Results 101 to 110 of about 9,548 (210)

A single transgene locus triggers both transcriptional and post-transcriptional silencing through double-stranded RNA production [PDF]

, 2006
Silencing of a target locus by an unlinked silencing locus can result from transcription inhibition (transcriptional gene silencing; TGS) or mRNA degradation (post-transcriptional gene silencing; PTGS), owing to the production of double-stranded RNA (
Blokland, Rik van, Kooter, Jan, Mourrain, Philippe, Vaucheret, Hervé   +3 more
core   +4 more sources

Xanthatin Targets CISD1 to Drive Ferroptosis and Mitophagy as a Dual Anticancer Strategy in Triple‐Negative Breast Cancer

Advanced Science, Volume 13, Issue 21, 13 April 2026.
Triple‐negative breast cancer has a poor prognosis. Xanthatin directly targets and degrades CISD1, triggering ferroptosis through iron dysregulation. The concurrently activated mitophagy synergistically amplifies ferroptotic cell death. Xanthatin also demonstrates potent in vivo anti‐tumor efficacy with minimal toxicity, highlighting its therapeutic ...
Qinwen Liu, Haojie Chen, Xiang Li, Jingxin Liu, Yiwen Li, Zhenyi Shi, Shenshen Guo, Qingfeng Du, Aiping Lu, Daogang Guan   +9 more
wiley   +1 more source

Studies on molecular mechanisms underlying disease resistance of plants : plant-activator-induced resistance against fungal diseases and PTGS-based resistance against viral diseases [PDF]

, 2008
筑波大学University of Tsukuba博士（農学）Doctor of Philosophy in Agricultural Science2007【要旨 ...
76969, Shimono, Masaki, 霜野, 真幸
core  

A perspective: PLA2G4A as drug target for vascular inflammation in Alzheimer's disease

Alzheimer's &Dementia, Volume 22, Issue 4, April 2026.
Abstract Anti‐amyloid therapies for Alzheimer's disease (AD) modestly slow cognitive decline but carry significant risk of amyloid‐related imaging abnormalities (ARIAs), brain swelling, and hemorrhage, particularly in apolipoprotein E ε4 carriers. Cerebral amyloid angiopathy (CAA) and vascular inflammation drive this vulnerability, highlighting the ...
Ambreen Kanwal, Bilal E. Kerman, Shaowei Wang, Kevin Camey, Boyang Li, Lisi Flores‐Aguilar, Nada Ali, Laura Beth McIntire, Chang April Shu, Stan G. Louie, Elizabeth Head, Zoe Arvanitakis, Hussein N. Yassine   +12 more
wiley   +1 more source

Heart Rate Variability as a Biomarker for Posttraumatic Growth: A Comparative Study of Brain Tumor Patients and Caregivers

Cancer Medicine, Volume 15, Issue 4, April 2026.
ABSTRACT Objective To explore the levels and group differences of posttraumatic growth and heart rate variability in a sample of brain tumor patients and their caregivers. Methods Convenience sampling method was adopted, and general information questionnaire, posttraumatic growth scale, and heart rate variability test were applied to survey and test a ...
Tenggang Shen, Ting Shu, Zijun Yuan, Detian Liu, Linxin Xie, Hongzhen Xie   +5 more
wiley   +1 more source

Probabilistic Multi‐Objective Energy Management System Model for an Energy Hub With PtG Technology for Cost Reduction and System Flexibility Improvement

Energy Science &Engineering, Volume 14, Issue 4, Page 1749-1764, April 2026.
Overview of the under‐study hub energy model showing the energy conversion and distribution among integrated sources and loads. ABSTRACT In this paper, a probabilistic bi‐objective energy management system (EMS) model is proposed for an energy hub (EH) equipped with renewable energy sources such as photovoltaic and wind turbine connected to the main ...
Mohammad Khoshabi, Mehrdad Ahmadi Kamarposhti, Mohsen Sedighi, Alireza Ghafouri   +3 more
wiley   +1 more source

Alternative Surgery for Low Grade Thyroid Malignancies

Journal of the Formosan Medical Association, 2009
Traditional surgery for thyroid nodule is usually performed via anatomic localization of the recurrent laryngeal nerve (RLN), inferior thyroid artery and parathyroid glands (PTGs) initially.
Kai-Yuan Hsiao, Jenq-Yuh Ko, Yong-Tsung Hong   +2 more
doaj   +1 more source

Efficient Fully Stretchable Organic Light‐Emitting Diodes

SmartMat, Volume 7, Issue 2, April 2026.
Stretchable OLEDs achieve stable electron injection under mechanical deformation by decoupling electronic function from mechanical compliance via molecular and interfacial design. The combined use of stretchable electron‐transport polymers and liquid‐metal‐modified aluminum cathodes reduces the inherent trade‐off between electrical performance and ...
Lili Sun, Mingjian Ni, Zhiqiang Zhuo, Jinyi Lin, Wei Huang   +4 more
wiley   +1 more source

Biotechnological approaches to determine the impact of viruses in the energy crop plant Jatropha curcas [PDF]

, 2011
Background: Geminiviruses infect a wide range of plant species including Jatropha and cassava both belonging to family Euphorbiaceae. Cassava is traditionally an important food crop in Sub - Saharan countries, while Jatropha is considered as valuable ...
Rose C Ramkat, Alberto Calari, Fatemeh Maghuly, Margit Laimer   +3 more
core   +3 more sources

Upcoming Treatments in Celiac Disease: From Luminal Enzymes to Oral Immune Tolerance

United European Gastroenterology Journal, Volume 14, Issue 3, April 2026.
ABSTRACT Celiac disease (CeD) is a chronic autoimmune enteropathy triggered by dietary gluten in genetically predisposed individuals. Currently, a gluten‐free diet (GFD) is the only available treatment, being effective in improving mucosal health and symptoms. However, a considerable percentage of celiacs continue to exhibit residual mucosal damage and
Juha Taavela, Luca Elli, Gerd Bouma, Jason A. Tye‐Din, Detlef Schuppan, Knut E. A. Lundin, Michael Schumann   +6 more
wiley   +1 more source