Results 1 to 10 of about 17,061 (178)
Redox BiologyFibroblast growth factor 23 (FGF23) is a member of endocrine FGF family, along with FGF15/19 and FGF21. Recent reports showed that under pathological conditions, liver produces FGF23, although the role of hepatic FGF23 remains nebulous.
Yoon Seok Jung, Hueng-Sik Choi
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Interactions between FGF23 and vitamin D
Endocrine Connections, 2022 Fibroblast growth factor‐23 (FGF23) controls the homeostasis of both phosphate and vitamin D. Bone-derived FGF23 can suppress the transcription of 1α‐hydroxylase (1α(OH)ase) to reduce renal activation of vitamin D (1,25(OH)2D3).
Mohammed S Razzaque
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Determination of FGF23 Levels for the Diagnosis of FGF23-Mediated Hypophosphatemia
Journal of Bone and Mineral Research, 2022 Fibroblast growth factor‐23 (FGF23) measurement is a critical tool in the evaluation of patients with disordered phosphate homeostasis. Available laboratory reference ranges for blood FGF23 were developed using samples from normophosphatemic individuals.
Iris R Hartley +2 more
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Mouse liver injury induces hepatic macrophage FGF23 production
PLoS ONE, 2022 Fibroblast growth factor 23 (FGF23) is a bone marrow cell produced hormone that functions in the intestine and kidney to regulate phosphate homeostasis.
Pradeep Kumar +5 more
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FGF23 and Phosphate–Cardiovascular Toxins in CKD
Toxins, 2019 Elevated levels of fibroblast growth factor 23 (FGF23) and phosphate are highly associated with increased cardiovascular disease and mortality in patients suffering from chronic kidney disease (CKD).
Isabel Vogt, Maren Leifheit-Nestler
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Orphan nuclear receptor ERR-γ regulates hepatic FGF23 production in acute kidney injury
Proceedings of the National Academy of Sciences of the United States of America, 2021 Significance Bone is the main source of fibroblast growth factor 23 (FGF23), which is important for phosphate and vitamin D homeostasis. In acute kidney injury (AKI), high blood levels of FGF23 are positively correlated with disease progression and ...
Kamalakannan Radhakrishnan +2 more
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Clinical features of Italian adult individuals with X-linked hypophosphatemia: a multicenter retrospective study [PDF]
Endocrine ConnectionsObjective: X-linked hypophosphatemia (XLH) is the most common congenital phosphate disorder affecting individuals throughout the lifespan. We investigated the skeletal burden, the cardiovascular involvement, the diagnostic performance and the therapeutic
Silvia Carrara +31 more
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Cardiovascular DiabetologyBackground Compelling evidence suggests that calcium/phosphorus homeostasis-related parameters may be linked to diabetes mellitus and cardiovascular events.
Jiao Bi +6 more
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Toxins, 2019 Fibroblast growth factor 23 (FGF23) plays a key role in the complex network between the bones and other organs. Initially, it was thought that FGF23 exclusively regulated phosphate and vitamin D metabolism; however, recent research has demonstrated that ...
Cristian Rodelo-Haad +2 more
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Fibroblast Growth Factor 23 as a Prognostic Biomarker in Post‐Myocardial Infarction Outcomes: Influence of Renal Function and Its Modulation by Klotho [PDF]
Journal of the American Heart Association: Cardiovascular and Cerebrovascular DiseaseBackground Elevation of FGF23 (fibroblast growth factor 23) and decreased Klotho levels have been associated with various cardiovascular and renal diseases.
Sara Vázquez‐Sánchez +17 more
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