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All-in-One CO<sub>2</sub> Capture and Transformation: Lessons from Formylmethanofuran Dehydrogenases. [PDF]
Acc Chem ResLemaire ON, Wagner T.
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A Prebiotic Synthesis of Pterins
Chemistry – A European Journal, 2015AbstractThe genesis of life on Earth is a hypothesis of evolutionary science that can be, at least partially, tested experimentally. The prebiotic synthesis of cofactors or coenzymes is a poorly explored issue, likely because their formation under plausible prebiotic conditions is not clear.
Margarita R, Marín-Yaseli +2 more
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Paper Chromatography of Pterins
Nature, 1949THE detection and identification of pterins in small quantities was carried out by Schopf and Becker1 in the course of their classical work on this class of pigments. They employed a chromatographic technique using 0·004 N aqueous hydrochloric acid or 0·01 N methyl alcoholic hydrochloric acid solutions on micro-absorption columns of alumina or ...
P M, GOOD, A W, JOHNSON
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2008
Tetrahydrobiopterin(BH4)cofactor is essential for various enzyme activities, including phenylalanine-4-hydroxylase(PAH), tyrosine-3-hydroxylase(TH), tryptophan-5-hydroxylase(TPH), nitric oxide synthase(NOS), and glyceryl-ether monooxygen-ase(GEMO).The de novo biosynthesis pathway of BH4 from guanosine triphosphate (GTP) involves GTP cyclohydrolase I ...
Blau, N, Thöny, B
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Tetrahydrobiopterin(BH4)cofactor is essential for various enzyme activities, including phenylalanine-4-hydroxylase(PAH), tyrosine-3-hydroxylase(TH), tryptophan-5-hydroxylase(TPH), nitric oxide synthase(NOS), and glyceryl-ether monooxygen-ase(GEMO).The de novo biosynthesis pathway of BH4 from guanosine triphosphate (GTP) involves GTP cyclohydrolase I ...
Blau, N, Thöny, B
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In situ detection of pterins by SERS
The Analyst, 2009Surface enhanced Raman scattering (SERS) has been used to detect specific pterin molecules at sub-nanomolar concentrations. SERS is fast becoming a widely used technique for the sensitive and specific detection of multiple analytes. The information-rich and concentration-dependent spectra obtained from SERS make the technique ideally placed for high ...
Stevenson, Ross +8 more
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Inborn Errors of Pterin Metabolism
Annual Review of Nutrition, 1988HY PERPHENY LALANINEMIA DUE TO TETRAHYDROBIOPTERIN DEFICIENCy 188 GTP Cyclohydrolase I Deficiency 188 6-Pyruvoyl Tetrahydropterin Synthase Deficiency 189 Dihydropteridine Reductase Deficiency 191 Other Forms ...
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Pterins in patients with rett syndrome
American Journal of Medical Genetics, 1986We have found normal concentrations of neopterin, monapterin, isoxanthopterin, biopterin and pterin in the urine of 10 patients with Rett syndrome, and normal values for total biopterin and neopterin in the blood of 4 subjects. Thus, there is no biochemical evidence of a generalized tetrahydrobiopterin deficiency in this syndrome.
E. Boltshauser +5 more
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The Synthesis of Fluorine-Containing Pterins
1993The introduction of fluorine into molecules has been well demonstrated to modify the biological properties significantly1. In heterocyclic compounds this effect is clearly demonstrated through the action of 5-fluorouracil and its nucleosides as inhibitors of thymidylate synthetase.
C, Dunn +3 more
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Inhibition of xanthine oxidase by pterins
Free Radical Research, 1998The effect of a panel of pterins on xanthine oxidase was investigated by measuring formation of urate from xanthine as well as formazan production from nitroblue tetrazolium. The pterin derivatives, depending on their chemical structure, decreased urate as well as formazan generation: 200 microM neopterin and biopterin suppressed urate formation (90 ...
I, Wede +4 more
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