Results 51 to 60 of about 11,489 (185)
International Journal of Nephrology and Renovascular Disease, 2021 Yaser Ammar,1 Amira Mohamed,1 Gihane Khalil,2 Dalia Maharem1 1Internal Medicine Department, Medical Research Institute, Alexandria University, Alexandria, Egypt; 2Chemical Pathology Department, Medical Research Institute, Alexandria University ...
Ammar Y, Mohamed A, Khalil G, Maharem D
doaj
The FGF/FGFR System in the Biology and Therapeutic Landscape of Pediatric CNS Tumors
Medicinal Research Reviews, EarlyView.ABSTRACT Central nervous system (CNS) tumors are the most common solid malignancies in children, comprising a highly heterogeneous group of neoplasms defined by distinct molecular alterations and clinical behaviors. Advances in molecular genetics have underscored the relevance of specific signaling pathways in driving pediatric tumorigenesis, among ...
Serena Filiberti +6 more
wiley +1 more source
Phytotherapy Research, EarlyView.This review summarizes how natural products, mainly including flavonoids, terpenoids, alkaloids, and polyphenols alleviate RA via PI3K/Akt pathway, regulating inflammation, proliferation, apoptosis, angiogenesis, and osteoclast differentiation. The figure was created by Figdraw (https://www.figdraw.com/#/).
Haishuo Ren +10 more
wiley +1 more source
Kidney International Reports, 2017 Fibroblast growth factor 23 (FGF23) could contribute to cardiovascular morbidity in chronic kidney disease. In studies of kidney transplant recipients, a high circulating level of FGF23 has been associated with death and graft loss independently of ...
Frank Bienaimé +8 more
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Renal Failure, 2021 Background Long-term dietary phosphorus excess influences disturbances in mineral metabolism, but it is unclear how rapidly the mineral metabolism responds to short-term dietary change in dialysis populations.
Wan-Chuan Tsai +10 more
doaj +1 more source
Paracrine Effects of FGF23 on the Heart [PDF]
Frontiers in Endocrinology, 2018 Fibroblast growth factor (FGF) 23 is a phosphaturic hormone primarily secreted by osteocytes to maintain phosphate and mineral homeostasis. In patients with and without chronic kidney disease, enhanced circulating FGF23 levels associate with pathologic cardiac remodeling, i.e., left ventricular hypertrophy (LVH) and myocardial fibrosis and increased ...
Maren Leifheit-Nestler, Dieter Haffner
openaire +3 more sources
Fibroblast Growth Factor-23—A Potential Uremic Toxin
Toxins, 2016 Fibroblast growth factor-23 (FGF23) is a circulating member of the FGF family produced mainly by the osteocytes and osteoblasts that can act as a hormone.
Piotr Kuczera +2 more
doaj +1 more source
Cytology‐First Diagnostic Workflow for Melanoma of Unknown Primary With Molecular Profiling
Cytopathology, EarlyView.Cytology‑first diagnostic workflow for melanoma of unknown primary. Fine‑needle aspiration of an enlarged lymph node enables rapid cytologic evaluation and immunocytochemical confirmation of melanocytic lineage (SOX10). This early cytologic diagnosis facilitates timely surgical excision and comprehensive genomic profiling, supporting integrated ...
Hong Yu +3 more
wiley +1 more source
PKC regulates the production of fibroblast growth factor 23 (FGF23).
PLoS ONE, 2019 Serine/threonine protein kinase C (PKC) is activated by diacylglycerol that is released from membrane lipids by phospholipase C in response to activation of G protein-coupled receptors or receptor tyrosine kinases.
Ludmilla Bär +2 more
doaj +1 more source
Hypophosphataemia in adults: approach to diagnosis and management
Internal Medicine Journal, EarlyView.Abstract Hypophosphataemia is a common electrolyte disorder which can have clinically significant consequences for bone, muscle, neurological and haematological function. Its causes range from transient transcellular shifts in hospitalised patients to chronic renal phosphate‐wasting disorders mediated by fibroblast growth factor 23 (FGF23).
Kajanan Parameshwaran +2 more
wiley +1 more source