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Parathyroid hormone (PTH), PTH-derived peptides, and new PTH assays in renal osteodystrophy [PDF]
Kidney International, 2003 Parathyroid hormone (PTH), PTH-derived peptides, and new PTH assays in renal osteodystrophy. Reliable measurements of parathyroid hormone (PTH) concentrations in serum or plasma are critical for the appropriate diagnosis and management of patients with renal osteodystrophy.
Isidro Salusky, William G Goodman
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Molecular and Cellular Endocrinology, 2021
Parathyroid hormone (PTH), which is primarily regulated by extracellular calcium changes, controls calcium and phosphate homeostasis. Different diseases are derived from PTH deficiency (hypoparathyroidism), excess (hyperparathyroidism) and resistance (pseudohypoparathyroidism, PHP).
Giovanna Mantovani, Francesca Marta Elli
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Parathyroid hormone (PTH), which is primarily regulated by extracellular calcium changes, controls calcium and phosphate homeostasis. Different diseases are derived from PTH deficiency (hypoparathyroidism), excess (hyperparathyroidism) and resistance (pseudohypoparathyroidism, PHP).
Giovanna Mantovani, Francesca Marta Elli
openaire +2 more sources
Improved assessment of bone turnover by the PTH-(1-84)/large C-PTH fragments ratio in ESRD patients [PDF]
Kidney International, 2001 Improved assessment of bone turnover by the PTH-(1-84)/large C-PTH fragments ratio in ESRD patients.BackgroundThe “intact” parathyroid hormone (PTH) assay recognizes PTH-(1-84) as well as amino terminally truncated PTH fragments, that is, large ...
Hartmut H Malluche, Zhaopo Geng, Z Geng
exaly +2 more sources
Journal of the American Society of Nephrology, 2022
Full-length parathyroid hormone (PTH 1–84) is crucial for the regulation of calcium and phosphate homeostasis and bone remodeling. PTH 1–84 is metabolized into various PTH fragments, which are measured with varying levels of efficiency by PTH immunoassays.
Candice Z. Ulmer +4 more
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Full-length parathyroid hormone (PTH 1–84) is crucial for the regulation of calcium and phosphate homeostasis and bone remodeling. PTH 1–84 is metabolized into various PTH fragments, which are measured with varying levels of efficiency by PTH immunoassays.
Candice Z. Ulmer +4 more
openaire +2 more sources
Effects of PTH and PTH Hypersecretion on Bone: a Clinical Perspective
Current Osteoporosis Reports, 2020Hyperparathyroidism may be due to an autonomous hypersecretion of parathyroid hormone (PTH) or occurs in response to a number of physiological stimuli. A number of recent findings have provided new insights into the importance of the calcium-parathyroid-vitamin D axis to bone in normal physiology and pathological conditions.PTH is known to affect bone ...
Lars, Rejnmark +1 more
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2015
Parathyroid hormone (PTH) is an 84-amino acid polypeptide endocrine hormone that is produced by the parathyroid glands and secreted into the circulation in response to low calcium levels.
Giancarlo Isaia, Margherita Marchetti
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Parathyroid hormone (PTH) is an 84-amino acid polypeptide endocrine hormone that is produced by the parathyroid glands and secreted into the circulation in response to low calcium levels.
Giancarlo Isaia, Margherita Marchetti
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Clinical calcium, 2005
Injectable forms of parathyroid hormone (PTH) and its N-terminal fragments are bone anabolic agents proven by randomized clinical trials. Alternate delivery forms of parathyroid hormone are under clinical or preclinical studies, including nasal, transdermal, and pulmonary formulations of PTH (1-34).
openaire +3 more sources
Injectable forms of parathyroid hormone (PTH) and its N-terminal fragments are bone anabolic agents proven by randomized clinical trials. Alternate delivery forms of parathyroid hormone are under clinical or preclinical studies, including nasal, transdermal, and pulmonary formulations of PTH (1-34).
openaire +3 more sources
Parathyroid Hormone (PTH) Suppresses Rat PTH/PTH-Related Protein Receptor Gene Promoter
Biochemical and Biophysical Research Communications, 2001Parathyroid hormone (PTH) regulates osteoblasts via a G protein-linked PTH/PTH-related protein (PTHrP) receptor. PTH effects on PTH/PTHrP receptor gene expression were studied in UMR 106 osteoblast-like cells. In heterogeneous nuclear RNA and Northern analysis, PTH suppressed PTH/PTHrP receptor transcription.
T, Kawane +3 more
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PTH Receptors and Skeletal Resistance to PTH Action
2020Secondary hyperparathyroidism (SHPT) is an integral component of chronic kidney disease-mineral and bone disorder (CKD-MBD). Many factors have been associated with its development and progression, but the presence of skeletal or calcemic resistance to the action of PTH in CKD has often gone unnoticed.
Jordi Bover +5 more
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