Results 71 to 80 of about 92,645 (204)

The magnitude and economic replacement value of wild meat obtained from ‘recreational’ big game hunting in the United States

People and Nature, EarlyView.
Abstract Meat production has notable benefits for food security, nutrition and various production economies, but has elicited substantial negative environmental impacts. Recreational hunting provides an alternative to agricultural meat production for over 24 million hunters worldwide.
Shane P. Mahoney, Richard D. Honor
wiley   +1 more source

The Multifaceted Role of Rad9 in the DNA Damage Response of Saccharomyces cerevisiae

Yeast, EarlyView.
ABSTRACT To maintain the integrity of the genome, cells have evolved a complex signalling system, termed the DNA damage response (DDR), which detects DNA damage and promotes DNA repair. To date, over 600 proteins have been identified that play an integral role in the DDR. RAD9, encoding a DDR mediator protein, was the prototypical DNA damage checkpoint
A. Kiely, F. O'Halloran, P. Young, N. F. Lowndes, M. Grenon, K. Finn   +5 more
wiley   +1 more source

Multiterminal High‐Voltage Direct Current Projects: A Comprehensive Assessment and Future Prospects

High Voltage, EarlyView.
ABSTRACT Multiterminal high‐voltage direct current (MT‐HVDC) systems are an important part of modern power systems, addressing the need for bulk power delivery and efficient renewable energy integration. This paper provides a comprehensive overview of recent advances in MT‐HVDC technology, including launched projects and ongoing initiatives.
Mohammad Hossein Mousavi, Hassan Moradi, Kumars Rouzbehi, Vijay K. Sood   +3 more
wiley   +1 more source

Low‐nitrogen addition amplifies the positive effect of grazing exclusion on plant diversity and community stability

Functional Ecology, EarlyView.
Read the free Plain Language Summary for this article on the Journal blog. Abstract Grazing exclusion is widely used for grassland restoration but often improves productivity slowly, whereas nitrogen (N) addition can rapidly boost productivity yet may erode plant diversity and community stability over the long term.
Chunping Zhang, Kang Yang, Zhifa Zang, Mengmeng Lu, Sihan Chen, Yuansheng Huang, Jiaxin Li   +6 more
wiley   +1 more source

Impact of screening programmes for type 1 diabetes in youth: A systematic review and meta‐analysis

Diabetic Medicine, EarlyView.
Abstract Aim To evaluate the impact of anti‐islet antibody (IAb) screening on the general population and first‐degree relatives (FDRs)/high‐risk individuals and evidence‐based follow‐up modalities. Methods We performed this review through systematic searches of PubMed, EMBASE, Cochrane Library, Web of Science, ClinicalTrials.gov and International ...
Roberto Franceschi, Enza Mozzillo, Marco Marigliano, Giulio Maltoni, Ernesto Maddaloni, Rocco Amendolara, Luca Bernardini, Riccardo Bonfanti, Federica Ciambrelli, Francesca Di Candia, Ludovica Fedi, Alessandro Fierro, Dario Iafusco, Antonio Iannilli, Letizia Leonardi, Claudio Maffeis, Evelina Maines, Riccardo Pertile, Claudia Piona, Ivana Rabbone, Carlo Ripoli, Andrea Scozzarella, Valentina Tiberi, Raffaella Buzzetti, Valentino Cherubini   +24 more
wiley   +1 more source

Applying Progress Testing to Undergraduate Periodontal Courses—A First Evaluation After 2 Years of Use in a German University

European Journal of Dental Education, EarlyView.
ABSTRACT Background The Progress Test in Periodontology (PTP) has been implemented at Kiel University to gain an impression of students' learning process in this specific subdiscipline of periodontology within the dental curriculum. Methods The PTP has been designed following internationally established standards and has been adapted into the context ...
Anna Louisa Kollster, Miriam Cyris, Jonas Conrad, Mohamed Mekhemar, Christof E. Dörfer, Christian Graetz   +5 more
wiley   +1 more source

Targeting LMW‐PTP to sensitize melanoma cancer cells toward chemo‐ and radiotherapy

Cancer Medicine, 2018
Tumor resistance to apoptosis is one the main causes of anticancer treatment failure. Previous studies showed that LMW‐PTP overexpression enhances resistance of cancer cells to traditional anticancer drugs.
Giulia Lori, Paolo Paoli, Anna Caselli, Paolo Cirri, Riccardo Marzocchini, Monica Mangoni, Cinzia Talamonti, Lorenzo Livi, Giovanni Raugei   +8 more
doaj   +1 more source

ER proteostasis meets mitochondrial function: contact sites as hubs of communication and therapeutic targets

The FEBS Journal, EarlyView.
Proteostasis ensures proper protein folding, modification, and degradation, while its impairment triggers ER stress. Chronic ER stress and maladaptive UPR via the CHOP–ERO1 axis remodel ERMCs, altering calcium signaling and mitochondrial metabolism.
Giorgia Maria Renna, Alessandro Cherubini, Ersilia Varone, Serena Germani, Alice Marrazza, Ester Zito   +5 more
wiley   +1 more source

Loss of TC-PTP in keratinocytes leads to increased UVB-induced autophagy

Cell Death Discovery
Ultraviolet B (UVB) radiation can distort cellular homeostasis and predispose the skin to carcinogenesis. Amongst the deteriorating effects of the sun’s UVB radiation on cellular homeostasis is the formation of DNA photoproducts.
Obed Asare, Lindsey Shim, Cheol-Jung Lee, Jose Delgado, Natasha Quailes, Klarissa Zavala, Junsoo Park, Bilal Bin Hafeez, Yong-Yeon Cho, Subhash C. Chauhan, Dae Joon Kim   +10 more
doaj   +1 more source

MODY calculator applied in patients with clinical diagnosis of type 1 diabetes mellitus: Is a higher cutoff needed?

Heliyon
Aim: This study aimed to evaluate the mean post-test probability (PTP) of the Maturity-onset diabetes of the young (MODY) calculator in a multiethnic cohort of patients previously diagnosed with type 1 diabetes (T1DM).
Vinícius Vigliazzi Peghinelli, Maria Teresa De Sibio, Igor de Carvalho Depra, Milena Gurgel Teles Bezerra, Marna Eliana Sakalem, Adriano Francisco De Marchi Júnior, Paula Barreto da Rocha, Helena Paim Tilli, Bianca Mariani Gonçalves, Ester Mariane Vieira, Mariana Menezes Lourenço, Célia Regina Nogueira   +11 more
doaj   +1 more source