Results 251 to 260 of about 101,059 (295)
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Annales d'Endocrinologie, 2015
Even if the first assay for parathyroid hormone (PTH) was published in the early 1960s, its determination remains a challenge even today. Indeed, in the circulation, PTH is present in its active form (PTH 1-84), but many PTH fragments can also be present.
CAVALIER, Etienne +3 more
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Even if the first assay for parathyroid hormone (PTH) was published in the early 1960s, its determination remains a challenge even today. Indeed, in the circulation, PTH is present in its active form (PTH 1-84), but many PTH fragments can also be present.
CAVALIER, Etienne +3 more
openaire +3 more sources
Endocrinology, 1994
Recent data have shown that PTH down-regulation of its receptor on opossum kidney (OK) cells is not associated with any change in the steady state level of the PTH/PTH-related peptide (PTHrP) receptor messenger RNA. For analysis of down-regulation of the PTH/PTHrP receptor in OK cells, the present work uses a specific receptor anti-serum, SR-2, that is
A B, Abou-Samra +5 more
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Recent data have shown that PTH down-regulation of its receptor on opossum kidney (OK) cells is not associated with any change in the steady state level of the PTH/PTH-related peptide (PTHrP) receptor messenger RNA. For analysis of down-regulation of the PTH/PTHrP receptor in OK cells, the present work uses a specific receptor anti-serum, SR-2, that is
A B, Abou-Samra +5 more
openaire +3 more sources
Comprehensive Physiology, 2016
ABSTRACT PTH and Vitamin D are two major regulators of mineral metabolism. They play critical roles in the maintenance of calcium and phosphate homeostasis as well as the development and maintenance of bone health.
Syed Jalal, Khundmiri +2 more
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ABSTRACT PTH and Vitamin D are two major regulators of mineral metabolism. They play critical roles in the maintenance of calcium and phosphate homeostasis as well as the development and maintenance of bone health.
Syed Jalal, Khundmiri +2 more
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PTH Treatment in Hypoparathyroidism
Current Drug Safety, 2011Hypoparathyroidism (HypoPT) is one of the few major hormone deficiency diseases that are not usually treated with the missing hormone. Bovine parathyroid hormone (PTH) has been purified and used as experimental treatment, as long back as in 1928 by Fuller Albright. Treatment, however, was abolished mainly because of antibody formation and costs.
Sikjaer, Tanja; id_orcid 0000-0002-9074-9570 +2 more
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Journal of endocrinological investigation, 2012
At least 2 different types of cells, hematopoietic and mesenchymal, are present in the adult bone marrow, in addition to endothelial cells. Hematopoietic and mesenchymal cells are believed to originate from hematopoietic stem cells (HSC) and mesenchymal stem cells (MSC), respectively.
M. Ohishi, E. Schipani
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At least 2 different types of cells, hematopoietic and mesenchymal, are present in the adult bone marrow, in addition to endothelial cells. Hematopoietic and mesenchymal cells are believed to originate from hematopoietic stem cells (HSC) and mesenchymal stem cells (MSC), respectively.
M. Ohishi, E. Schipani
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PTH(1–84)/PTH(7–84): a balance of power
American Journal of Physiology-Renal Physiology, 2006This review considers many new basic and clinical aspects of parathyroid hormone (PTH). We focus especially on the identification of PTH fragments and how they may relate to renal failure, diagnosis, and treatment of secondary hyperparathyroidism and renal osteodystrophy.
Peter A, Friedman, William G, Goodman
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PTHrP, PTH, and the PTH/PTHrP receptor in endochondral bone development
Birth Defects Research Part C: Embryo Today: Reviews, 2003AbstractEndochondral bone development is a fascinating story of proliferation, maturation, and death. An understanding of this process at the molecular level is emerging. In particular, significant advances have been made in understanding the role of parathyroid‐hormone‐related peptide (PTHrP), parathyroid hormone (PTH), and the PTH/PTHrP receptor in ...
Ernestina, Schipani, Sylvain, Provot
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Kinetics of PTH Metabolism and PTH Fragments in Chronic Renal Failure
2015Distribution and metabolic degradation of bPTH was studied in man after infusion of 400 U bPTH and blood sampling up to 2h. Disappearance rates of intact 1-84 bPTH, carboxyl- and amino-regional peptides were calculated for healthy subjects (n = 12); patients suffering from moderate (GFR 15--30 ml/min, n = 4) and advanced (GFR less than or equal to 10 ...
N, Lustenberger +4 more
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[Significance of a new PTH assay (the comparison between whole-PTH and intact-PTH assay)].
Clinical calcium, 2005It has been shown that intact-PTH assay measures not only full-length biologically active PTH with 84 amino acids, but also some PTH fragments such as (7-84) PTH. Whole-PTH assay is a new method believed to react only with (1-84) PTH. Because circulatory concentrations of various fragments of PTH are very high especially in patients with secondary ...
Nobuaki, Ito, Seiji, Fukumoto
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Pth 1-84, Pth fragments and bone turnover
American Journal of Kidney Diseases, 2003Hartmut H, Malluche +1 more
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