Results 41 to 50 of about 73,900 (261)

Sinodalidad, liderazgo y mujeres en la Iglesia local

Cuestiones Teológicas
En el marco del actual proceso de sinodalización de la Iglesia Católica, temáticas como el rol de las iglesias locales, una mayor participación de todos los miembros del Pueblo de Dios en instancias y roles de liderazgo y, particularmente, el lugar de ...
Carolina Bacher Martínez, Catalina Cerda-Planas   +1 more
doaj   +1 more source

Electrostatically‐Stabilized PEG‐Free Lipid Nanoparticles for Systemic Nucleic Acid Delivery

Advanced Functional Materials, EarlyView.
This work describes non‐PEGylated layered lipid nanoparticles (nonPEG LLNPs), a gene delivery platform that improves upon standard PEGylated LNPs via electrostatic adsorption of charged polymers. nonPEG LLNPs maintain colloidal stability under biological stresses, enhance circulation time, and mitigate accelerated blood clearance and hepatic ...
Namita Nabar, Deeksha Kumaresh, Eduardo Nombera Bueno, Mae Pryor, Paula T. Hammond   +4 more
wiley   +1 more source

CKD–MBD in chronic hemodialysis patients. Are we compliant with the KDIGO 2017 recommendations?

Batna Journal of Medical Sciences
Introduction: Mineral and bone disorders related to chronic kidney disease (CKD-MBD) are a major complication in patients on chronic hemodialysis. Their clinical consequences and prognostic impact require regular assessment and close monitoring.
Nouara BENKACIMI, Saliha LAHFAYA, Farida AIT MESSAOUD, Fatima TAOURIRI, Sabiha BELHAOUA, Amina MAADADI, Abdelkader HASROUF, Mourad KASTALI   +7 more
doaj   +1 more source

Engineered Microvascular Model of the Blood–Brain–Tumor Barrier Reveals Endothelial Remodeling in Diffuse Midline Glioma

Advanced Healthcare Materials, EarlyView.
We developed a patient‐derived, functional microfluidic model of the diffuse midline glioma (DMG) blood–brain–tumor barrier (BBTB) comprised of endothelial cells, astrocytes, pericytes, and tumor cells. The system forms perfusable microvasculature, reveals the BBTB retains vascular integrity, identifies DMG‐specific transcriptomic changes distinct from
Kimberly R. Bennett, Yann S. Vanrobaeys, Tessy Teboh, Zakiya Smith, Anderson Scott, Cynthia Hajal, Paula T. Hammond, Joelle P. Straehla   +7 more
wiley   +1 more source

Evaluating Osteogenic Differentiation of Osteoblastic Precursors Upon Intermittent Administration of PTH/IGFBP7

Frontiers in Pharmacology, 2022
Parathyroid hormone (PTH) 1–34 is the first anabolic agent approved for the treatment of osteoporosis. Preclinical evidence shows a potential association between PTH and osteosarcoma. The mechanisms mediating the bone- and neoplasm-forming effects of PTH
Han Xia, Yueyang Tian, Yile Lin, Qia Huang, Yuan Xue   +4 more
doaj   +1 more source

Sub‐Nanometer Curvature Unlocks Quantum Orbital Flexoelectricity in Graphene

Advanced Materials, EarlyView.
In self‐assembled, reproducible, large‐area, quasi‐pristine graphene nanowrinkles, extreme curvature forces out‐of‐plane π‐electrons toward hybridization, driving a transition from classical to quantum orbital flexoelectricity. As curvature approaches the fundamental physical limit set by the C─C bond length, the resulting polarization increases by ...
Sathvik Ajay Iyengar, James G. McHugh, Jonathan P. Salvage, Robert Vajtai, Venkataramana Gadhamshetty, Alan B. Dalton, Manoj Tripathi, Pulickel M. Ajayan, Vincent Meunier   +8 more
wiley   +1 more source

Nonwoven‐Based Textile Architectures for Energy Storage Applications: Materials, Preparation, Characterization, and Prospects

Advanced Materials Interfaces, EarlyView.
Nonwoven textile architectures are emerging as versatile platforms for next‐generation energy storage, demonstrating how tailored materials and fabrication strategies enhance ion transport, conductivity, flexibility, and scalability for high‐performance sustainable devices.
Tarikul Islam, Md. Hanif Munshi, Rijon Saha, Shaikh Almoon Hussain, Aqib Adnan Shafin, Shumsul Arefin, Md. Kamruzzaman   +6 more
wiley   +1 more source

Relationship between GFR, intact PTH, oxidized PTH, non‐oxidized PTH as well as FGF23 in patients with CKD [PDF]

The FASEB Journal, 2020
Abstract Fibroblast growth factor 23 (FGF23) and parathyroid hormone (PTH) are regulators of renal phosphate excretion and vitamin D metabolism. In chronic kidney disease (CKD), circulating FGF23 and PTH concentrations progressively increase as renal function declines.
Zeng, Shufei, Querfeld, Uwe, Feger, Martina, Haffner, Dieter, Hasan, Ahmed A. (Dr. rer. nat.), Chu, Chang, Slowinski, Torsten, Bernd Dschietzig, Thomas, Schaefer, Franz, Xiong, Yingquan, Zhang, Bingbing, Rausch, Steffen, Horvathova, Katarina, Lang, Florian, Krämer, Bernhard (Prof. Dr. med.), Föller, Michael, Hocher, Berthold (Prof.)   +16 more
openaire   +3 more sources

DRIVE‐SAFE: Data‐Driven Robustness and Informed Validation for Evolving Specifications via Formal Evaluation

Advanced Robotics Research, EarlyView.
DRIVE‐SAFE evaluates learning‐based, black‐box autonomous driving policies against evolving temporal safety requirements using Signal Temporal Logic robustness metrics. It aggregates distributional robustness measures with domain‐informed weights to guide iterative retraining.
Kristy Sakano, Jianyu An, Dinesh Manocha, Huan Xu   +3 more
wiley   +1 more source

Exogenous PTH 1-34 Attenuates Impaired Fracture Healing in Endogenous PTH Deficiency Mice via Activating Indian Hedgehog Signaling Pathway and Accelerating Endochondral Ossification

Frontiers in Cell and Developmental Biology, 2022
Fracture healing is a complicated, long-term, and multistage repair process. Intermittent administration of parathyroid hormone (PTH) has been proven effective on intramembranous and endochondral bone formation during the fracture healing process ...
Cheng Ma, Huan Liu, Yifan Wei, He Li, Dengshun Miao, Yongxin Ren   +5 more
doaj   +1 more source