Results 41 to 50 of about 17,111 (223)
Cell Death and Disease, 2021 The levels of fibroblast growth factor 23 (FGF23) rapidly increases after acute kidney injury (AKI). However, the role of FGF23 in AKI is still unclear.
Huang-Ming Chang +20 more
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International Journal of Nephrology and Renovascular Disease, 2021 Yaser Ammar,1 Amira Mohamed,1 Gihane Khalil,2 Dalia Maharem1 1Internal Medicine Department, Medical Research Institute, Alexandria University, Alexandria, Egypt; 2Chemical Pathology Department, Medical Research Institute, Alexandria University ...
Ammar Y, Mohamed A, Khalil G, Maharem D
doaj
Frontiers in Physiology, 2018 Fibroblast growth factor 23 (FGF23) regulates phosphate homeostasis and vitamin D metabolism. In patients with acute kidney injury (AKI), FGF23 levels rise rapidly after onset of AKI and are associated with AKI progression and increased mortality.
Daniela Egli-Spichtig +2 more
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Glycerol-3-phosphate is a FGF23 regulator derived from the injured kidney.
Journal of Clinical Investigation, 2020 Fibroblast growth factor 23 (FGF23) is a bone-derived hormone that controls blood phosphate levels by increasing renal phosphate excretion and reducing 1,25-dihydroxyvitamin D3 [1,25(OH)2D] production.
P. Simic +24 more
semanticscholar +1 more source
FGF23 and its role in X-linked hypophosphatemia-related morbidity
Orphanet Journal of Rare Diseases, 2019 BackgroundX-linked hypophosphatemia (XLH) is an inherited disease of phosphate metabolism in which inactivating mutations of the Phosphate Regulating Endopeptidase Homolog, X-Linked (PHEX) gene lead to local and systemic effects including impaired growth,
S. Beck-Nielsen +9 more
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Toxins, 2020 Fibroblast Growth Factor 23 (FGF23) and Klotho play an essential role in the regulation of mineral metabolism, and both are altered as a consequence of renal failure.
J. Muñoz-Castañeda +5 more
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Phosphopenic form of osteomalacia in a patient with FGF23 producing tumor
Научно-практическая ревматология, 2022 Oncogenic osteomalacia is an orphan disease caused by the overproduction of fibroblast growth factor 23 (FGF23) in tumors, which leads to impaired bone matrix mineralization. Typical laboratory changes are hypophosphatemia, increased alkaline phosphatase,
A. S. Pushkareva +4 more
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Pleiotropic Actions of FGF23 [PDF]
Toxicologic Pathology, 2017 Fibroblast growth factor-23 (FGF23) is a bone-derived hormone, mainly produced by osteoblasts and osteocytes in response to increased extracellular phosphate and circulating vitamin D hormone. Endocrine FGF23 signaling requires co-expression of the ubiquitously expressed FGF receptor 1 (FGFR1) and the co-receptor α-Klotho (Klotho).
openaire +2 more sources
Renal Failure, 2021 Background Long-term dietary phosphorus excess influences disturbances in mineral metabolism, but it is unclear how rapidly the mineral metabolism responds to short-term dietary change in dialysis populations.
Wan-Chuan Tsai +10 more
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How FGF23 shapes multiple organs in chronic kidney disease
Molecular and Cellular Pediatrics, 2021 Chronic kidney disease (CKD) is associated with distinct alterations in mineral metabolism in children and adults resulting in multiple organ dysfunctions.
M. Leifheit-Nestler, D. Haffner
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