearance of a new IR band at 2401cm−1 demonstrates that NH2–C=N moiety on pterin ring in folic acid is protonated ...
K. K. Hammud +4 more
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Theoretical Stereostructure of the Neutral Form of Natural Tetrahydrobiopterin
Pteridines, 1993 The absolute conformation and the reactivity of atoms of the neutral form of natural tetrahydrobiopterin [(6R)-6-(L-erythro-1 ′,2′ -dihydroxypropyl)-5.6.7.8-tetrahydropterin] was determined by the Molecular-Orbital method within the MINDO/3 framework ...
Katoh Setsuko +2 more
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Journal of Biological Chemistry, 1949 O H, LOWRY, O A, BESSEY, E J, CRAWFORD
openaire +2 more sources
Tetrahydrobiopterin and inherited hyperphenylalaninemias
The Turkish Journal of Pediatrics, 1996 Tetrahydrobiopterin deficiency, a variant of hyperphenylalaninemia, may be caused by deficiency of one of the following enzymes: guanosine triphosphate cyclohydrolase 1,6-pyruvoyltetrahydropterin synthase, dihydropteridin reductase and pterin-4a ...
N Blau, B Thony, M Spada, A Ponzone
doaj
The folic acid antagonists and their use is the treatment of acute leukemia [PDF]
, 1954 Thesis (M.D.)--Boston ...
Boyd, George K.
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Dihydrofolate reductase of Streptococcus faecium II. Purification and some properties of two dihydrofolate reductases from the Amethopterin-resistant mutant, Streptococcus Faecium Var. Durans Strain A [PDF]
, 1968 From a single amethopterin-resistant organism, Streptococcus faecium var. durans strain A, two different dihydrofolate reductases have been obtained as essentially homogeneous proteins in good yield.
Blakley, R. L., Nixon, P. F.
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