Results 241 to 250 of about 190,444 (265)

PTH and stem cells.

Journal of endocrinological investigation, 2012
At least 2 different types of cells, hematopoietic and mesenchymal, are present in the adult bone marrow, in addition to endothelial cells. Hematopoietic and mesenchymal cells are believed to originate from hematopoietic stem cells (HSC) and mesenchymal stem cells (MSC), respectively.
M. Ohishi, E. Schipani
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PTHrP, PTH, and the PTH/PTHrP receptor in endochondral bone development

Birth Defects Research Part C: Embryo Today: Reviews, 2003
AbstractEndochondral bone development is a fascinating story of proliferation, maturation, and death. An understanding of this process at the molecular level is emerging. In particular, significant advances have been made in understanding the role of parathyroid‐hormone‐related peptide (PTHrP), parathyroid hormone (PTH), and the PTH/PTHrP receptor in ...
Ernestina, Schipani, Sylvain, Provot
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PTH spikes during parathyroid exploration—a possible pitfall during PTH monitoring?

Langenbeck's Archives of Surgery, 2006
Parathyroid hormone (PTH) spikes caused by unintentional manipulation of the hypersecreting glands may lead to interpretation problems in intraoperative PTH monitoring. Their frequency and surgical consequences were evaluated.Intraoperative PTH values of 401 patients with primary hyperparathyroidism and single gland disease were analysed. Patients were
Philipp, Riss, Klaus, Kaczirek, Christian, Bieglmayer, Bruno, Niederle   +3 more
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Conformational studies of parathyroid hormone (PTH)/PTH-related protein (PTHrp) chimeric peptides

Biopolymers, 2000
The N-terminal 1-34 segments of both parathyroid hormone (PTH) and parathyroid hormone-related protein (PTHrP) bind and activate the same membrane-embedded G protein-coupled receptor (PTH1 Rc) present on the surface of cells in target tissues such as bone and kidney.
SCHIEVANO, ELISABETTA, MAMMI, STEFANO, L. SILVESTRI, V. BEHAR, M. ROSENBLATT, M. CHOREV, PEGGION, EVARISTO   +6 more
openaire   +2 more sources

PTH-like Peptides.

2004
The present invention relates to peptides that are parathyroid hormone (PTH) analogs, useful for the treatment of hypoparathyroidism and diseases characterized by bone mass reduction, such as osteoporosis, and for stimulating bone repair or favoring the engraftment of a bone implant; to the pharmaceutical compositions comprising these PTH-like peptides
CAPORALE, ANDREA, Fiori, N., SCHIEVANO, ELISABETTA, MAMMI, STEFANO, PEGGION, EVARISTO, Chorev, M., Wittelsberger, A.   +6 more
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Kinetics of PTH Metabolism and PTH Fragments in Chronic Renal Failure

2015
Distribution and metabolic degradation of bPTH was studied in man after infusion of 400 U bPTH and blood sampling up to 2h. Disappearance rates of intact 1-84 bPTH, carboxyl- and amino-regional peptides were calculated for healthy subjects (n = 12); patients suffering from moderate (GFR 15--30 ml/min, n = 4) and advanced (GFR less than or equal to 10 ...
N, Lustenberger, R, Hehrmann, H, Jüppner, G, Delling, R D, Hesch   +4 more
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[PTH assay: whole PTH assay (new IRMA assay)].

Clinical calcium, 2005
The common intact-PTH assay detects not only PTH (1-84) but also PTH (7-84) fragment. Recently, it is reported that PTH (7-84) fragment is the antagonist to PTH (1-84) biological action. Thus, conventional intact-PTH assay might mislead the overestimation of parathyroid function in uremic patients.
Yudo, Tanno, Takashi, Shigematsu
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[PTH preparations].

Nihon rinsho. Japanese journal of clinical medicine, 2016
Parathyroid hormone(PTH) is essential for maintaining serum calcium level. PTH increases serum calcium partly by enhancing bone resorption. Therefore, persistent excessive actions of PTH result in cortical bone loss by increased bone resorption. In contrast, intermittent injections of PTH preparations increase trabecular bone mainly by enhancing bone ...
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PTH Substitution Therapy for Chronic Hypoparathyroidism: PTH 1–84 and Palopegteriparatide

Current Osteoporosis Reports
to describe and compare the efficacy and safety of the main PTH treatments, namely PTH(1-84) and palopegteriparatide, for the management of hypoparathyroidism.neither PTH (1-84) nor PTH(1-34) have been shown a clear and consistent favorable impact on the 24 h urinary calcium excretion normalization, while the positive effect on quality of life is still
Andrea Palermo, Anda Mihaela Naciu, Yu Kwang Tay Donovan, Gaia Tabacco, Guido Zavatta   +4 more
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[Significance of a new PTH assay (the comparison between whole-PTH and intact-PTH assay)].

Clinical calcium, 2005
It has been shown that intact-PTH assay measures not only full-length biologically active PTH with 84 amino acids, but also some PTH fragments such as (7-84) PTH. Whole-PTH assay is a new method believed to react only with (1-84) PTH. Because circulatory concentrations of various fragments of PTH are very high especially in patients with secondary ...
Nobuaki, Ito, Seiji, Fukumoto
openaire   +1 more source