Results 181 to 190 of about 112,141 (241)

Structural and biochemical analyses of a novel bacterial dual specificity phosphatase from Candidatus Chlorohelix allophototropha. [PDF]

J Microbiol
Jung S, Park SH, Choi JS, Shin HC, Kim SJ, Ku B.   +5 more
europepmc   +1 more source

The diagnostic performance of the YEARS and Pulmonary Embolism Graduated D-dimer algorithms in patients with prior venous thrombosis suspected of pulmonary embolism. [PDF]

Res Pract Thromb Haemost
Martens ESL, Mai V, Bates V, Delluc A, Girard P, Huisman MV, Kahn SR, Kearon C, Kovacs MJ, Pecarskie A, Righini M, Rodger M, Scarvelis D, Schulman S, Shivakumar S, Tan M, Thiruganasambandamoorthy V, Visser S, Wells PS, Le Gal G, Klok FA.   +20 more
europepmc   +1 more source

Downregulation of Protein Tyrosine Phosphatase PTP-BL Represses Adipogenesis

International Journal of Biochemistry and Cell Biology, 2009
Contains fulltext : 80913.pdf (Publisher’s version ) (Closed access)The insulin/insulin-like growth factor 1 (IGF-1) signaling pathway is a major regulator of adipose tissue growth and differentiation.
Wiljan Hendriks, Lluis Fajas, Gilles Freiss   +2 more
exaly   +2 more sources

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Role of Tyrosine Phosphorylation in PTP–PEST

The Journal of Physical Chemistry B, 2023
We study the influence of tyrosine phosphorylation on PTP-PEST, a cytosolic protein tyrosine phosphatase. Utilizing a combination of experimental data and computational modeling, specific tyrosine sites, notably Y64 and Y88, are identified for potential phosphorylation.
T S Sreevidya, Amrutha Manikandan, N Manoj, Madhulika Dixit, Satyavani Vemparala   +4 more
openaire   +2 more sources

PTP is Meaningless, T‐PTP is Contradictory: A Reply to Trueman

Cladistics, 1998
Abstract — The T‐PTP test for monophyly can attribute significance to entirely unsupported groups and even to both of two contradictory alternatives. The method of evaluating “support” after replacing selected groups of terminals with reconstructed ancestors has similar drawbacks.
James M, Carpenter, Pablo A, Goloboff, James S, Farris   +2 more
openaire   +2 more sources

PTPs: Degrading the Undruggable

Journal of Medicinal Chemistry, 2020
By using a proteolysis-targeting chimera (PROTAC) strategy that couples an allosteric, reversible PTP inhibitor with an E3 ligase targeting ligand through a well-designed linker, the first molecule to successfully inhibit PTP activity through degradation has been developed.
openaire   +2 more sources